Discrepant results of different tests for antibodies to hepatitis C in children with malignant diseases and in patients on renal replacement therapy

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Discrepant results of different tests for antibodies to hepatitis C in children with malignant diseases and in patients on renal replacement therapy. / Rautenberg, P; Schneppenheim, R; Leimenstoll, G; Behnke, H; Loose, G.

In: EUR J CLIN MICROBIOL, Vol. 10, No. 11, 01.11.1991, p. 978-81.

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@article{b2152d37864844928882cfd0a98ec0e5,
title = "Discrepant results of different tests for antibodies to hepatitis C in children with malignant diseases and in patients on renal replacement therapy",
abstract = "The serostatus of hepatitis C in pediatric oncological patients and in individuals on renal replacement therapy was tested for circulating antibodies to the c100-3 recombinant antigen of hepatitis C. Upon prescreening, 12 of 82 patients in the pediatric oncological group, 6 of 108 renal transplant recipients, and 17 of 150 patients on chronic intermittent hemodialysis were repeatedly positive. Further testing of these 35 sera by supplemental test assays revealed conflicting data, mostly in the pediatric oncological group and in renal transplant recipients. Only in 10 sera were identical results obtained, suggesting that positive test results in some groups at risk have only a low predictive value.",
keywords = "Antigens, Viral, Blood Transfusion, Child, Child, Preschool, Hepacivirus, Hepatitis Antibodies, Hepatitis C, Hepatitis C Antibodies, Humans, Immunoenzyme Techniques, Kidney Transplantation, Neoplasms, Predictive Value of Tests, Renal Dialysis, Viral Nonstructural Proteins",
author = "P Rautenberg and R Schneppenheim and G Leimenstoll and H Behnke and G Loose",
year = "1991",
month = nov,
day = "1",
language = "English",
volume = "10",
pages = "978--81",
journal = "EUR J CLIN MICROBIOL",
issn = "0934-9723",
publisher = "Springer",
number = "11",

}

RIS

TY - JOUR

T1 - Discrepant results of different tests for antibodies to hepatitis C in children with malignant diseases and in patients on renal replacement therapy

AU - Rautenberg, P

AU - Schneppenheim, R

AU - Leimenstoll, G

AU - Behnke, H

AU - Loose, G

PY - 1991/11/1

Y1 - 1991/11/1

N2 - The serostatus of hepatitis C in pediatric oncological patients and in individuals on renal replacement therapy was tested for circulating antibodies to the c100-3 recombinant antigen of hepatitis C. Upon prescreening, 12 of 82 patients in the pediatric oncological group, 6 of 108 renal transplant recipients, and 17 of 150 patients on chronic intermittent hemodialysis were repeatedly positive. Further testing of these 35 sera by supplemental test assays revealed conflicting data, mostly in the pediatric oncological group and in renal transplant recipients. Only in 10 sera were identical results obtained, suggesting that positive test results in some groups at risk have only a low predictive value.

AB - The serostatus of hepatitis C in pediatric oncological patients and in individuals on renal replacement therapy was tested for circulating antibodies to the c100-3 recombinant antigen of hepatitis C. Upon prescreening, 12 of 82 patients in the pediatric oncological group, 6 of 108 renal transplant recipients, and 17 of 150 patients on chronic intermittent hemodialysis were repeatedly positive. Further testing of these 35 sera by supplemental test assays revealed conflicting data, mostly in the pediatric oncological group and in renal transplant recipients. Only in 10 sera were identical results obtained, suggesting that positive test results in some groups at risk have only a low predictive value.

KW - Antigens, Viral

KW - Blood Transfusion

KW - Child

KW - Child, Preschool

KW - Hepacivirus

KW - Hepatitis Antibodies

KW - Hepatitis C

KW - Hepatitis C Antibodies

KW - Humans

KW - Immunoenzyme Techniques

KW - Kidney Transplantation

KW - Neoplasms

KW - Predictive Value of Tests

KW - Renal Dialysis

KW - Viral Nonstructural Proteins

M3 - SCORING: Journal article

C2 - 1724423

VL - 10

SP - 978

EP - 981

JO - EUR J CLIN MICROBIOL

JF - EUR J CLIN MICROBIOL

SN - 0934-9723

IS - 11

ER -