Control of bleeding following functional endoscopic sinus surgery using carboxy-methylated cellulose packing

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Control of bleeding following functional endoscopic sinus surgery using carboxy-methylated cellulose packing. / Kastl, Konrad G; Betz, Christian S; Siedek, Vanessa; Leunig, Andreas.

In: EUR ARCH OTO-RHINO-L, Vol. 266, No. 8, 08.2009, p. 1239-43.

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@article{51ed4b5681544a5a818fab1b82768d6b,
title = "Control of bleeding following functional endoscopic sinus surgery using carboxy-methylated cellulose packing",
abstract = "The aim of this study is to evaluate the haemostatic effect of carboxy-methylated cellulose (CMC) nasal packing following functional endoscopic sinus surgery (FESS). The design includes an investigator-initiated, randomized, single-blinded, controlled, prospective clinical study. A bilateral FESS procedure was performed on 41 patients. At the end of the operation, one side was randomly filled with CMC nasal packing, the other side remained without packing. The patients were blinded to the side of nasal packing and were postoperatively examined on the 1st day, after 2 and 4 weeks and the extent of the postoperative bleeding was quantified with a clinical grading system. Even though there were slightly more postoperative bleedings reported for the non-packed sides as compared to the CMC-packed sides, these differences were at no point statistically significant within the monitored postoperative period of 4 weeks. In the examined collective, the CMC packing investigated did not statistically prove to have an effect on bleeding control in this study design.",
keywords = "Administration, Intranasal, Bandages, Biocompatible Materials, Carboxymethylcellulose Sodium, Chronic Disease, Endoscopy, Female, Follow-Up Studies, Humans, Male, Middle Aged, Nasal Polyps, Otorhinolaryngologic Surgical Procedures, Postoperative Hemorrhage, Prospective Studies, Rhinitis, Sinusitis, Comparative Study, Journal Article, Randomized Controlled Trial",
author = "Kastl, {Konrad G} and Betz, {Christian S} and Vanessa Siedek and Andreas Leunig",
year = "2009",
month = aug,
doi = "10.1007/s00405-008-0881-8",
language = "English",
volume = "266",
pages = "1239--43",
journal = "EUR ARCH OTO-RHINO-L",
issn = "0937-4477",
publisher = "Springer",
number = "8",

}

RIS

TY - JOUR

T1 - Control of bleeding following functional endoscopic sinus surgery using carboxy-methylated cellulose packing

AU - Kastl, Konrad G

AU - Betz, Christian S

AU - Siedek, Vanessa

AU - Leunig, Andreas

PY - 2009/8

Y1 - 2009/8

N2 - The aim of this study is to evaluate the haemostatic effect of carboxy-methylated cellulose (CMC) nasal packing following functional endoscopic sinus surgery (FESS). The design includes an investigator-initiated, randomized, single-blinded, controlled, prospective clinical study. A bilateral FESS procedure was performed on 41 patients. At the end of the operation, one side was randomly filled with CMC nasal packing, the other side remained without packing. The patients were blinded to the side of nasal packing and were postoperatively examined on the 1st day, after 2 and 4 weeks and the extent of the postoperative bleeding was quantified with a clinical grading system. Even though there were slightly more postoperative bleedings reported for the non-packed sides as compared to the CMC-packed sides, these differences were at no point statistically significant within the monitored postoperative period of 4 weeks. In the examined collective, the CMC packing investigated did not statistically prove to have an effect on bleeding control in this study design.

AB - The aim of this study is to evaluate the haemostatic effect of carboxy-methylated cellulose (CMC) nasal packing following functional endoscopic sinus surgery (FESS). The design includes an investigator-initiated, randomized, single-blinded, controlled, prospective clinical study. A bilateral FESS procedure was performed on 41 patients. At the end of the operation, one side was randomly filled with CMC nasal packing, the other side remained without packing. The patients were blinded to the side of nasal packing and were postoperatively examined on the 1st day, after 2 and 4 weeks and the extent of the postoperative bleeding was quantified with a clinical grading system. Even though there were slightly more postoperative bleedings reported for the non-packed sides as compared to the CMC-packed sides, these differences were at no point statistically significant within the monitored postoperative period of 4 weeks. In the examined collective, the CMC packing investigated did not statistically prove to have an effect on bleeding control in this study design.

KW - Administration, Intranasal

KW - Bandages

KW - Biocompatible Materials

KW - Carboxymethylcellulose Sodium

KW - Chronic Disease

KW - Endoscopy

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Nasal Polyps

KW - Otorhinolaryngologic Surgical Procedures

KW - Postoperative Hemorrhage

KW - Prospective Studies

KW - Rhinitis

KW - Sinusitis

KW - Comparative Study

KW - Journal Article

KW - Randomized Controlled Trial

U2 - 10.1007/s00405-008-0881-8

DO - 10.1007/s00405-008-0881-8

M3 - SCORING: Journal article

C2 - 19082836

VL - 266

SP - 1239

EP - 1243

JO - EUR ARCH OTO-RHINO-L

JF - EUR ARCH OTO-RHINO-L

SN - 0937-4477

IS - 8

ER -