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Feasibility of 11C-acetate PET/CT for imaging of fatty acid synthesis in the atherosclerotic vessel wall.

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Feasibility of 11C-acetate PET/CT for imaging of fatty acid synthesis in the atherosclerotic vessel wall. / Derlin, Thorsten; Habermann, Christian; Lengyel, Zsolt; Busch, Jasmin Desiree; Wisotzki, Christian; Mester, Janos; Pávics, László.

In: J NUCL MED, Vol. 52, No. 12, 12, 2011, p. 1848-1854.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Derlin, T, Habermann, C, Lengyel, Z, Busch, JD, Wisotzki, C, Mester, J & Pávics, L 2011, 'Feasibility of 11C-acetate PET/CT for imaging of fatty acid synthesis in the atherosclerotic vessel wall.', J NUCL MED, vol. 52, no. 12, 12, pp. 1848-1854. <http://www.ncbi.nlm.nih.gov/pubmed/22065877?dopt=Citation>

APA

Derlin, T., Habermann, C., Lengyel, Z., Busch, J. D., Wisotzki, C., Mester, J., & Pávics, L. (2011). Feasibility of 11C-acetate PET/CT for imaging of fatty acid synthesis in the atherosclerotic vessel wall. J NUCL MED, 52(12), 1848-1854. [12]. http://www.ncbi.nlm.nih.gov/pubmed/22065877?dopt=Citation

Vancouver

Derlin T, Habermann C, Lengyel Z, Busch JD, Wisotzki C, Mester J et al. Feasibility of 11C-acetate PET/CT for imaging of fatty acid synthesis in the atherosclerotic vessel wall. J NUCL MED. 2011;52(12):1848-1854. 12.

Bibtex

@article{20ee98ba2f57414aaa7516239b60dd11,
title = "Feasibility of 11C-acetate PET/CT for imaging of fatty acid synthesis in the atherosclerotic vessel wall.",
abstract = "Fatty acids are a common constituent of atherosclerotic plaque and may be synthesized in the plaque itself. Fatty acid synthesis requires acetyl-coenzyme-A (CoA) as a main substrate, which is produced from acetate. Currently, (11)C-acetate PET/CT is used for the evaluation of malignancies. There are no data concerning its potential for the characterization of atherosclerotic plaque. Therefore, the purpose of the present study was to examine the prevalence, distribution, and topographic relationship of arterial (11)C-acetate uptake and vascular calcification in major arteries.",
keywords = "Adult, Humans, Male, Aged, Female, Middle Aged, Risk Factors, Cohort Studies, Reproducibility of Results, Feasibility Studies, Biological Transport, Acetates/*diagnostic use/metabolism, Arteries/*metabolism, Atherosclerosis/complications/*metabolism/*radionuclide imaging, Calcinosis/complications/radionuclide imaging, Carbon Radioisotopes/diagnostic use, Fatty Acids/*biosynthesis, Plaque, Atherosclerotic/metabolism/radionuclide imaging, Positron-Emission Tomography and Computed Tomography/*methods, Adult, Humans, Male, Aged, Female, Middle Aged, Risk Factors, Cohort Studies, Reproducibility of Results, Feasibility Studies, Biological Transport, Acetates/*diagnostic use/metabolism, Arteries/*metabolism, Atherosclerosis/complications/*metabolism/*radionuclide imaging, Calcinosis/complications/radionuclide imaging, Carbon Radioisotopes/diagnostic use, Fatty Acids/*biosynthesis, Plaque, Atherosclerotic/metabolism/radionuclide imaging, Positron-Emission Tomography and Computed Tomography/*methods",
author = "Thorsten Derlin and Christian Habermann and Zsolt Lengyel and Busch, {Jasmin Desiree} and Christian Wisotzki and Janos Mester and L{\'a}szl{\'o} P{\'a}vics",
year = "2011",
language = "English",
volume = "52",
pages = "1848--1854",
journal = "J NUCL MED",
issn = "0161-5505",
publisher = "Society of Nuclear Medicine Inc.",
number = "12",

}

RIS

TY - JOUR

T1 - Feasibility of 11C-acetate PET/CT for imaging of fatty acid synthesis in the atherosclerotic vessel wall.

AU - Derlin, Thorsten

AU - Habermann, Christian

AU - Lengyel, Zsolt

AU - Busch, Jasmin Desiree

AU - Wisotzki, Christian

AU - Mester, Janos

AU - Pávics, László

PY - 2011

Y1 - 2011

N2 - Fatty acids are a common constituent of atherosclerotic plaque and may be synthesized in the plaque itself. Fatty acid synthesis requires acetyl-coenzyme-A (CoA) as a main substrate, which is produced from acetate. Currently, (11)C-acetate PET/CT is used for the evaluation of malignancies. There are no data concerning its potential for the characterization of atherosclerotic plaque. Therefore, the purpose of the present study was to examine the prevalence, distribution, and topographic relationship of arterial (11)C-acetate uptake and vascular calcification in major arteries.

AB - Fatty acids are a common constituent of atherosclerotic plaque and may be synthesized in the plaque itself. Fatty acid synthesis requires acetyl-coenzyme-A (CoA) as a main substrate, which is produced from acetate. Currently, (11)C-acetate PET/CT is used for the evaluation of malignancies. There are no data concerning its potential for the characterization of atherosclerotic plaque. Therefore, the purpose of the present study was to examine the prevalence, distribution, and topographic relationship of arterial (11)C-acetate uptake and vascular calcification in major arteries.

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Risk Factors

KW - Cohort Studies

KW - Reproducibility of Results

KW - Feasibility Studies

KW - Biological Transport

KW - Acetates/diagnostic use/metabolism

KW - Arteries/metabolism

KW - Atherosclerosis/complications/metabolism/radionuclide imaging

KW - Calcinosis/complications/radionuclide imaging

KW - Carbon Radioisotopes/diagnostic use

KW - Fatty Acids/biosynthesis

KW - Plaque, Atherosclerotic/metabolism/radionuclide imaging

KW - Positron-Emission Tomography and Computed Tomography/methods

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Risk Factors

KW - Cohort Studies

KW - Reproducibility of Results

KW - Feasibility Studies

KW - Biological Transport

KW - Acetates/diagnostic use/metabolism

KW - Arteries/metabolism

KW - Atherosclerosis/complications/metabolism/radionuclide imaging

KW - Calcinosis/complications/radionuclide imaging

KW - Carbon Radioisotopes/diagnostic use

KW - Fatty Acids/biosynthesis

KW - Plaque, Atherosclerotic/metabolism/radionuclide imaging

KW - Positron-Emission Tomography and Computed Tomography/methods

M3 - SCORING: Journal article

VL - 52

SP - 1848

EP - 1854

JO - J NUCL MED

JF - J NUCL MED

SN - 0161-5505

IS - 12

M1 - 12

ER -