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Embolus Retriever with Interlinked Cages versus other stent retrievers in acute ischemic stroke: an observational comparative study

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Embolus Retriever with Interlinked Cages versus other stent retrievers in acute ischemic stroke: an observational comparative study. / Gruber, Philipp; Zeller, Salome; Garcia-Esperon, Carlos; Berberat, Jatta; Anon, Javier; Diepers, Michael; Nedeltchev, Krassen; Flottmann, Fabian; Fiehler, Jens; Remonda, Luca; Kahles, Timo.

In: J NEUROINTERV SURG, Vol. 10, No. 12, 12.2018, p. e31.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Gruber, P, Zeller, S, Garcia-Esperon, C, Berberat, J, Anon, J, Diepers, M, Nedeltchev, K, Flottmann, F, Fiehler, J, Remonda, L & Kahles, T 2018, 'Embolus Retriever with Interlinked Cages versus other stent retrievers in acute ischemic stroke: an observational comparative study', J NEUROINTERV SURG, vol. 10, no. 12, pp. e31. https://doi.org/10.1136/neurintsurg-2018-013838

APA

Gruber, P., Zeller, S., Garcia-Esperon, C., Berberat, J., Anon, J., Diepers, M., Nedeltchev, K., Flottmann, F., Fiehler, J., Remonda, L., & Kahles, T. (2018). Embolus Retriever with Interlinked Cages versus other stent retrievers in acute ischemic stroke: an observational comparative study. J NEUROINTERV SURG, 10(12), e31. https://doi.org/10.1136/neurintsurg-2018-013838

Vancouver

Gruber P, Zeller S, Garcia-Esperon C, Berberat J, Anon J, Diepers M et al. Embolus Retriever with Interlinked Cages versus other stent retrievers in acute ischemic stroke: an observational comparative study. J NEUROINTERV SURG. 2018 Dec;10(12):e31. https://doi.org/10.1136/neurintsurg-2018-013838

Bibtex

@article{8a554fec3f994841a021f0eca569984e,
title = "Embolus Retriever with Interlinked Cages versus other stent retrievers in acute ischemic stroke: an observational comparative study",
abstract = "BACKGROUND AND PURPOSE: Given the promising performance of the new Embolus Retriever with Interlinked Cages (ERIC) in smaller case series, we sought to assess the efficacy and safety of mechanical thrombectomy (MT) with ERIC compared with other stent retrievers (SRs) in acute ischemic stroke due to large vessel occlusion (LVO).METHODS: We reviewed the databases of two comprehensive stroke centers in in Germany and Switzerland for MT due to LVO in the anterior circulation with either ERIC or another SR as a first device. Co-primary outcome was defined as successful recanalization (Thrombolysis in Cerebral Infarction 2b/3) after the first device and favorable outcome (modified Rankin Scale score 0-2) at 90 days' follow-up. Multiple logistic regression analysis was applied to adjust for potential confounders.RESULTS: 183 consecutive patients with stroke were treated with either ERIC (49%) or a SR (51%) as the first device and successful recanalization was seen in 82% and 57%, respectively (P<0.001). Adding SR to futile ERIC recanalization or vice versa increased final recanalization rates (ERIC: 87%, SR: 79%). The use of ERIC as a first device resulted in favorable clinical outcome in 50% compared with 35% when a SR was used (P=0.038), an effect driven by age, stroke severity, presence of carotid-T-occlusion, and general anesthesia and not by the device deployed.CONCLUSION: The use of ERIC as a first device appeared to be associated with higher rates of successful recanalization and resulted in better functional outcome. However, favorable outcome was not attributable to ERIC. Most importantly, both device types complemented one another and improved final recanalization rates when used successively.",
keywords = "Aged, Aged, 80 and over, Brain Ischemia, Device Removal, Embolism, Female, Humans, Male, Middle Aged, Retrospective Studies, Stents, Stroke, Thrombectomy, Treatment Outcome, Comparative Study, Journal Article, Multicenter Study, Observational Study",
author = "Philipp Gruber and Salome Zeller and Carlos Garcia-Esperon and Jatta Berberat and Javier Anon and Michael Diepers and Krassen Nedeltchev and Fabian Flottmann and Jens Fiehler and Luca Remonda and Timo Kahles",
note = "{\textcopyright} Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.",
year = "2018",
month = dec,
doi = "10.1136/neurintsurg-2018-013838",
language = "English",
volume = "10",
pages = "e31",
journal = "J NEUROINTERV SURG",
issn = "1759-8478",
publisher = "BMJ PUBLISHING GROUP",
number = "12",

