Dynamics of the interaction of γδ T cells with their neighbors in vivo

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Dynamics of the interaction of γδ T cells with their neighbors in vivo. / Prinz, Immo.

In: CELL MOL LIFE SCI, Vol. 68, No. 14, 07.2011, p. 2391-8.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{a255c1eb46cb4ba1acf3eb18722cfe25,
title = "Dynamics of the interaction of γδ T cells with their neighbors in vivo",
abstract = "γδ T cells are a diverse component of the immune system in humans and mice with presumably important but still largely unknown functions. Understanding the dynamic interaction of γδ T cells with their neighbors should help to understand their physiological role. This review addresses recent advances and strategies to visualize the dynamic interactions of γδ T cells with their neighbors in vivo. Current knowledge regarding the dynamic contacts of tissue resident γδ T cells and epithelial cells, but also of the communication between circulating γδ T cells and DCs, monocytes and FoxP3(+) regulatory T cells is revisited with emphasis on the role of γδ T cell motility.",
keywords = "Animals, Cell Communication/immunology, Dendritic Cells/immunology, Green Fluorescent Proteins/genetics, Humans, Mice, Microscopy, Confocal/methods, Microscopy, Fluorescence, Multiphoton/methods, Receptors, Antigen, T-Cell, gamma-delta/genetics, T-Lymphocytes/immunology, T-Lymphocytes, Regulatory/immunology",
author = "Immo Prinz",
year = "2011",
month = jul,
doi = "10.1007/s00018-011-0701-y",
language = "English",
volume = "68",
pages = "2391--8",
journal = "CELL MOL LIFE SCI",
issn = "1420-682X",
publisher = "Birkhauser Verlag Basel",
number = "14",

}

RIS

TY - JOUR

T1 - Dynamics of the interaction of γδ T cells with their neighbors in vivo

AU - Prinz, Immo

PY - 2011/7

Y1 - 2011/7

N2 - γδ T cells are a diverse component of the immune system in humans and mice with presumably important but still largely unknown functions. Understanding the dynamic interaction of γδ T cells with their neighbors should help to understand their physiological role. This review addresses recent advances and strategies to visualize the dynamic interactions of γδ T cells with their neighbors in vivo. Current knowledge regarding the dynamic contacts of tissue resident γδ T cells and epithelial cells, but also of the communication between circulating γδ T cells and DCs, monocytes and FoxP3(+) regulatory T cells is revisited with emphasis on the role of γδ T cell motility.

AB - γδ T cells are a diverse component of the immune system in humans and mice with presumably important but still largely unknown functions. Understanding the dynamic interaction of γδ T cells with their neighbors should help to understand their physiological role. This review addresses recent advances and strategies to visualize the dynamic interactions of γδ T cells with their neighbors in vivo. Current knowledge regarding the dynamic contacts of tissue resident γδ T cells and epithelial cells, but also of the communication between circulating γδ T cells and DCs, monocytes and FoxP3(+) regulatory T cells is revisited with emphasis on the role of γδ T cell motility.

KW - Animals

KW - Cell Communication/immunology

KW - Dendritic Cells/immunology

KW - Green Fluorescent Proteins/genetics

KW - Humans

KW - Mice

KW - Microscopy, Confocal/methods

KW - Microscopy, Fluorescence, Multiphoton/methods

KW - Receptors, Antigen, T-Cell, gamma-delta/genetics

KW - T-Lymphocytes/immunology

KW - T-Lymphocytes, Regulatory/immunology

U2 - 10.1007/s00018-011-0701-y

DO - 10.1007/s00018-011-0701-y

M3 - SCORING: Review article

C2 - 21584813

VL - 68

SP - 2391

EP - 2398

JO - CELL MOL LIFE SCI

JF - CELL MOL LIFE SCI

SN - 1420-682X

IS - 14

ER -