Research ExplorerPublicationsDelayed Antibody and T-Cell Response to BNT162b2 Vaccination...

Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

  • Tatjana Schwarz (Shared first author)
  • Pinkus Tober-Lau (Shared first author)
  • David Hillus
  • Elisa T Helbig
  • Lena J Lippert
  • Charlotte Thibeault
  • Willi Koch
  • Irmgard Landgraf
  • Janine Michel
  • Leon Bergfeld
  • Daniela Niemeyer
  • Barbara Mühlemann
  • Claudia Conrad
  • Chantip Dang-Heine
  • Stefanie Kasper
  • Friederike Münn
  • Kai Kappert
  • Andreas Nitsche
  • Rudolf Tauber
  • Sein Schmidt
  • Piotr Kopankiewicz
  • Harald Bias
  • Joachim Seybold
  • Christof von Kalle
  • Terry C Jones
  • Norbert Suttorp
  • Christian Drosten
  • Leif Erik Sander (Shared last author)
  • Victor M Corman (Shared last author)
  • Florian Kurth (Shared last author)

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Abstract

We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary.

Bibliographical data

Original languageEnglish
ISSN1080-6040
DOIs
Publication statusPublished - 08.2021
PubMed 34102097