Control of bleeding following functional endoscopic sinus surgery using carboxy-methylated cellulose packing
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Control of bleeding following functional endoscopic sinus surgery using carboxy-methylated cellulose packing. / Kastl, Konrad G; Betz, Christian S; Siedek, Vanessa; Leunig, Andreas.
in: EUR ARCH OTO-RHINO-L, Jahrgang 266, Nr. 8, 08.2009, S. 1239-43.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Control of bleeding following functional endoscopic sinus surgery using carboxy-methylated cellulose packing
AU - Kastl, Konrad G
AU - Betz, Christian S
AU - Siedek, Vanessa
AU - Leunig, Andreas
PY - 2009/8
Y1 - 2009/8
N2 - The aim of this study is to evaluate the haemostatic effect of carboxy-methylated cellulose (CMC) nasal packing following functional endoscopic sinus surgery (FESS). The design includes an investigator-initiated, randomized, single-blinded, controlled, prospective clinical study. A bilateral FESS procedure was performed on 41 patients. At the end of the operation, one side was randomly filled with CMC nasal packing, the other side remained without packing. The patients were blinded to the side of nasal packing and were postoperatively examined on the 1st day, after 2 and 4 weeks and the extent of the postoperative bleeding was quantified with a clinical grading system. Even though there were slightly more postoperative bleedings reported for the non-packed sides as compared to the CMC-packed sides, these differences were at no point statistically significant within the monitored postoperative period of 4 weeks. In the examined collective, the CMC packing investigated did not statistically prove to have an effect on bleeding control in this study design.
AB - The aim of this study is to evaluate the haemostatic effect of carboxy-methylated cellulose (CMC) nasal packing following functional endoscopic sinus surgery (FESS). The design includes an investigator-initiated, randomized, single-blinded, controlled, prospective clinical study. A bilateral FESS procedure was performed on 41 patients. At the end of the operation, one side was randomly filled with CMC nasal packing, the other side remained without packing. The patients were blinded to the side of nasal packing and were postoperatively examined on the 1st day, after 2 and 4 weeks and the extent of the postoperative bleeding was quantified with a clinical grading system. Even though there were slightly more postoperative bleedings reported for the non-packed sides as compared to the CMC-packed sides, these differences were at no point statistically significant within the monitored postoperative period of 4 weeks. In the examined collective, the CMC packing investigated did not statistically prove to have an effect on bleeding control in this study design.
KW - Administration, Intranasal
KW - Bandages
KW - Biocompatible Materials
KW - Carboxymethylcellulose Sodium
KW - Chronic Disease
KW - Endoscopy
KW - Female
KW - Follow-Up Studies
KW - Humans
KW - Male
KW - Middle Aged
KW - Nasal Polyps
KW - Otorhinolaryngologic Surgical Procedures
KW - Postoperative Hemorrhage
KW - Prospective Studies
KW - Rhinitis
KW - Sinusitis
KW - Comparative Study
KW - Journal Article
KW - Randomized Controlled Trial
U2 - 10.1007/s00405-008-0881-8
DO - 10.1007/s00405-008-0881-8
M3 - SCORING: Journal article
C2 - 19082836
VL - 266
SP - 1239
EP - 1243
JO - EUR ARCH OTO-RHINO-L
JF - EUR ARCH OTO-RHINO-L
SN - 0937-4477
IS - 8
ER -