Does the Dermatology Life Quality Index (DLQI) underestimate the disease-specific burden of psoriasis patients?
Standard
Does the Dermatology Life Quality Index (DLQI) underestimate the disease-specific burden of psoriasis patients? / Langenbruch, A; Radtke, M A; Gutknecht, M; Augustin, M.
In: J EUR ACAD DERMATOL, Vol. 33, No. 1, 01.2019, p. 123-127.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Does the Dermatology Life Quality Index (DLQI) underestimate the disease-specific burden of psoriasis patients?
AU - Langenbruch, A
AU - Radtke, M A
AU - Gutknecht, M
AU - Augustin, M
N1 - © 2018 European Academy of Dermatology and Venereology.
PY - 2019/1
Y1 - 2019/1
N2 - BACKGROUND: The Dermatology Life Quality Index (DLQI) is the most frequently used health-related quality of life (HRQoL) instrument for skin diseases. According to the DLQI instructions, the responses 'not relevant' and 'my skin problem has not at all affected this aspect of life' ('not at all') have to be scored as 0 = no HRQoL impairments.OBJECTIVE: The aim of this study was to estimate potential bias of DLQI measurements for patients with psoriasis based on items considered to be not relevant.METHODS: One thousand two hundred forty-three patients with psoriasis were surveyed in a cross-sectional study. Disease severity (Psoriasis Area and Severity Index, PASI) and subjective health state (EuroQoL Visual Analogue Scale, EQ VAS) were compared per DLQI item between patients who answered the respective question 'not relevant' and those who answered 'not at all'.RESULTS: Patients who declared a DLQI item to be not relevant showed a higher disease severity and a lower health state.CONCLUSION: Results indicate that patients who declare a DLQI item to be not relevant have a higher disease-related burden than those who do not feel affected by their psoriasis in the same aspect of life. If aspects of life are considered to be not relevant due to high disease burden, this should be reflected by a HRQoL instrument.
AB - BACKGROUND: The Dermatology Life Quality Index (DLQI) is the most frequently used health-related quality of life (HRQoL) instrument for skin diseases. According to the DLQI instructions, the responses 'not relevant' and 'my skin problem has not at all affected this aspect of life' ('not at all') have to be scored as 0 = no HRQoL impairments.OBJECTIVE: The aim of this study was to estimate potential bias of DLQI measurements for patients with psoriasis based on items considered to be not relevant.METHODS: One thousand two hundred forty-three patients with psoriasis were surveyed in a cross-sectional study. Disease severity (Psoriasis Area and Severity Index, PASI) and subjective health state (EuroQoL Visual Analogue Scale, EQ VAS) were compared per DLQI item between patients who answered the respective question 'not relevant' and those who answered 'not at all'.RESULTS: Patients who declared a DLQI item to be not relevant showed a higher disease severity and a lower health state.CONCLUSION: Results indicate that patients who declare a DLQI item to be not relevant have a higher disease-related burden than those who do not feel affected by their psoriasis in the same aspect of life. If aspects of life are considered to be not relevant due to high disease burden, this should be reflected by a HRQoL instrument.
KW - Journal Article
KW - Severity of Illness Index
KW - Cross-Sectional Studies
KW - Bias
KW - Humans
KW - Middle Aged
KW - Cost of Illness
KW - Male
KW - Quality of Life
KW - Adult
KW - Female
KW - Psoriasis/psychology
KW - Surveys and Questionnaires
KW - Aged
KW - Health Status
U2 - 10.1111/jdv.15226
DO - 10.1111/jdv.15226
M3 - SCORING: Journal article
C2 - 30160802
VL - 33
SP - 123
EP - 127
JO - J EUR ACAD DERMATOL
JF - J EUR ACAD DERMATOL
SN - 0926-9959
IS - 1
ER -