Endocrine and immune substrates of depressive symptoms and fatigue in multiple sclerosis patients with comorbid major depression.
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Abstract
Depression and fatigue are among the most common symptoms of multiple sclerosis (MS). These symptoms frequently co-occur and partially overlap in MS but their underlying biological substrates are unclear. In this study, the relative role of cytokines and hypothalamic-pituitary-adrenal (HPA) axis activity in depression and fatigue were examined in patients with relapsing-remitting MS (RRMS).
Bibliographical data
| Original language | English |
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| Article number | 7 |
| ISSN | 0022-3050 |
| Publication status | Published - 2011 |
| pubmed | 21296901 |
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