COVID-19 Vaccination and Uveitis: Epidemiology, Clinical Features and Visual Prognosis
Standard
COVID-19 Vaccination and Uveitis: Epidemiology, Clinical Features and Visual Prognosis. / Ferrand, Nawfel; Accorinti, Massimo; Agarwal, Mamta; Spartalis, Christoph; Manni, Priscilla; Stuebiger, Nicole; Zierhut, Manfred.
In: OCUL IMMUNOL INFLAMM, Vol. 30, No. 5, 07.2022, p. 1265-1273.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - COVID-19 Vaccination and Uveitis: Epidemiology, Clinical Features and Visual Prognosis
AU - Ferrand, Nawfel
AU - Accorinti, Massimo
AU - Agarwal, Mamta
AU - Spartalis, Christoph
AU - Manni, Priscilla
AU - Stuebiger, Nicole
AU - Zierhut, Manfred
PY - 2022/7
Y1 - 2022/7
N2 - PURPOSE: To study the epidemiological and clinical features of uveitis post-COVID-19 vaccination.PATIENTS AND METHODS: Retrospective chart review of patients presenting with uveitis after COVID-19 vaccination in tertiary uveitis services.RESULTS: In total, 25 patients, 76% females, mean age 43.2 years, were included. Uveitis occurred after Pfizer, Moderna, Astra-Zeneca and Covaxin vaccination. Anterior uveitis was the most frequent type of uveitis (56%). History of uveitis was found in 19 cases (76%), among whom 90.9% of the tested patients developed anti-Sars-CoV-2 spike antibodies after vaccination. In a mean follow-up of 5 months, one-line decrease in visual acuity was found in 12% of patients. During post-vaccine uveitis, 15.8% of cases needed an increase in their systemic therapy. According to Naranjo score, new-onset uveitis had a higher probability of being associated with vaccination (p < .01).CONCLUSION: COVID-19 vaccination can cause uveitis but has no significant impact on the visual prognosis after resolution.
AB - PURPOSE: To study the epidemiological and clinical features of uveitis post-COVID-19 vaccination.PATIENTS AND METHODS: Retrospective chart review of patients presenting with uveitis after COVID-19 vaccination in tertiary uveitis services.RESULTS: In total, 25 patients, 76% females, mean age 43.2 years, were included. Uveitis occurred after Pfizer, Moderna, Astra-Zeneca and Covaxin vaccination. Anterior uveitis was the most frequent type of uveitis (56%). History of uveitis was found in 19 cases (76%), among whom 90.9% of the tested patients developed anti-Sars-CoV-2 spike antibodies after vaccination. In a mean follow-up of 5 months, one-line decrease in visual acuity was found in 12% of patients. During post-vaccine uveitis, 15.8% of cases needed an increase in their systemic therapy. According to Naranjo score, new-onset uveitis had a higher probability of being associated with vaccination (p < .01).CONCLUSION: COVID-19 vaccination can cause uveitis but has no significant impact on the visual prognosis after resolution.
KW - Adult
KW - Female
KW - Humans
KW - Male
KW - Antibodies, Viral
KW - COVID-19/epidemiology
KW - COVID-19 Vaccines/adverse effects
KW - Follow-Up Studies
KW - Prognosis
KW - Retrospective Studies
KW - Uveitis/chemically induced
KW - Vaccination/adverse effects
U2 - 10.1080/09273948.2022.2058964
DO - 10.1080/09273948.2022.2058964
M3 - Other (editorial matter etc.)
C2 - 35404757
VL - 30
SP - 1265
EP - 1273
JO - OCUL IMMUNOL INFLAMM
JF - OCUL IMMUNOL INFLAMM
SN - 0927-3948
IS - 5
ER -