}

RIS

TY - JOUR

T1 - Embolus Retriever with Interlinked Cages versus other stent retrievers in acute ischemic stroke: an observational comparative study

AU - Gruber, Philipp

AU - Zeller, Salome

AU - Garcia-Esperon, Carlos

AU - Berberat, Jatta

AU - Anon, Javier

AU - Diepers, Michael

AU - Nedeltchev, Krassen

AU - Flottmann, Fabian

AU - Fiehler, Jens

AU - Remonda, Luca

AU - Kahles, Timo

N1 - © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

PY - 2018/12

Y1 - 2018/12

N2 - BACKGROUND AND PURPOSE: Given the promising performance of the new Embolus Retriever with Interlinked Cages (ERIC) in smaller case series, we sought to assess the efficacy and safety of mechanical thrombectomy (MT) with ERIC compared with other stent retrievers (SRs) in acute ischemic stroke due to large vessel occlusion (LVO).METHODS: We reviewed the databases of two comprehensive stroke centers in in Germany and Switzerland for MT due to LVO in the anterior circulation with either ERIC or another SR as a first device. Co-primary outcome was defined as successful recanalization (Thrombolysis in Cerebral Infarction 2b/3) after the first device and favorable outcome (modified Rankin Scale score 0-2) at 90 days' follow-up. Multiple logistic regression analysis was applied to adjust for potential confounders.RESULTS: 183 consecutive patients with stroke were treated with either ERIC (49%) or a SR (51%) as the first device and successful recanalization was seen in 82% and 57%, respectively (P<0.001). Adding SR to futile ERIC recanalization or vice versa increased final recanalization rates (ERIC: 87%, SR: 79%). The use of ERIC as a first device resulted in favorable clinical outcome in 50% compared with 35% when a SR was used (P=0.038), an effect driven by age, stroke severity, presence of carotid-T-occlusion, and general anesthesia and not by the device deployed.CONCLUSION: The use of ERIC as a first device appeared to be associated with higher rates of successful recanalization and resulted in better functional outcome. However, favorable outcome was not attributable to ERIC. Most importantly, both device types complemented one another and improved final recanalization rates when used successively.

AB - BACKGROUND AND PURPOSE: Given the promising performance of the new Embolus Retriever with Interlinked Cages (ERIC) in smaller case series, we sought to assess the efficacy and safety of mechanical thrombectomy (MT) with ERIC compared with other stent retrievers (SRs) in acute ischemic stroke due to large vessel occlusion (LVO).METHODS: We reviewed the databases of two comprehensive stroke centers in in Germany and Switzerland for MT due to LVO in the anterior circulation with either ERIC or another SR as a first device. Co-primary outcome was defined as successful recanalization (Thrombolysis in Cerebral Infarction 2b/3) after the first device and favorable outcome (modified Rankin Scale score 0-2) at 90 days' follow-up. Multiple logistic regression analysis was applied to adjust for potential confounders.RESULTS: 183 consecutive patients with stroke were treated with either ERIC (49%) or a SR (51%) as the first device and successful recanalization was seen in 82% and 57%, respectively (P<0.001). Adding SR to futile ERIC recanalization or vice versa increased final recanalization rates (ERIC: 87%, SR: 79%). The use of ERIC as a first device resulted in favorable clinical outcome in 50% compared with 35% when a SR was used (P=0.038), an effect driven by age, stroke severity, presence of carotid-T-occlusion, and general anesthesia and not by the device deployed.CONCLUSION: The use of ERIC as a first device appeared to be associated with higher rates of successful recanalization and resulted in better functional outcome. However, favorable outcome was not attributable to ERIC. Most importantly, both device types complemented one another and improved final recanalization rates when used successively.

KW - Aged

KW - Aged, 80 and over

KW - Brain Ischemia

KW - Device Removal

KW - Embolism

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Retrospective Studies

KW - Stents

KW - Stroke

KW - Thrombectomy

KW - Treatment Outcome

KW - Comparative Study

KW - Journal Article

KW - Multicenter Study

KW - Observational Study

U2 - 10.1136/neurintsurg-2018-013838

DO - 10.1136/neurintsurg-2018-013838

M3 - SCORING: Journal article

C2 - 29773715

VL - 10

SP - e31

JO - J NEUROINTERV SURG

JF - J NEUROINTERV SURG

SN - 1759-8478

IS - 12

ER -