Effects of continuous and triggered atrial overdrive pacing on paroxysmal atrial fibrillation in pacemaker patients

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Effects of continuous and triggered atrial overdrive pacing on paroxysmal atrial fibrillation in pacemaker patients. / Schuchert, Andreas; Rebeski, Hans-Peter; Peiffer, Thomas; Bub, Eberhard; Dietz, Armin; Mortensen, Kai; Aydin, Mohammed Ali; Camm, John; Gazarek, Steffen; Meinertz, Thomas; 3:4 Study Group.

In: PACE, Vol. 31, No. 8, 08.2008, p. 929-934.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Schuchert, A, Rebeski, H-P, Peiffer, T, Bub, E, Dietz, A, Mortensen, K, Aydin, MA, Camm, J, Gazarek, S, Meinertz, T & 3:4 Study Group 2008, 'Effects of continuous and triggered atrial overdrive pacing on paroxysmal atrial fibrillation in pacemaker patients', PACE, vol. 31, no. 8, pp. 929-934. https://doi.org/10.1111/j.1540-8159.2008.01118.x

APA

Schuchert, A., Rebeski, H-P., Peiffer, T., Bub, E., Dietz, A., Mortensen, K., Aydin, M. A., Camm, J., Gazarek, S., Meinertz, T., & 3:4 Study Group (2008). Effects of continuous and triggered atrial overdrive pacing on paroxysmal atrial fibrillation in pacemaker patients. PACE, 31(8), 929-934. https://doi.org/10.1111/j.1540-8159.2008.01118.x

Vancouver

Bibtex

@article{54741978502e4bd48bf18c04de0b272c,
title = "Effects of continuous and triggered atrial overdrive pacing on paroxysmal atrial fibrillation in pacemaker patients",
abstract = "BACKGROUND: The aim of the study was to compare the effects of different pacing strategies to prevent paroxysmal atrial fibrillation (AF): triggered atrial overdrive pacing versus the combination of triggered and continuous overdrive pacing.METHODS: Patients with an indication for dual-chamber pacing (Selection 9000, Prevent AF; Vitatron B.V., Arnhem, the Netherlands) and a history of paroxysmal AF were randomized to triggered atrial pacing (three pacing functions, {"}triggered group{"}: PAC Suppression, Post-PAC Response, and Post-Exercise Response) or to the combination of continuous (Pace Conditioning) and triggered atrial pacing (four pacing functions, {"}combined group{"}). After 3 months, there was a crossover to the other pacemaker setting.RESULTS: In 171 enrolled patients, the median AF burden of the combined group was with 2.1% versus 0.1% in the triggered group (P = 0.014). Fewer AF episodes were observed in the triggered (median: 7) than in the combined group (median: 116; P = 0.016). The combined group had more frequent atrial pacing (median 97%) than the triggered group with 85% (P < 0.001), but ventricular pacing was not significantly different with 95% and 96% in the combined and triggered group, respectively. After the crossover, the AF burden increased in the triggered group to 0.3% and decreased in the combined group to 0.4%.CONCLUSIONS: Triggered atrial pacing functions alone resulted in a low AF burden. The additional activation of continuous atrial overdrive pacing increased the percentage of atrial pacing, but had no beneficial effects on the prevention of paroxysmal AF.",
keywords = "Aged, Atrial Fibrillation/epidemiology, Female, Germany/epidemiology, Humans, Incidence, Pacemaker, Artificial/statistics & numerical data, Risk Assessment/methods, Risk Factors",
author = "Andreas Schuchert and Hans-Peter Rebeski and Thomas Peiffer and Eberhard Bub and Armin Dietz and Kai Mortensen and Aydin, {Mohammed Ali} and John Camm and Steffen Gazarek and Thomas Meinertz and {3:4 Study Group}",
year = "2008",
month = aug,
doi = "10.1111/j.1540-8159.2008.01118.x",
language = "English",
volume = "31",
pages = "929--934",
journal = "PACE",
issn = "0147-8389",
publisher = "Wiley-Blackwell",
number = "8",

