Diagnostic and Therapeutic Pathways of Intramuscular Myxoma
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Diagnostic and Therapeutic Pathways of Intramuscular Myxoma. / Reiter, Alonja; Trumm, Katharina; Ballhause, Tobias Malte; Weiß, Sebastian; Frosch, Karl-Heinz; Korthaus, Alexander; Bechler, Ulrich; Duprée, Anna; Luebke, Andreas M.; Bannas, Peter; Schlickewei, Carsten; Priemel, Matthias.
in: DIAGNOSTICS, Jahrgang 12, Nr. 7, 1573, 28.06.2022.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Diagnostic and Therapeutic Pathways of Intramuscular Myxoma
AU - Reiter, Alonja
AU - Trumm, Katharina
AU - Ballhause, Tobias Malte
AU - Weiß, Sebastian
AU - Frosch, Karl-Heinz
AU - Korthaus, Alexander
AU - Bechler, Ulrich
AU - Duprée, Anna
AU - Luebke, Andreas M.
AU - Bannas, Peter
AU - Schlickewei, Carsten
AU - Priemel, Matthias
PY - 2022/6/28
Y1 - 2022/6/28
N2 - Intramuscular myxomas (IMMs) are benign tumors. Evidence regarding diagnostic and therapeutic pathways is rare, and guidelines do not exist due to their low incidence. The aim of this study was a retrospective analysis at a university cancer center and the interdisciplinary re-evaluation of the individual diagnostic and therapeutic procedures. Overall, 38 patients were included in the study. IMMs occurred mostly in middle-aged women. At the time of first consultation, 57.9% had few symptoms or were asymptomatic. In 92.1% of the cases, the tumor was localized in the extremities. The lower extremity was affected in 73.7%. The average size of IMMs was 5.0 cm. The proximally located tumors in the gluteus, thighs, and upper arms were significantly larger (p = 0.02) than the distally-located tumors in the forearms and lower legs. An MRI was performed in 97.4%. Based on imaging, an IMM was suspected in 5.6% by radiologists and in 54.1% by musculoskeletal surgeons. An incision biopsy was performed in 68.4% and led in 100.0% to the right histopathological diagnosis. In total, 89.5% of IMMs were resected. Postoperative complications requiring revision occurred in 8.8%. Recurrences or degenerations of IMMs were not reported in any of these cases.
AB - Intramuscular myxomas (IMMs) are benign tumors. Evidence regarding diagnostic and therapeutic pathways is rare, and guidelines do not exist due to their low incidence. The aim of this study was a retrospective analysis at a university cancer center and the interdisciplinary re-evaluation of the individual diagnostic and therapeutic procedures. Overall, 38 patients were included in the study. IMMs occurred mostly in middle-aged women. At the time of first consultation, 57.9% had few symptoms or were asymptomatic. In 92.1% of the cases, the tumor was localized in the extremities. The lower extremity was affected in 73.7%. The average size of IMMs was 5.0 cm. The proximally located tumors in the gluteus, thighs, and upper arms were significantly larger (p = 0.02) than the distally-located tumors in the forearms and lower legs. An MRI was performed in 97.4%. Based on imaging, an IMM was suspected in 5.6% by radiologists and in 54.1% by musculoskeletal surgeons. An incision biopsy was performed in 68.4% and led in 100.0% to the right histopathological diagnosis. In total, 89.5% of IMMs were resected. Postoperative complications requiring revision occurred in 8.8%. Recurrences or degenerations of IMMs were not reported in any of these cases.
U2 - 10.3390/diagnostics12071573
DO - 10.3390/diagnostics12071573
M3 - SCORING: Journal article
VL - 12
JO - DIAGNOSTICS
JF - DIAGNOSTICS
SN - 2075-4418
IS - 7
M1 - 1573
ER -