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Estimating Disequilibrium Coefficients

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Estimating Disequilibrium Coefficients. / Vens, Maren; Ziegler, Andreas.

In: Methods Mol Biol, Vol. 1666, 2017, p. 117-132.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Vens, M & Ziegler, A 2017, 'Estimating Disequilibrium Coefficients', Methods Mol Biol, vol. 1666, pp. 117-132. https://doi.org/10.1007/978-1-4939-7274-6_7

APA

Vens, M., & Ziegler, A. (2017). Estimating Disequilibrium Coefficients. Methods Mol Biol, 1666, 117-132. https://doi.org/10.1007/978-1-4939-7274-6_7

Vancouver

Vens M, Ziegler A. Estimating Disequilibrium Coefficients. Methods Mol Biol. 2017;1666:117-132. https://doi.org/10.1007/978-1-4939-7274-6_7

Bibtex

@article{178d03bcde0747b7b7ee03c444b17c0f,
title = "Estimating Disequilibrium Coefficients",
abstract = "Gametic phase disequilibrium is the nonrandom association of alleles within gametes. Linkage disequilibrium (LD) describes the special case of deviation from independence between alleles at two linked genetic loci. Estimation of allelic LD requires knowledge of haplotypes. Genotype-based LD measures dispense with the haplotype estimation step and avoid bias in LD estimation. In this chapter, the most important measures for allelic and genotypic LD are introduced. The use of software packages for LD estimation is illustrated.",
keywords = "Journal Article",
author = "Maren Vens and Andreas Ziegler",
year = "2017",
doi = "10.1007/978-1-4939-7274-6_7",
language = "English",
volume = "1666",
pages = "117--132",
journal = "Methods Mol Biol",
issn = "1064-3745",
publisher = "Humana Press",

}

RIS

TY - JOUR

T1 - Estimating Disequilibrium Coefficients

AU - Vens, Maren

AU - Ziegler, Andreas

PY - 2017

Y1 - 2017

N2 - Gametic phase disequilibrium is the nonrandom association of alleles within gametes. Linkage disequilibrium (LD) describes the special case of deviation from independence between alleles at two linked genetic loci. Estimation of allelic LD requires knowledge of haplotypes. Genotype-based LD measures dispense with the haplotype estimation step and avoid bias in LD estimation. In this chapter, the most important measures for allelic and genotypic LD are introduced. The use of software packages for LD estimation is illustrated.

AB - Gametic phase disequilibrium is the nonrandom association of alleles within gametes. Linkage disequilibrium (LD) describes the special case of deviation from independence between alleles at two linked genetic loci. Estimation of allelic LD requires knowledge of haplotypes. Genotype-based LD measures dispense with the haplotype estimation step and avoid bias in LD estimation. In this chapter, the most important measures for allelic and genotypic LD are introduced. The use of software packages for LD estimation is illustrated.

KW - Journal Article

U2 - 10.1007/978-1-4939-7274-6_7

DO - 10.1007/978-1-4939-7274-6_7

M3 - SCORING: Journal article

C2 - 28980244

VL - 1666

SP - 117

EP - 132

JO - Methods Mol Biol

JF - Methods Mol Biol

SN - 1064-3745

ER -