Combined T- and B-cell activation in childhood steroid-sensitive nephrotic syndrome.

  • Markus J. Kemper
  • T Meyer-Jark
  • M Lilova
  • D E Müller-Wiefel

Abstract

Growing evidence shows that steroid-sensitive nephrotic syndrome (SSNS) is the result of a primary T-cell disturbance and leads to secondary anatomical and functional, however, not to immunological glomerular changes. In addition, immunoglobulin abnormalities in SSNS indicate a role of B-cell involvement.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer4
ISSN0301-0430
StatusVeröffentlicht - 2003
pubmed 14579938