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Characterisation of advanced glycation endproducts in saliva from patients with diabetes mellitus

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Characterisation of advanced glycation endproducts in saliva from patients with diabetes mellitus. / Yoon, Min-Sung; Jankowski, Vera; Montag, Susanne; Zidek, Walter; Henning, Lars; Schlüter, Hartmut; Tepel, Martin; Jankowski, Joachim.

In: BIOCHEM BIOPH RES CO, Vol. 323, No. 2, 15.10.2004, p. 377-81.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Yoon, M-S, Jankowski, V, Montag, S, Zidek, W, Henning, L, Schlüter, H, Tepel, M & Jankowski, J 2004, 'Characterisation of advanced glycation endproducts in saliva from patients with diabetes mellitus', BIOCHEM BIOPH RES CO, vol. 323, no. 2, pp. 377-81. https://doi.org/10.1016/j.bbrc.2004.08.118

APA

Yoon, M-S., Jankowski, V., Montag, S., Zidek, W., Henning, L., Schlüter, H., Tepel, M., & Jankowski, J. (2004). Characterisation of advanced glycation endproducts in saliva from patients with diabetes mellitus. BIOCHEM BIOPH RES CO, 323(2), 377-81. https://doi.org/10.1016/j.bbrc.2004.08.118

Vancouver

Yoon M-S, Jankowski V, Montag S, Zidek W, Henning L, Schlüter H et al. Characterisation of advanced glycation endproducts in saliva from patients with diabetes mellitus. BIOCHEM BIOPH RES CO. 2004 Oct 15;323(2):377-81. https://doi.org/10.1016/j.bbrc.2004.08.118

Bibtex

@article{e2dd93cb180a404eae1f73a1631b4add,
title = "Characterisation of advanced glycation endproducts in saliva from patients with diabetes mellitus",
abstract = "Patients with diabetes mellitus are prone to develop increased advanced glycation endproducts causing local complications and increased overall morbidity and mortality. Nuclear magnetic resonance spectra were determined in saliva of 52 consecutive patients with diabetes mellitus and 47 age-matched healthy control subjects. Resonance spectra showed specific peaks at 2.3, 7.3, and 8.4 ppm in saliva from patients with diabetes mellitus. These peaks could be generated by incubation of saliva from healthy control subjects with hypochloric acid in vitro, indicating the presence of advanced glycation endproducts. The presence of advanced glycation endproducts in patients with diabetes mellitus was associated with approximal plaque index, indicating increased periodontal damage. The study indicates that increased advanced glycation endproducts are involved in the pathogenesis of diabetic complications.",
keywords = "Adult, Biomarkers, Diabetes Complications, Diabetes Mellitus, Female, Glycation End Products, Advanced, Humans, Magnetic Resonance Spectroscopy, Male, Middle Aged, Periodontitis, Saliva, Clinical Trial, Controlled Clinical Trial, Journal Article",
author = "Min-Sung Yoon and Vera Jankowski and Susanne Montag and Walter Zidek and Lars Henning and Hartmut Schl{\"u}ter and Martin Tepel and Joachim Jankowski",
note = "Copyright 2004 Elsevier Inc.",
year = "2004",
month = oct,
day = "15",
doi = "10.1016/j.bbrc.2004.08.118",
language = "English",
volume = "323",
pages = "377--81",
journal = "BIOCHEM BIOPH RES CO",
issn = "0006-291X",
publisher = "Academic Press Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Characterisation of advanced glycation endproducts in saliva from patients with diabetes mellitus

AU - Yoon, Min-Sung

AU - Jankowski, Vera

AU - Montag, Susanne

AU - Zidek, Walter

AU - Henning, Lars

AU - Schlüter, Hartmut

AU - Tepel, Martin

AU - Jankowski, Joachim

N1 - Copyright 2004 Elsevier Inc.

PY - 2004/10/15

Y1 - 2004/10/15

N2 - Patients with diabetes mellitus are prone to develop increased advanced glycation endproducts causing local complications and increased overall morbidity and mortality. Nuclear magnetic resonance spectra were determined in saliva of 52 consecutive patients with diabetes mellitus and 47 age-matched healthy control subjects. Resonance spectra showed specific peaks at 2.3, 7.3, and 8.4 ppm in saliva from patients with diabetes mellitus. These peaks could be generated by incubation of saliva from healthy control subjects with hypochloric acid in vitro, indicating the presence of advanced glycation endproducts. The presence of advanced glycation endproducts in patients with diabetes mellitus was associated with approximal plaque index, indicating increased periodontal damage. The study indicates that increased advanced glycation endproducts are involved in the pathogenesis of diabetic complications.

AB - Patients with diabetes mellitus are prone to develop increased advanced glycation endproducts causing local complications and increased overall morbidity and mortality. Nuclear magnetic resonance spectra were determined in saliva of 52 consecutive patients with diabetes mellitus and 47 age-matched healthy control subjects. Resonance spectra showed specific peaks at 2.3, 7.3, and 8.4 ppm in saliva from patients with diabetes mellitus. These peaks could be generated by incubation of saliva from healthy control subjects with hypochloric acid in vitro, indicating the presence of advanced glycation endproducts. The presence of advanced glycation endproducts in patients with diabetes mellitus was associated with approximal plaque index, indicating increased periodontal damage. The study indicates that increased advanced glycation endproducts are involved in the pathogenesis of diabetic complications.

KW - Adult

KW - Biomarkers

KW - Diabetes Complications

KW - Diabetes Mellitus

KW - Female

KW - Glycation End Products, Advanced

KW - Humans

KW - Magnetic Resonance Spectroscopy

KW - Male

KW - Middle Aged

KW - Periodontitis

KW - Saliva

KW - Clinical Trial

KW - Controlled Clinical Trial

KW - Journal Article

U2 - 10.1016/j.bbrc.2004.08.118

DO - 10.1016/j.bbrc.2004.08.118

M3 - SCORING: Journal article

C2 - 15369762

VL - 323

SP - 377

EP - 381

JO - BIOCHEM BIOPH RES CO

JF - BIOCHEM BIOPH RES CO

SN - 0006-291X

IS - 2

ER -