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Differences in clinical manifestations of imported versus autochthonous leptospirosis in Austria and Germany.

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Differences in clinical manifestations of imported versus autochthonous leptospirosis in Austria and Germany. / Hoffmeister, Bodo; Peyerl-Hoffmann, Gabriele; Pischke, Sven; Zollner-Schwetz, Ines; Krause, Robert; Müller, Matthias C; Graf, Angelika; Kluge, Stefan; Burchard, Gerd-Dieter; Kern, Winfried V; Suttorp, Norbert; Cramer, Jakob.

In: AM J TROP MED HYG, Vol. 83, No. 2, 2, 2010, p. 326-335.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Hoffmeister, B, Peyerl-Hoffmann, G, Pischke, S, Zollner-Schwetz, I, Krause, R, Müller, MC, Graf, A, Kluge, S, Burchard, G-D, Kern, WV, Suttorp, N & Cramer, J 2010, 'Differences in clinical manifestations of imported versus autochthonous leptospirosis in Austria and Germany.', AM J TROP MED HYG, vol. 83, no. 2, 2, pp. 326-335. <http://www.ncbi.nlm.nih.gov/pubmed/20682876?dopt=Citation>

APA

Hoffmeister, B., Peyerl-Hoffmann, G., Pischke, S., Zollner-Schwetz, I., Krause, R., Müller, M. C., Graf, A., Kluge, S., Burchard, G-D., Kern, W. V., Suttorp, N., & Cramer, J. (2010). Differences in clinical manifestations of imported versus autochthonous leptospirosis in Austria and Germany. AM J TROP MED HYG, 83(2), 326-335. [2]. http://www.ncbi.nlm.nih.gov/pubmed/20682876?dopt=Citation

Vancouver

Hoffmeister B, Peyerl-Hoffmann G, Pischke S, Zollner-Schwetz I, Krause R, Müller MC et al. Differences in clinical manifestations of imported versus autochthonous leptospirosis in Austria and Germany. AM J TROP MED HYG. 2010;83(2):326-335. 2.

Bibtex

@article{0c4bc3487d784c1b99ec1cf8595604a1,
title = "Differences in clinical manifestations of imported versus autochthonous leptospirosis in Austria and Germany.",
abstract = "Leptospirosis, a zoonosis occurring worldwide, has a broad spectrum of clinical manifestations. Recently, various countries observed an increase of severe anicteric cases. In Austria and Germany, growing numbers of imported cases are notified in addition to autochthonous infections. The aim of this study was to assess whether imported and autochthonous cases differ in clinical manifestations and outcome. We retrospectively analyzed 24 imported and 35 autochthonous cases treated in six infectious disease units between 1998 and 2008. To compare disease severity, patients were classified according to established independent risk factors for fatal outcome. Although severe leptospirosis (i.e., presence of > or = 1 independent risk factors for death) occurred in similar proportions of imported (67%) and autochthonous (86%) infections (P = 0.1), imported cases were significantly fewer icteric (13% versus 69%; P <0.0001). In conclusion, an increasing incidence of severe anicteric imported cases of leptospirosis should be anticipated with rising global travel activities.",
author = "Bodo Hoffmeister and Gabriele Peyerl-Hoffmann and Sven Pischke and Ines Zollner-Schwetz and Robert Krause and M{\"u}ller, {Matthias C} and Angelika Graf and Stefan Kluge and Gerd-Dieter Burchard and Kern, {Winfried V} and Norbert Suttorp and Jakob Cramer",
year = "2010",
language = "Deutsch",
volume = "83",
pages = "326--335",
journal = "AM J TROP MED HYG",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "2",

}

RIS

TY - JOUR

T1 - Differences in clinical manifestations of imported versus autochthonous leptospirosis in Austria and Germany.

AU - Hoffmeister, Bodo

AU - Peyerl-Hoffmann, Gabriele

AU - Pischke, Sven

AU - Zollner-Schwetz, Ines

AU - Krause, Robert

AU - Müller, Matthias C

AU - Graf, Angelika

AU - Kluge, Stefan

AU - Burchard, Gerd-Dieter

AU - Kern, Winfried V

AU - Suttorp, Norbert

AU - Cramer, Jakob

PY - 2010

Y1 - 2010

N2 - Leptospirosis, a zoonosis occurring worldwide, has a broad spectrum of clinical manifestations. Recently, various countries observed an increase of severe anicteric cases. In Austria and Germany, growing numbers of imported cases are notified in addition to autochthonous infections. The aim of this study was to assess whether imported and autochthonous cases differ in clinical manifestations and outcome. We retrospectively analyzed 24 imported and 35 autochthonous cases treated in six infectious disease units between 1998 and 2008. To compare disease severity, patients were classified according to established independent risk factors for fatal outcome. Although severe leptospirosis (i.e., presence of > or = 1 independent risk factors for death) occurred in similar proportions of imported (67%) and autochthonous (86%) infections (P = 0.1), imported cases were significantly fewer icteric (13% versus 69%; P <0.0001). In conclusion, an increasing incidence of severe anicteric imported cases of leptospirosis should be anticipated with rising global travel activities.

AB - Leptospirosis, a zoonosis occurring worldwide, has a broad spectrum of clinical manifestations. Recently, various countries observed an increase of severe anicteric cases. In Austria and Germany, growing numbers of imported cases are notified in addition to autochthonous infections. The aim of this study was to assess whether imported and autochthonous cases differ in clinical manifestations and outcome. We retrospectively analyzed 24 imported and 35 autochthonous cases treated in six infectious disease units between 1998 and 2008. To compare disease severity, patients were classified according to established independent risk factors for fatal outcome. Although severe leptospirosis (i.e., presence of > or = 1 independent risk factors for death) occurred in similar proportions of imported (67%) and autochthonous (86%) infections (P = 0.1), imported cases were significantly fewer icteric (13% versus 69%; P <0.0001). In conclusion, an increasing incidence of severe anicteric imported cases of leptospirosis should be anticipated with rising global travel activities.

M3 - SCORING: Zeitschriftenaufsatz

VL - 83

SP - 326

EP - 335

JO - AM J TROP MED HYG

JF - AM J TROP MED HYG

SN - 0002-9637

IS - 2

M1 - 2

ER -