}

RIS

TY - JOUR

T1 - Effects of continuous and triggered atrial overdrive pacing on paroxysmal atrial fibrillation in pacemaker patients

AU - Schuchert, Andreas

AU - Rebeski, Hans-Peter

AU - Peiffer, Thomas

AU - Bub, Eberhard

AU - Dietz, Armin

AU - Mortensen, Kai

AU - Aydin, Mohammed Ali

AU - Camm, John

AU - Gazarek, Steffen

AU - Meinertz, Thomas

AU - 3:4 Study Group

PY - 2008/8

Y1 - 2008/8

N2 - BACKGROUND: The aim of the study was to compare the effects of different pacing strategies to prevent paroxysmal atrial fibrillation (AF): triggered atrial overdrive pacing versus the combination of triggered and continuous overdrive pacing.METHODS: Patients with an indication for dual-chamber pacing (Selection 9000, Prevent AF; Vitatron B.V., Arnhem, the Netherlands) and a history of paroxysmal AF were randomized to triggered atrial pacing (three pacing functions, "triggered group": PAC Suppression, Post-PAC Response, and Post-Exercise Response) or to the combination of continuous (Pace Conditioning) and triggered atrial pacing (four pacing functions, "combined group"). After 3 months, there was a crossover to the other pacemaker setting.RESULTS: In 171 enrolled patients, the median AF burden of the combined group was with 2.1% versus 0.1% in the triggered group (P = 0.014). Fewer AF episodes were observed in the triggered (median: 7) than in the combined group (median: 116; P = 0.016). The combined group had more frequent atrial pacing (median 97%) than the triggered group with 85% (P < 0.001), but ventricular pacing was not significantly different with 95% and 96% in the combined and triggered group, respectively. After the crossover, the AF burden increased in the triggered group to 0.3% and decreased in the combined group to 0.4%.CONCLUSIONS: Triggered atrial pacing functions alone resulted in a low AF burden. The additional activation of continuous atrial overdrive pacing increased the percentage of atrial pacing, but had no beneficial effects on the prevention of paroxysmal AF.

AB - BACKGROUND: The aim of the study was to compare the effects of different pacing strategies to prevent paroxysmal atrial fibrillation (AF): triggered atrial overdrive pacing versus the combination of triggered and continuous overdrive pacing.METHODS: Patients with an indication for dual-chamber pacing (Selection 9000, Prevent AF; Vitatron B.V., Arnhem, the Netherlands) and a history of paroxysmal AF were randomized to triggered atrial pacing (three pacing functions, "triggered group": PAC Suppression, Post-PAC Response, and Post-Exercise Response) or to the combination of continuous (Pace Conditioning) and triggered atrial pacing (four pacing functions, "combined group"). After 3 months, there was a crossover to the other pacemaker setting.RESULTS: In 171 enrolled patients, the median AF burden of the combined group was with 2.1% versus 0.1% in the triggered group (P = 0.014). Fewer AF episodes were observed in the triggered (median: 7) than in the combined group (median: 116; P = 0.016). The combined group had more frequent atrial pacing (median 97%) than the triggered group with 85% (P < 0.001), but ventricular pacing was not significantly different with 95% and 96% in the combined and triggered group, respectively. After the crossover, the AF burden increased in the triggered group to 0.3% and decreased in the combined group to 0.4%.CONCLUSIONS: Triggered atrial pacing functions alone resulted in a low AF burden. The additional activation of continuous atrial overdrive pacing increased the percentage of atrial pacing, but had no beneficial effects on the prevention of paroxysmal AF.

KW - Aged

KW - Atrial Fibrillation/epidemiology

KW - Female

KW - Germany/epidemiology

KW - Humans

KW - Incidence

KW - Pacemaker, Artificial/statistics & numerical data

KW - Risk Assessment/methods

KW - Risk Factors

U2 - 10.1111/j.1540-8159.2008.01118.x

DO - 10.1111/j.1540-8159.2008.01118.x

M3 - SCORING: Journal article

C2 - 18684247

VL - 31

SP - 929

EP - 934

JO - PACE

JF - PACE

SN - 0147-8389

IS - 8

ER -