Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

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Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany. / Schwarz, Tatjana; Tober-Lau, Pinkus; Hillus, David; Helbig, Elisa T; Lippert, Lena J; Thibeault, Charlotte; Koch, Willi; Landgraf, Irmgard; Michel, Janine; Bergfeld, Leon; Niemeyer, Daniela; Mühlemann, Barbara; Conrad, Claudia; Dang-Heine, Chantip; Kasper, Stefanie; Münn, Friederike; Kappert, Kai; Nitsche, Andreas; Tauber, Rudolf; Schmidt, Sein; Kopankiewicz, Piotr; Bias, Harald; Seybold, Joachim; von Kalle, Christof; Jones, Terry C; Suttorp, Norbert; Drosten, Christian; Sander, Leif Erik; Corman, Victor M; Kurth, Florian.

In: EMERG INFECT DIS, Vol. 27, No. 8, 08.2021, p. 2174-2178.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Schwarz, T, Tober-Lau, P, Hillus, D, Helbig, ET, Lippert, LJ, Thibeault, C, Koch, W, Landgraf, I, Michel, J, Bergfeld, L, Niemeyer, D, Mühlemann, B, Conrad, C, Dang-Heine, C, Kasper, S, Münn, F, Kappert, K, Nitsche, A, Tauber, R, Schmidt, S, Kopankiewicz, P, Bias, H, Seybold, J, von Kalle, C, Jones, TC, Suttorp, N, Drosten, C, Sander, LE, Corman, VM & Kurth, F 2021, 'Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany', EMERG INFECT DIS, vol. 27, no. 8, pp. 2174-2178. https://doi.org/10.3201/eid2708.211145

APA

Schwarz, T., Tober-Lau, P., Hillus, D., Helbig, E. T., Lippert, L. J., Thibeault, C., Koch, W., Landgraf, I., Michel, J., Bergfeld, L., Niemeyer, D., Mühlemann, B., Conrad, C., Dang-Heine, C., Kasper, S., Münn, F., Kappert, K., Nitsche, A., Tauber, R., ... Kurth, F. (2021). Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany. EMERG INFECT DIS, 27(8), 2174-2178. https://doi.org/10.3201/eid2708.211145

Vancouver

Schwarz T, Tober-Lau P, Hillus D, Helbig ET, Lippert LJ, Thibeault C et al. Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany. EMERG INFECT DIS. 2021 Aug;27(8):2174-2178. https://doi.org/10.3201/eid2708.211145

Bibtex

@article{8bdadcc923de42b384514eae030ba4a3,
title = "Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany",
abstract = "We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary.",
keywords = "Adult, Aged, Aged, 80 and over, BNT162 Vaccine, COVID-19, COVID-19 Vaccines, Germany/epidemiology, Humans, SARS-CoV-2, T-Lymphocytes, Vaccination",
author = "Tatjana Schwarz and Pinkus Tober-Lau and David Hillus and Helbig, {Elisa T} and Lippert, {Lena J} and Charlotte Thibeault and Willi Koch and Irmgard Landgraf and Janine Michel and Leon Bergfeld and Daniela Niemeyer and Barbara M{\"u}hlemann and Claudia Conrad and Chantip Dang-Heine and Stefanie Kasper and Friederike M{\"u}nn and Kai Kappert and Andreas Nitsche and Rudolf Tauber and Sein Schmidt and Piotr Kopankiewicz and Harald Bias and Joachim Seybold and {von Kalle}, Christof and Jones, {Terry C} and Norbert Suttorp and Christian Drosten and Sander, {Leif Erik} and Corman, {Victor M} and Florian Kurth",
year = "2021",
month = aug,
doi = "10.3201/eid2708.211145",
language = "English",
volume = "27",
pages = "2174--2178",
journal = "EMERG INFECT DIS",
issn = "1080-6040",
publisher = "Centers for Disease Control and Prevention (CDC)",
number = "8",

}

RIS

TY - JOUR

T1 - Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

AU - Schwarz, Tatjana

AU - Tober-Lau, Pinkus

AU - Hillus, David

AU - Helbig, Elisa T

AU - Lippert, Lena J

AU - Thibeault, Charlotte

AU - Koch, Willi

AU - Landgraf, Irmgard

AU - Michel, Janine

AU - Bergfeld, Leon

AU - Niemeyer, Daniela

AU - Mühlemann, Barbara

AU - Conrad, Claudia

AU - Dang-Heine, Chantip

AU - Kasper, Stefanie

AU - Münn, Friederike

AU - Kappert, Kai

AU - Nitsche, Andreas

AU - Tauber, Rudolf

AU - Schmidt, Sein

AU - Kopankiewicz, Piotr

AU - Bias, Harald

AU - Seybold, Joachim

AU - von Kalle, Christof

AU - Jones, Terry C

AU - Suttorp, Norbert

AU - Drosten, Christian

AU - Sander, Leif Erik

AU - Corman, Victor M

AU - Kurth, Florian

PY - 2021/8

Y1 - 2021/8

N2 - We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary.

AB - We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - BNT162 Vaccine

KW - COVID-19

KW - COVID-19 Vaccines

KW - Germany/epidemiology

KW - Humans

KW - SARS-CoV-2

KW - T-Lymphocytes

KW - Vaccination

U2 - 10.3201/eid2708.211145

DO - 10.3201/eid2708.211145

M3 - SCORING: Journal article

C2 - 34102097

VL - 27

SP - 2174

EP - 2178

JO - EMERG INFECT DIS

JF - EMERG INFECT DIS

SN - 1080-6040

IS - 8

ER -