COVID-19 Vaccination and Uveitis: Epidemiology, Clinical Features and Visual Prognosis
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Abstract
PURPOSE: To study the epidemiological and clinical features of uveitis post-COVID-19 vaccination.
PATIENTS AND METHODS: Retrospective chart review of patients presenting with uveitis after COVID-19 vaccination in tertiary uveitis services.
RESULTS: In total, 25 patients, 76% females, mean age 43.2 years, were included. Uveitis occurred after Pfizer, Moderna, Astra-Zeneca and Covaxin vaccination. Anterior uveitis was the most frequent type of uveitis (56%). History of uveitis was found in 19 cases (76%), among whom 90.9% of the tested patients developed anti-Sars-CoV-2 spike antibodies after vaccination. In a mean follow-up of 5 months, one-line decrease in visual acuity was found in 12% of patients. During post-vaccine uveitis, 15.8% of cases needed an increase in their systemic therapy. According to Naranjo score, new-onset uveitis had a higher probability of being associated with vaccination (p < .01).
CONCLUSION: COVID-19 vaccination can cause uveitis but has no significant impact on the visual prognosis after resolution.
Bibliographical data
Original language | English |
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ISSN | 0927-3948 |
DOIs | |
Publication status | Published - 07.2022 |
PubMed | 35404757 |
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