Experimental orthotopic tracheal transplantation: The Stanford technique

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Experimental orthotopic tracheal transplantation: The Stanford technique. / Schrepfer, Sonja; Deuse, Tobias; Hoyt, Grant; Sheikh, Ahmad Y; Hoffmann, Joerg; Reichenspurner, Hermann; Robbins, Robert C; Pelletier, Marc P.

In: MICROSURG, Vol. 27, No. 3, 2007, p. 187-189.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Schrepfer, S, Deuse, T, Hoyt, G, Sheikh, AY, Hoffmann, J, Reichenspurner, H, Robbins, RC & Pelletier, MP 2007, 'Experimental orthotopic tracheal transplantation: The Stanford technique', MICROSURG, vol. 27, no. 3, pp. 187-189. https://doi.org/10.1002/micr.20329

APA

Schrepfer, S., Deuse, T., Hoyt, G., Sheikh, A. Y., Hoffmann, J., Reichenspurner, H., Robbins, R. C., & Pelletier, M. P. (2007). Experimental orthotopic tracheal transplantation: The Stanford technique. MICROSURG, 27(3), 187-189. https://doi.org/10.1002/micr.20329

Vancouver

Bibtex

@article{59425e293d5d446fa9a04f0d3b24effd,
title = "Experimental orthotopic tracheal transplantation: The Stanford technique",
abstract = "The rat heterotopic tracheal transplantation model is widely used as an experimental model to study the development of obliterative airway disease (OAD) and to assess immunosuppressive strategies for chronic rejection. Despite its widespread application, the heterotopic transplantation model does have a number of limitations like the lack of air flow and mucociliary clearance. The present article provides a detailed description of the surgical technique for orthotopic tracheal transplantations, which may share more similarities with lung transplants in humans. The technique is easy to learn, the procedure is well tolerated by the animals, and the grafts develop OAD lesions similar to those of human obliterative bronchiolitis.",
keywords = "Animals, Models, Animal, Rats, Suture Techniques, Trachea/transplantation",
author = "Sonja Schrepfer and Tobias Deuse and Grant Hoyt and Sheikh, {Ahmad Y} and Joerg Hoffmann and Hermann Reichenspurner and Robbins, {Robert C} and Pelletier, {Marc P}",
note = "(c) 2007 Wiley-Liss, Inc.",
year = "2007",
doi = "10.1002/micr.20329",
language = "English",
volume = "27",
pages = "187--189",
journal = "MICROSURG",
issn = "0738-1085",
publisher = "Wiley-Liss Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Experimental orthotopic tracheal transplantation: The Stanford technique

AU - Schrepfer, Sonja

AU - Deuse, Tobias

AU - Hoyt, Grant

AU - Sheikh, Ahmad Y

AU - Hoffmann, Joerg

AU - Reichenspurner, Hermann

AU - Robbins, Robert C

AU - Pelletier, Marc P

N1 - (c) 2007 Wiley-Liss, Inc.

PY - 2007

Y1 - 2007

N2 - The rat heterotopic tracheal transplantation model is widely used as an experimental model to study the development of obliterative airway disease (OAD) and to assess immunosuppressive strategies for chronic rejection. Despite its widespread application, the heterotopic transplantation model does have a number of limitations like the lack of air flow and mucociliary clearance. The present article provides a detailed description of the surgical technique for orthotopic tracheal transplantations, which may share more similarities with lung transplants in humans. The technique is easy to learn, the procedure is well tolerated by the animals, and the grafts develop OAD lesions similar to those of human obliterative bronchiolitis.

AB - The rat heterotopic tracheal transplantation model is widely used as an experimental model to study the development of obliterative airway disease (OAD) and to assess immunosuppressive strategies for chronic rejection. Despite its widespread application, the heterotopic transplantation model does have a number of limitations like the lack of air flow and mucociliary clearance. The present article provides a detailed description of the surgical technique for orthotopic tracheal transplantations, which may share more similarities with lung transplants in humans. The technique is easy to learn, the procedure is well tolerated by the animals, and the grafts develop OAD lesions similar to those of human obliterative bronchiolitis.

KW - Animals

KW - Models, Animal

KW - Rats

KW - Suture Techniques

KW - Trachea/transplantation

U2 - 10.1002/micr.20329

DO - 10.1002/micr.20329

M3 - SCORING: Journal article

C2 - 17326196

VL - 27

SP - 187

EP - 189

JO - MICROSURG

JF - MICROSURG

SN - 0738-1085

IS - 3

ER -