Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia.

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Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia. / Stams, [Unbekannt]; Wendy, A G; Den, Boer; Monique, L; Beverloo, [Unbekannt]; Berna, H; Kazemier, [Unbekannt]; Karin, M; Wering, van; Elisabeth, R; Janka-Schaub, Gritta; Gritta, E; Pieters, [Unbekannt]; Rob, [Unbekannt].

In: HAEMATOLOGICA, Vol. 90, No. 12, 12, 2005, p. 1697-1699.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Stams, U, Wendy, AG, Den, B, Monique, L, Beverloo, U, Berna, H, Kazemier, U, Karin, M, Wering, V, Elisabeth, R, Janka-Schaub, G, Gritta, E, Pieters, U & Rob, U 2005, 'Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia.', HAEMATOLOGICA, vol. 90, no. 12, 12, pp. 1697-1699. <http://www.ncbi.nlm.nih.gov/pubmed/16330447?dopt=Citation>

APA

Stams, U., Wendy, A. G., Den, B., Monique, L., Beverloo, U., Berna, H., Kazemier, U., Karin, M., Wering, V., Elisabeth, R., Janka-Schaub, G., Gritta, E., Pieters, U., & Rob, U. (2005). Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia. HAEMATOLOGICA, 90(12), 1697-1699. [12]. http://www.ncbi.nlm.nih.gov/pubmed/16330447?dopt=Citation

Vancouver

Bibtex

@article{ce75e81de4f341fab7c0fddefe501a88,
title = "Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia.",
abstract = "The fusion protein TEL-AML1 in t(12;21)+ acute lymphoblastic leukemia (ALL) recruits co-repressors and histone deacetylases (HDAC), which transrepress AML1 target genes. Normal bone marrow cells were more resistant to HDAC inhibitor FK228 induced cell killing than were cells from ALL patients with or without t(12;21). FK228 induced differentiation in ALL, irrespective of the presence of t(12;21).",
author = "[Unbekannt] Stams and Wendy, {A G} and Boer Den and L Monique and [Unbekannt] Beverloo and H Berna and [Unbekannt] Kazemier and M Karin and van Wering and R Elisabeth and Gritta Janka-Schaub and E Gritta and [Unbekannt] Pieters and [Unbekannt] Rob",
year = "2005",
language = "Deutsch",
volume = "90",
pages = "1697--1699",
journal = "HAEMATOLOGICA",
issn = "0390-6078",
publisher = "Ferrata Storti Foundation",
number = "12",

}

RIS

TY - JOUR

T1 - Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia.

AU - Stams, [Unbekannt]

AU - Wendy, A G

AU - Den, Boer

AU - Monique, L

AU - Beverloo, [Unbekannt]

AU - Berna, H

AU - Kazemier, [Unbekannt]

AU - Karin, M

AU - Wering, van

AU - Elisabeth, R

AU - Janka-Schaub, Gritta

AU - Gritta, E

AU - Pieters, [Unbekannt]

AU - Rob, [Unbekannt]

PY - 2005

Y1 - 2005

N2 - The fusion protein TEL-AML1 in t(12;21)+ acute lymphoblastic leukemia (ALL) recruits co-repressors and histone deacetylases (HDAC), which transrepress AML1 target genes. Normal bone marrow cells were more resistant to HDAC inhibitor FK228 induced cell killing than were cells from ALL patients with or without t(12;21). FK228 induced differentiation in ALL, irrespective of the presence of t(12;21).

AB - The fusion protein TEL-AML1 in t(12;21)+ acute lymphoblastic leukemia (ALL) recruits co-repressors and histone deacetylases (HDAC), which transrepress AML1 target genes. Normal bone marrow cells were more resistant to HDAC inhibitor FK228 induced cell killing than were cells from ALL patients with or without t(12;21). FK228 induced differentiation in ALL, irrespective of the presence of t(12;21).

M3 - SCORING: Zeitschriftenaufsatz

VL - 90

SP - 1697

EP - 1699

JO - HAEMATOLOGICA

JF - HAEMATOLOGICA

SN - 0390-6078

IS - 12

M1 - 12

ER -