Expression of keratins in cutaneous epithelial tumors and related disorders--distribution and clinical significance.

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Expression of keratins in cutaneous epithelial tumors and related disorders--distribution and clinical significance. / Kurokawa, Ichiro; Takahashi, Kenzo; Moll, Ingrid; Moll, Roland.

In: EXP DERMATOL, Vol. 20, No. 3, 3, 2011, p. 217-228.

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@article{b5789eb3bbb94fd89664dd1527f7faeb,
title = "Expression of keratins in cutaneous epithelial tumors and related disorders--distribution and clinical significance.",
abstract = "Keratins are a highly diverse family of cytoskeletal proteins and important markers of epithelial cell differentiation. In this review, applying the new keratin nomenclature recently introduced, we summarize and discuss the distribution and significance of keratin patterns in cutaneous epithelial tumors in relation to the epithelial structures of normal human skin. The available literature data show that the analysis of keratin profiles broadens our understanding of the differentiation, nature and histogenetic origin of the various, highly singular epithelial tumors arising in the skin. Moreover, keratins may aid in histological diagnosis and, in certain instances, may be helpful for the recognition of tumor malignancy and aggressiveness. Furthermore, we briefly address the topic of keratin-related skin disorders.",
keywords = "Animals, Humans, Skin/cytology/metabolism, Keratins/classification/genetics/*metabolism, Neoplasms, Glandular and Epithelial/diagnosis/*metabolism, Skin Neoplasms/diagnosis/*metabolism, Animals, Humans, Skin/cytology/metabolism, Keratins/classification/genetics/*metabolism, Neoplasms, Glandular and Epithelial/diagnosis/*metabolism, Skin Neoplasms/diagnosis/*metabolism",
author = "Ichiro Kurokawa and Kenzo Takahashi and Ingrid Moll and Roland Moll",
year = "2011",
language = "English",
volume = "20",
pages = "217--228",
journal = "EXP DERMATOL",
issn = "0906-6705",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - Expression of keratins in cutaneous epithelial tumors and related disorders--distribution and clinical significance.

AU - Kurokawa, Ichiro

AU - Takahashi, Kenzo

AU - Moll, Ingrid

AU - Moll, Roland

PY - 2011

Y1 - 2011

N2 - Keratins are a highly diverse family of cytoskeletal proteins and important markers of epithelial cell differentiation. In this review, applying the new keratin nomenclature recently introduced, we summarize and discuss the distribution and significance of keratin patterns in cutaneous epithelial tumors in relation to the epithelial structures of normal human skin. The available literature data show that the analysis of keratin profiles broadens our understanding of the differentiation, nature and histogenetic origin of the various, highly singular epithelial tumors arising in the skin. Moreover, keratins may aid in histological diagnosis and, in certain instances, may be helpful for the recognition of tumor malignancy and aggressiveness. Furthermore, we briefly address the topic of keratin-related skin disorders.

AB - Keratins are a highly diverse family of cytoskeletal proteins and important markers of epithelial cell differentiation. In this review, applying the new keratin nomenclature recently introduced, we summarize and discuss the distribution and significance of keratin patterns in cutaneous epithelial tumors in relation to the epithelial structures of normal human skin. The available literature data show that the analysis of keratin profiles broadens our understanding of the differentiation, nature and histogenetic origin of the various, highly singular epithelial tumors arising in the skin. Moreover, keratins may aid in histological diagnosis and, in certain instances, may be helpful for the recognition of tumor malignancy and aggressiveness. Furthermore, we briefly address the topic of keratin-related skin disorders.

KW - Animals

KW - Humans

KW - Skin/cytology/metabolism

KW - Keratins/classification/genetics/metabolism

KW - Neoplasms, Glandular and Epithelial/diagnosis/metabolism

KW - Skin Neoplasms/diagnosis/metabolism

KW - Animals

KW - Humans

KW - Skin/cytology/metabolism

KW - Keratins/classification/genetics/metabolism

KW - Neoplasms, Glandular and Epithelial/diagnosis/metabolism

KW - Skin Neoplasms/diagnosis/metabolism

M3 - SCORING: Journal article

VL - 20

SP - 217

EP - 228

JO - EXP DERMATOL

JF - EXP DERMATOL

SN - 0906-6705

IS - 3

M1 - 3

ER -