Diagnostic and Therapeutic Pathways of Intramuscular Myxoma

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Diagnostic and Therapeutic Pathways of Intramuscular Myxoma. / Reiter, Alonja; Trumm, Katharina; Ballhause, Tobias Malte; Weiß, Sebastian; Frosch, Karl-Heinz; Korthaus, Alexander; Bechler, Ulrich; Duprée, Anna; Luebke, Andreas M.; Bannas, Peter; Schlickewei, Carsten; Priemel, Matthias.

In: DIAGNOSTICS, Vol. 12, No. 7, 1573, 28.06.2022.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{e56bd8cf1516415eb2597faa6235a625,
title = "Diagnostic and Therapeutic Pathways of Intramuscular Myxoma",
abstract = "Intramuscular myxomas (IMMs) are benign tumors. Evidence regarding diagnostic and therapeutic pathways is rare, and guidelines do not exist due to their low incidence. The aim of this study was a retrospective analysis at a university cancer center and the interdisciplinary re-evaluation of the individual diagnostic and therapeutic procedures. Overall, 38 patients were included in the study. IMMs occurred mostly in middle-aged women. At the time of first consultation, 57.9% had few symptoms or were asymptomatic. In 92.1% of the cases, the tumor was localized in the extremities. The lower extremity was affected in 73.7%. The average size of IMMs was 5.0 cm. The proximally located tumors in the gluteus, thighs, and upper arms were significantly larger (p = 0.02) than the distally-located tumors in the forearms and lower legs. An MRI was performed in 97.4%. Based on imaging, an IMM was suspected in 5.6% by radiologists and in 54.1% by musculoskeletal surgeons. An incision biopsy was performed in 68.4% and led in 100.0% to the right histopathological diagnosis. In total, 89.5% of IMMs were resected. Postoperative complications requiring revision occurred in 8.8%. Recurrences or degenerations of IMMs were not reported in any of these cases.",
author = "Alonja Reiter and Katharina Trumm and Ballhause, {Tobias Malte} and Sebastian Wei{\ss} and Karl-Heinz Frosch and Alexander Korthaus and Ulrich Bechler and Anna Dupr{\'e}e and Luebke, {Andreas M.} and Peter Bannas and Carsten Schlickewei and Matthias Priemel",
year = "2022",
month = jun,
day = "28",
doi = "10.3390/diagnostics12071573",
language = "English",
volume = "12",
journal = "DIAGNOSTICS",
issn = "2075-4418",
publisher = "MDPI AG",
number = "7",

}

RIS

TY - JOUR

T1 - Diagnostic and Therapeutic Pathways of Intramuscular Myxoma

AU - Reiter, Alonja

AU - Trumm, Katharina

AU - Ballhause, Tobias Malte

AU - Weiß, Sebastian

AU - Frosch, Karl-Heinz

AU - Korthaus, Alexander

AU - Bechler, Ulrich

AU - Duprée, Anna

AU - Luebke, Andreas M.

AU - Bannas, Peter

AU - Schlickewei, Carsten

AU - Priemel, Matthias

PY - 2022/6/28

Y1 - 2022/6/28

N2 - Intramuscular myxomas (IMMs) are benign tumors. Evidence regarding diagnostic and therapeutic pathways is rare, and guidelines do not exist due to their low incidence. The aim of this study was a retrospective analysis at a university cancer center and the interdisciplinary re-evaluation of the individual diagnostic and therapeutic procedures. Overall, 38 patients were included in the study. IMMs occurred mostly in middle-aged women. At the time of first consultation, 57.9% had few symptoms or were asymptomatic. In 92.1% of the cases, the tumor was localized in the extremities. The lower extremity was affected in 73.7%. The average size of IMMs was 5.0 cm. The proximally located tumors in the gluteus, thighs, and upper arms were significantly larger (p = 0.02) than the distally-located tumors in the forearms and lower legs. An MRI was performed in 97.4%. Based on imaging, an IMM was suspected in 5.6% by radiologists and in 54.1% by musculoskeletal surgeons. An incision biopsy was performed in 68.4% and led in 100.0% to the right histopathological diagnosis. In total, 89.5% of IMMs were resected. Postoperative complications requiring revision occurred in 8.8%. Recurrences or degenerations of IMMs were not reported in any of these cases.

AB - Intramuscular myxomas (IMMs) are benign tumors. Evidence regarding diagnostic and therapeutic pathways is rare, and guidelines do not exist due to their low incidence. The aim of this study was a retrospective analysis at a university cancer center and the interdisciplinary re-evaluation of the individual diagnostic and therapeutic procedures. Overall, 38 patients were included in the study. IMMs occurred mostly in middle-aged women. At the time of first consultation, 57.9% had few symptoms or were asymptomatic. In 92.1% of the cases, the tumor was localized in the extremities. The lower extremity was affected in 73.7%. The average size of IMMs was 5.0 cm. The proximally located tumors in the gluteus, thighs, and upper arms were significantly larger (p = 0.02) than the distally-located tumors in the forearms and lower legs. An MRI was performed in 97.4%. Based on imaging, an IMM was suspected in 5.6% by radiologists and in 54.1% by musculoskeletal surgeons. An incision biopsy was performed in 68.4% and led in 100.0% to the right histopathological diagnosis. In total, 89.5% of IMMs were resected. Postoperative complications requiring revision occurred in 8.8%. Recurrences or degenerations of IMMs were not reported in any of these cases.

U2 - 10.3390/diagnostics12071573

DO - 10.3390/diagnostics12071573

M3 - SCORING: Journal article

VL - 12

JO - DIAGNOSTICS

JF - DIAGNOSTICS

SN - 2075-4418

IS - 7

M1 - 1573

ER -