Combined T- and B-cell activation in childhood steroid-sensitive nephrotic syndrome.

  • Markus J. Kemper
  • T Meyer-Jark
  • M Lilova
  • D E Müller-Wiefel

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Abstract

Growing evidence shows that steroid-sensitive nephrotic syndrome (SSNS) is the result of a primary T-cell disturbance and leads to secondary anatomical and functional, however, not to immunological glomerular changes. In addition, immunoglobulin abnormalities in SSNS indicate a role of B-cell involvement.

Bibliographical data

Original languageEnglish
Article number4
ISSN0301-0430
Publication statusPublished - 2003
pubmed 14579938