Effectiveness of Integrated Care Including Therapeutic Assertive Community Treatment in Severe Schizophrenia Spectrum and Bipolar I Disorders: The 24-Month Follow-Up ACCESS II Study
Standard
Effectiveness of Integrated Care Including Therapeutic Assertive Community Treatment in Severe Schizophrenia Spectrum and Bipolar I Disorders: The 24-Month Follow-Up ACCESS II Study. / Schöttle, Daniel; Schimmelmann, Benno G; Karow, Anne; Ruppelt, Friederike; Sauerbier, Anne-Lena; Bussopulos-Orpin, Alexandra; Frieling, Marietta; Golks, Dietmar; Kerstan, Andrea; Nika, Evangelia; Schödlbauer, Michael; Daubmann, Anne; Wegscheider, Karl; Lange, Matthias; Ohm, Gunda; Lange, Benjamin; Meigel-Schleiff, Christina; Naber, Dieter; Wiedemann, Klaus; Bock, Thomas; Lambert, Martin.
In: J CLIN PSYCHIAT, Vol. 75, No. 12, 01.12.2014, p. 1371-1379.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Effectiveness of Integrated Care Including Therapeutic Assertive Community Treatment in Severe Schizophrenia Spectrum and Bipolar I Disorders: The 24-Month Follow-Up ACCESS II Study
AU - Schöttle, Daniel
AU - Schimmelmann, Benno G
AU - Karow, Anne
AU - Ruppelt, Friederike
AU - Sauerbier, Anne-Lena
AU - Bussopulos-Orpin, Alexandra
AU - Frieling, Marietta
AU - Golks, Dietmar
AU - Kerstan, Andrea
AU - Nika, Evangelia
AU - Schödlbauer, Michael
AU - Daubmann, Anne
AU - Wegscheider, Karl
AU - Lange, Matthias
AU - Ohm, Gunda
AU - Lange, Benjamin
AU - Meigel-Schleiff, Christina
AU - Naber, Dieter
AU - Wiedemann, Klaus
AU - Bock, Thomas
AU - Lambert, Martin
N1 - © Copyright 2014 Physicians Postgraduate Press, Inc.
PY - 2014/12/1
Y1 - 2014/12/1
N2 - OBJECTIVE: The ACCESS treatment model offers assertive community treatment embedded in an integrated care program to patients with psychoses. Compared to standard care and within a controlled study, it proved to be more effective in terms of service disengagement and illness outcomes in patients with schizophrenia spectrum disorders over 12 months. ACCESS was implemented into clinical routine and its effectiveness assessed over 24 months in severe schizophrenia spectrum disorders and bipolar I disorder with psychotic features (DSM-IV) in a cohort study.METHOD: All 115 patients treated in ACCESS (from May 2007 to October 2009) were included in the ACCESS II study. The primary outcome was rate of service disengagement. Secondary outcomes were change of psychopathology, severity of illness, psychosocial functioning, quality of life, satisfaction with care, medication nonadherence, length of hospital stay, and rates of involuntary hospitalization.RESULTS: Only 4 patients (3.4%) disengaged with the service. Another 11 (9.6%) left because they moved outside the catchment area. Patients received a mean of 1.6 outpatient contacts per week. Involuntary admissions decreased from 34.8% in the 2 previous years to 7.8% during ACCESS (P < .001). Mixed models repeated-measures analyses revealed significant improvements among all patients in psychopathology (effect size d = 0.64, P < .001), illness severity (d = 0.84, P = .03), functioning level (d = 0.65, P < .001), quality of life (d = 0.50, P < .001), and client satisfaction (d = 0.11, P < .001). At 24 months, 78.3% were fully adherent to medication, compared to 25.2% at baseline (P = .002).CONCLUSIONS: ACCESS was successfully implemented in clinical routine and maintained excellent rates of service engagement and other outcomes in patients with schizophrenia spectrum disorders or bipolar I disorder with psychotic features over 24 months.TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01888627.
AB - OBJECTIVE: The ACCESS treatment model offers assertive community treatment embedded in an integrated care program to patients with psychoses. Compared to standard care and within a controlled study, it proved to be more effective in terms of service disengagement and illness outcomes in patients with schizophrenia spectrum disorders over 12 months. ACCESS was implemented into clinical routine and its effectiveness assessed over 24 months in severe schizophrenia spectrum disorders and bipolar I disorder with psychotic features (DSM-IV) in a cohort study.METHOD: All 115 patients treated in ACCESS (from May 2007 to October 2009) were included in the ACCESS II study. The primary outcome was rate of service disengagement. Secondary outcomes were change of psychopathology, severity of illness, psychosocial functioning, quality of life, satisfaction with care, medication nonadherence, length of hospital stay, and rates of involuntary hospitalization.RESULTS: Only 4 patients (3.4%) disengaged with the service. Another 11 (9.6%) left because they moved outside the catchment area. Patients received a mean of 1.6 outpatient contacts per week. Involuntary admissions decreased from 34.8% in the 2 previous years to 7.8% during ACCESS (P < .001). Mixed models repeated-measures analyses revealed significant improvements among all patients in psychopathology (effect size d = 0.64, P < .001), illness severity (d = 0.84, P = .03), functioning level (d = 0.65, P < .001), quality of life (d = 0.50, P < .001), and client satisfaction (d = 0.11, P < .001). At 24 months, 78.3% were fully adherent to medication, compared to 25.2% at baseline (P = .002).CONCLUSIONS: ACCESS was successfully implemented in clinical routine and maintained excellent rates of service engagement and other outcomes in patients with schizophrenia spectrum disorders or bipolar I disorder with psychotic features over 24 months.TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01888627.
KW - Adolescent
KW - Adult
KW - Bipolar Disorder
KW - Community Mental Health Services
KW - Female
KW - Follow-Up Studies
KW - Humans
KW - Male
KW - Patient Satisfaction
KW - Quality of Life
KW - Schizophrenia
KW - Time Factors
KW - Treatment Outcome
KW - Young Adult
U2 - 10.4088/JCP.13m08817
DO - 10.4088/JCP.13m08817
M3 - SCORING: Journal article
C2 - 25188752
VL - 75
SP - 1371
EP - 1379
JO - J CLIN PSYCHIAT
JF - J CLIN PSYCHIAT
SN - 0160-6689
IS - 12
ER -