Die primär sklerosierende Cholangitis als Präkanzerose

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Die primär sklerosierende Cholangitis als Präkanzerose. / Schramm, C; Galle, P R.

In: Z GASTROENTEROL, Vol. 43, No. 6, 06.2005, p. 607-11.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{4178fe835d404048923208f22b955f34,
title = "Die prim{\"a}r sklerosierende Cholangitis als Pr{\"a}kanzerose",
abstract = "Primary sclerosing cholangitis is a chronic cholestatic liver disease of unknown aetiology. The course of the disease is usually progressive with the development of liver cirrhosis leading to death or liver transplantation within an average of 12 years. To date it is well known that the development of hepatobiliary malignancies and the rate of colonic mucosal dysplasia and carcinoma in patients with concomitant ulcerative colitis are greatly enhanced in patients with PSC. PSC can therefore be regarded as a premalignant condition. The following review will focus on the development of cholangiocellular carcinoma in patients with PSC and the associated diagnostic and therapeutic challenges.",
keywords = "Biliary Tract Neoplasms, Biomarkers, Tumor, CA-19-9 Antigen, Cholangitis, Sclerosing, Humans, Liver Neoplasms, Precancerous Conditions, Risk Assessment, English Abstract, Journal Article, Review",
author = "C Schramm and Galle, {P R}",
year = "2005",
month = jun,
doi = "10.1055/s-2005-858311",
language = "Deutsch",
volume = "43",
pages = "607--11",
journal = "Z GASTROENTEROL",
issn = "0044-2771",
publisher = "Karl Demeter Verlag GmbH",
number = "6",

}

RIS

TY - JOUR

T1 - Die primär sklerosierende Cholangitis als Präkanzerose

AU - Schramm, C

AU - Galle, P R

PY - 2005/6

Y1 - 2005/6

N2 - Primary sclerosing cholangitis is a chronic cholestatic liver disease of unknown aetiology. The course of the disease is usually progressive with the development of liver cirrhosis leading to death or liver transplantation within an average of 12 years. To date it is well known that the development of hepatobiliary malignancies and the rate of colonic mucosal dysplasia and carcinoma in patients with concomitant ulcerative colitis are greatly enhanced in patients with PSC. PSC can therefore be regarded as a premalignant condition. The following review will focus on the development of cholangiocellular carcinoma in patients with PSC and the associated diagnostic and therapeutic challenges.

AB - Primary sclerosing cholangitis is a chronic cholestatic liver disease of unknown aetiology. The course of the disease is usually progressive with the development of liver cirrhosis leading to death or liver transplantation within an average of 12 years. To date it is well known that the development of hepatobiliary malignancies and the rate of colonic mucosal dysplasia and carcinoma in patients with concomitant ulcerative colitis are greatly enhanced in patients with PSC. PSC can therefore be regarded as a premalignant condition. The following review will focus on the development of cholangiocellular carcinoma in patients with PSC and the associated diagnostic and therapeutic challenges.

KW - Biliary Tract Neoplasms

KW - Biomarkers, Tumor

KW - CA-19-9 Antigen

KW - Cholangitis, Sclerosing

KW - Humans

KW - Liver Neoplasms

KW - Precancerous Conditions

KW - Risk Assessment

KW - English Abstract

KW - Journal Article

KW - Review

U2 - 10.1055/s-2005-858311

DO - 10.1055/s-2005-858311

M3 - SCORING: Review

C2 - 15986292

VL - 43

SP - 607

EP - 611

JO - Z GASTROENTEROL

JF - Z GASTROENTEROL

SN - 0044-2771

IS - 6

ER -