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Expression of glycogenes in differentiating human NT2N neurons. Downregulation of fucosyltransferase 9 leads to decreased Lewis(x) levels and impaired neurite outgrowth.

Standard

Expression of glycogenes in differentiating human NT2N neurons. Downregulation of fucosyltransferase 9 leads to decreased Lewis(x) levels and impaired neurite outgrowth. / Gouveia, Ricardo; Schaffer, Lana; Papp, Suzanne; Grammel, Nicolas; Kandzia, Sebastian; Head, Steven R; Kleene, Ralf; Schachner, Melitta; Conradt, Harald S; Costa, Júlia.

In: Biochim Biophys Acta, Vol. 1820, No. 12, 12, 2012, p. 2007-2019.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Gouveia, R, Schaffer, L, Papp, S, Grammel, N, Kandzia, S, Head, SR, Kleene, R, Schachner, M, Conradt, HS & Costa, J 2012, 'Expression of glycogenes in differentiating human NT2N neurons. Downregulation of fucosyltransferase 9 leads to decreased Lewis(x) levels and impaired neurite outgrowth.', Biochim Biophys Acta, vol. 1820, no. 12, 12, pp. 2007-2019. <http://www.ncbi.nlm.nih.gov/pubmed/23000574?dopt=Citation>

APA

Gouveia, R., Schaffer, L., Papp, S., Grammel, N., Kandzia, S., Head, S. R., Kleene, R., Schachner, M., Conradt, H. S., & Costa, J. (2012). Expression of glycogenes in differentiating human NT2N neurons. Downregulation of fucosyltransferase 9 leads to decreased Lewis(x) levels and impaired neurite outgrowth. Biochim Biophys Acta, 1820(12), 2007-2019. [12]. http://www.ncbi.nlm.nih.gov/pubmed/23000574?dopt=Citation

Vancouver

Gouveia R, Schaffer L, Papp S, Grammel N, Kandzia S, Head SR et al. Expression of glycogenes in differentiating human NT2N neurons. Downregulation of fucosyltransferase 9 leads to decreased Lewis(x) levels and impaired neurite outgrowth. Biochim Biophys Acta. 2012;1820(12):2007-2019. 12.

Bibtex

@article{d0d1972b9c1f4108b553a8fa69f7aab7,
title = "Expression of glycogenes in differentiating human NT2N neurons. Downregulation of fucosyltransferase 9 leads to decreased Lewis(x) levels and impaired neurite outgrowth.",
abstract = "Several glycan structures are functionally relevant in biological events associated with differentiation and regeneration which occur in the central nervous system. Here we have analysed the glycogene expression and glycosylation patterns during human NT2N neuron differentiation. We have further studied the impact of downregulating fucosyltransferase 9 (FUT9) on neurite outgrowth.",
keywords = "Humans, Cells, Cultured, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Amino Acid Sequence, Molecular Sequence Data, Oligonucleotide Array Sequence Analysis, Blotting, Western, Immunoprecipitation, Down-Regulation, *Cell Differentiation, Glycosylation, Polysaccharides/*metabolism, Peptide Fragments/metabolism, Neurons/cytology/*metabolism, Antigens, CD15/genetics/*metabolism, Fucosyltransferases/genetics/*metabolism, Glycoproteins/*genetics/metabolism, Neural Cell Adhesion Molecules/metabolism, Neurites/metabolism/*pathology, Peptide Mapping, Sialic Acids/metabolism, Humans, Cells, Cultured, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Amino Acid Sequence, Molecular Sequence Data, Oligonucleotide Array Sequence Analysis, Blotting, Western, Immunoprecipitation, Down-Regulation, *Cell Differentiation, Glycosylation, Polysaccharides/*metabolism, Peptide Fragments/metabolism, Neurons/cytology/*metabolism, Antigens, CD15/genetics/*metabolism, Fucosyltransferases/genetics/*metabolism, Glycoproteins/*genetics/metabolism, Neural Cell Adhesion Molecules/metabolism, Neurites/metabolism/*pathology, Peptide Mapping, Sialic Acids/metabolism",
author = "Ricardo Gouveia and Lana Schaffer and Suzanne Papp and Nicolas Grammel and Sebastian Kandzia and Head, {Steven R} and Ralf Kleene and Melitta Schachner and Conradt, {Harald S} and J{\'u}lia Costa",
year = "2012",
language = "English",
volume = "1820",
pages = "2007--2019",
journal = "Biochim Biophys Acta",
issn = "0006-3002",
number = "12",

}

RIS

TY - JOUR

T1 - Expression of glycogenes in differentiating human NT2N neurons. Downregulation of fucosyltransferase 9 leads to decreased Lewis(x) levels and impaired neurite outgrowth.

AU - Gouveia, Ricardo

AU - Schaffer, Lana

AU - Papp, Suzanne

AU - Grammel, Nicolas

AU - Kandzia, Sebastian

AU - Head, Steven R

AU - Kleene, Ralf

AU - Schachner, Melitta

AU - Conradt, Harald S

AU - Costa, Júlia

PY - 2012

Y1 - 2012

N2 - Several glycan structures are functionally relevant in biological events associated with differentiation and regeneration which occur in the central nervous system. Here we have analysed the glycogene expression and glycosylation patterns during human NT2N neuron differentiation. We have further studied the impact of downregulating fucosyltransferase 9 (FUT9) on neurite outgrowth.

AB - Several glycan structures are functionally relevant in biological events associated with differentiation and regeneration which occur in the central nervous system. Here we have analysed the glycogene expression and glycosylation patterns during human NT2N neuron differentiation. We have further studied the impact of downregulating fucosyltransferase 9 (FUT9) on neurite outgrowth.

KW - Humans

KW - Cells, Cultured

KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

KW - Amino Acid Sequence

KW - Molecular Sequence Data

KW - Oligonucleotide Array Sequence Analysis

KW - Blotting, Western

KW - Immunoprecipitation

KW - Down-Regulation

KW - Cell Differentiation

KW - Glycosylation

KW - Polysaccharides/metabolism

KW - Peptide Fragments/metabolism

KW - Neurons/cytology/metabolism

KW - Antigens, CD15/genetics/metabolism

KW - Fucosyltransferases/genetics/metabolism

KW - Glycoproteins/genetics/metabolism

KW - Neural Cell Adhesion Molecules/metabolism

KW - Neurites/metabolism/pathology

KW - Peptide Mapping

KW - Sialic Acids/metabolism

KW - Humans

KW - Cells, Cultured

KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

KW - Amino Acid Sequence

KW - Molecular Sequence Data

KW - Oligonucleotide Array Sequence Analysis

KW - Blotting, Western

KW - Immunoprecipitation

KW - Down-Regulation

KW - Cell Differentiation

KW - Glycosylation

KW - Polysaccharides/metabolism

KW - Peptide Fragments/metabolism

KW - Neurons/cytology/metabolism

KW - Antigens, CD15/genetics/metabolism

KW - Fucosyltransferases/genetics/metabolism

KW - Glycoproteins/genetics/metabolism

KW - Neural Cell Adhesion Molecules/metabolism

KW - Neurites/metabolism/pathology

KW - Peptide Mapping

KW - Sialic Acids/metabolism

M3 - SCORING: Journal article

VL - 1820

SP - 2007

EP - 2019

JO - Biochim Biophys Acta

JF - Biochim Biophys Acta

SN - 0006-3002

IS - 12

M1 - 12

ER -