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DNA damage by X-rays and their impact on replication processes.

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DNA damage by X-rays and their impact on replication processes. / Parplys, Ann Christin; Petermann, Eva; Petersen, Cordula; Dikomey, Ekkehard; Borgmann, Kerstin.

In: RADIOTHER ONCOL, Vol. 102, No. 3, 3, 2012, p. 466-471.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Parplys, AC, Petermann, E, Petersen, C, Dikomey, E & Borgmann, K 2012, 'DNA damage by X-rays and their impact on replication processes.', RADIOTHER ONCOL, vol. 102, no. 3, 3, pp. 466-471. <http://www.ncbi.nlm.nih.gov/pubmed/22326574?dopt=Citation>

APA

Parplys, A. C., Petermann, E., Petersen, C., Dikomey, E., & Borgmann, K. (2012). DNA damage by X-rays and their impact on replication processes. RADIOTHER ONCOL, 102(3), 466-471. [3]. http://www.ncbi.nlm.nih.gov/pubmed/22326574?dopt=Citation

Vancouver

Parplys AC, Petermann E, Petersen C, Dikomey E, Borgmann K. DNA damage by X-rays and their impact on replication processes. RADIOTHER ONCOL. 2012;102(3):466-471. 3.

Bibtex

@article{495754d9b1dd4cf2af568c8722332bd9,
title = "DNA damage by X-rays and their impact on replication processes.",
abstract = "Replication-dependent radiosensitization of tumors ranks among the most promising tools for future improvements in tumor therapy. However, cell cycle checkpoint signaling during S phase is a key for maintaining genomic stability after ionizing irradiation allowing DNA damage repair by stabilizing replication forks, inhibiting new origin firing and recruiting DNA repair proteins. As the impact of the different types of DNA damage induced by ionizing radiation on replication fork functionality has not been investigated, this study was performed in tumor cells treated with various agents that induce specific DNA lesions.",
author = "Parplys, {Ann Christin} and Eva Petermann and Cordula Petersen and Ekkehard Dikomey and Kerstin Borgmann",
year = "2012",
language = "English",
volume = "102",
pages = "466--471",
journal = "RADIOTHER ONCOL",
issn = "0167-8140",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - DNA damage by X-rays and their impact on replication processes.

AU - Parplys, Ann Christin

AU - Petermann, Eva

AU - Petersen, Cordula

AU - Dikomey, Ekkehard

AU - Borgmann, Kerstin

PY - 2012

Y1 - 2012

N2 - Replication-dependent radiosensitization of tumors ranks among the most promising tools for future improvements in tumor therapy. However, cell cycle checkpoint signaling during S phase is a key for maintaining genomic stability after ionizing irradiation allowing DNA damage repair by stabilizing replication forks, inhibiting new origin firing and recruiting DNA repair proteins. As the impact of the different types of DNA damage induced by ionizing radiation on replication fork functionality has not been investigated, this study was performed in tumor cells treated with various agents that induce specific DNA lesions.

AB - Replication-dependent radiosensitization of tumors ranks among the most promising tools for future improvements in tumor therapy. However, cell cycle checkpoint signaling during S phase is a key for maintaining genomic stability after ionizing irradiation allowing DNA damage repair by stabilizing replication forks, inhibiting new origin firing and recruiting DNA repair proteins. As the impact of the different types of DNA damage induced by ionizing radiation on replication fork functionality has not been investigated, this study was performed in tumor cells treated with various agents that induce specific DNA lesions.

M3 - SCORING: Journal article

VL - 102

SP - 466

EP - 471

JO - RADIOTHER ONCOL

JF - RADIOTHER ONCOL

SN - 0167-8140

IS - 3

M1 - 3

ER -