Contemporary update of SPECT tracers and novelties in radioguided surgery: a perspective based on urology

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Contemporary update of SPECT tracers and novelties in radioguided surgery: a perspective based on urology. / Würnschimmel, Christoph; Wenzel, Mike; Maurer, Tobias; Valdés Olmos, Renato A; Vidal-Sicart, Sergi.

In: Q J NUCL MED MOL IM, Vol. 65, No. 3, 09.2021, p. 215-228.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{deb8fa85f2334986a0f42d891bd99969,
title = "Contemporary update of SPECT tracers and novelties in radioguided surgery: a perspective based on urology",
abstract = "Recent technical advances and implementation of novel radiotracers have further increased the potential of radioguided surgery for a broad variety of malignancies. Indeed, the possibilities for future applications of novel radiotracers in diverse oncological strategies has become more promising than ever. This literature review aims to provide a contemporary update on a selected group of radiotracers and evaluates the usability of radioguided surgery and sentinel node procedures, focusing on most promising advances. For example, the impact of targeted radiotracers on prostate specific membrane antigen (PSMA), CD206 receptor-targeted agents (99mTc-tilmanocept), and hybrid tracers adding fluorescence to radioguidance (ICG-99mTc-nanocolloid) as well as targeting hypoxia-induced carbonic anhydrase IX (CAIX) will be covered. Furthermore, future outlooks on the implementation of gold nanoparticles (AuNP's), but also technical advances in improved radiotracer detection by hybrid gamma devices will be discussed.",
keywords = "Gold, Humans, Indocyanine Green, Male, Metal Nanoparticles, Sentinel Lymph Node Biopsy, Surgery, Computer-Assisted, Tomography, Emission-Computed, Single-Photon, Urology",
author = "Christoph W{\"u}rnschimmel and Mike Wenzel and Tobias Maurer and {Vald{\'e}s Olmos}, {Renato A} and Sergi Vidal-Sicart",
year = "2021",
month = sep,
doi = "10.23736/S1824-4785.21.03345-8",
language = "English",
volume = "65",
pages = "215--228",
journal = "Q J NUCL MED MOL IM",
issn = "1824-4785",
publisher = "Edizioni Minerva Medica S.p.A.",
number = "3",

}

RIS

TY - JOUR

T1 - Contemporary update of SPECT tracers and novelties in radioguided surgery: a perspective based on urology

AU - Würnschimmel, Christoph

AU - Wenzel, Mike

AU - Maurer, Tobias

AU - Valdés Olmos, Renato A

AU - Vidal-Sicart, Sergi

PY - 2021/9

Y1 - 2021/9

N2 - Recent technical advances and implementation of novel radiotracers have further increased the potential of radioguided surgery for a broad variety of malignancies. Indeed, the possibilities for future applications of novel radiotracers in diverse oncological strategies has become more promising than ever. This literature review aims to provide a contemporary update on a selected group of radiotracers and evaluates the usability of radioguided surgery and sentinel node procedures, focusing on most promising advances. For example, the impact of targeted radiotracers on prostate specific membrane antigen (PSMA), CD206 receptor-targeted agents (99mTc-tilmanocept), and hybrid tracers adding fluorescence to radioguidance (ICG-99mTc-nanocolloid) as well as targeting hypoxia-induced carbonic anhydrase IX (CAIX) will be covered. Furthermore, future outlooks on the implementation of gold nanoparticles (AuNP's), but also technical advances in improved radiotracer detection by hybrid gamma devices will be discussed.

AB - Recent technical advances and implementation of novel radiotracers have further increased the potential of radioguided surgery for a broad variety of malignancies. Indeed, the possibilities for future applications of novel radiotracers in diverse oncological strategies has become more promising than ever. This literature review aims to provide a contemporary update on a selected group of radiotracers and evaluates the usability of radioguided surgery and sentinel node procedures, focusing on most promising advances. For example, the impact of targeted radiotracers on prostate specific membrane antigen (PSMA), CD206 receptor-targeted agents (99mTc-tilmanocept), and hybrid tracers adding fluorescence to radioguidance (ICG-99mTc-nanocolloid) as well as targeting hypoxia-induced carbonic anhydrase IX (CAIX) will be covered. Furthermore, future outlooks on the implementation of gold nanoparticles (AuNP's), but also technical advances in improved radiotracer detection by hybrid gamma devices will be discussed.

KW - Gold

KW - Humans

KW - Indocyanine Green

KW - Male

KW - Metal Nanoparticles

KW - Sentinel Lymph Node Biopsy

KW - Surgery, Computer-Assisted

KW - Tomography, Emission-Computed, Single-Photon

KW - Urology

U2 - 10.23736/S1824-4785.21.03345-8

DO - 10.23736/S1824-4785.21.03345-8

M3 - SCORING: Review article

C2 - 33829716

VL - 65

SP - 215

EP - 228

JO - Q J NUCL MED MOL IM

JF - Q J NUCL MED MOL IM

SN - 1824-4785

IS - 3

ER -