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Determination of 7-hydroxymethotrexate in human plasma by reversed phase high-performance liquid chromatography.

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Determination of 7-hydroxymethotrexate in human plasma by reversed phase high-performance liquid chromatography. / Erttmann, Rudolf; Bielack, S; Landbeck, G.

In: ONCOLOGY-BASEL, Vol. 43, No. 2, 2, 1986, p. 86-88.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Erttmann, R, Bielack, S & Landbeck, G 1986, 'Determination of 7-hydroxymethotrexate in human plasma by reversed phase high-performance liquid chromatography.', ONCOLOGY-BASEL, vol. 43, no. 2, 2, pp. 86-88. <http://www.ncbi.nlm.nih.gov/pubmed/3456549?dopt=Citation>

APA

Erttmann, R., Bielack, S., & Landbeck, G. (1986). Determination of 7-hydroxymethotrexate in human plasma by reversed phase high-performance liquid chromatography. ONCOLOGY-BASEL, 43(2), 86-88. [2]. http://www.ncbi.nlm.nih.gov/pubmed/3456549?dopt=Citation

Vancouver

Erttmann R, Bielack S, Landbeck G. Determination of 7-hydroxymethotrexate in human plasma by reversed phase high-performance liquid chromatography. ONCOLOGY-BASEL. 1986;43(2):86-88. 2.

Bibtex

@article{425caac718f043d191cf9644660f55b6,
title = "Determination of 7-hydroxymethotrexate in human plasma by reversed phase high-performance liquid chromatography.",
abstract = "A rapid and sensitive reversed phase HPLC method was developed for the detection of 7-hydroxymethotrexate (7-OHMTX) which is the main metabolite in human plasma after high-dose methotrexate (MTX) therapy. The simple clean-up procedure of plasma samples described allows the measurement of 7-OHMTX during clinical management of MTX infusions. Elimination kinetics of 7-OHMTX are given from 53 drug cycles of 6 patients.",
author = "Rudolf Erttmann and S Bielack and G Landbeck",
year = "1986",
language = "Deutsch",
volume = "43",
pages = "86--88",
journal = "ONCOLOGY-BASEL",
issn = "0030-2414",
publisher = "S. Karger AG",
number = "2",

}

RIS

TY - JOUR

T1 - Determination of 7-hydroxymethotrexate in human plasma by reversed phase high-performance liquid chromatography.

AU - Erttmann, Rudolf

AU - Bielack, S

AU - Landbeck, G

PY - 1986

Y1 - 1986

N2 - A rapid and sensitive reversed phase HPLC method was developed for the detection of 7-hydroxymethotrexate (7-OHMTX) which is the main metabolite in human plasma after high-dose methotrexate (MTX) therapy. The simple clean-up procedure of plasma samples described allows the measurement of 7-OHMTX during clinical management of MTX infusions. Elimination kinetics of 7-OHMTX are given from 53 drug cycles of 6 patients.

AB - A rapid and sensitive reversed phase HPLC method was developed for the detection of 7-hydroxymethotrexate (7-OHMTX) which is the main metabolite in human plasma after high-dose methotrexate (MTX) therapy. The simple clean-up procedure of plasma samples described allows the measurement of 7-OHMTX during clinical management of MTX infusions. Elimination kinetics of 7-OHMTX are given from 53 drug cycles of 6 patients.

M3 - SCORING: Zeitschriftenaufsatz

VL - 43

SP - 86

EP - 88

JO - ONCOLOGY-BASEL

JF - ONCOLOGY-BASEL

SN - 0030-2414

IS - 2

M1 - 2

ER -