Cerebral metastasis in recurrent squamous cell carcinoma of the vulva: case report and review of the literature

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@article{30c28ff1b2664e26a9ed978b29dbef48,
title = "Cerebral metastasis in recurrent squamous cell carcinoma of the vulva: case report and review of the literature",
abstract = "BACKGROUND: Distant metastases from squamous cell cancer of the vulva (VSCC) are encountered rarely and are associated with a poor prognosis. Cerebral metastases have only been described anecdotally.CASE HISTORY: A 51-year old woman was diagnosed with hepatic metastases due to VSCC. Initial therapy comprised wide local excision of the primary tumor with inguino-femoral lymphadenectomy (LAE) followed by stereotactic radiation of the singular hepatic metastasis while adjuvant chemoradiation of the vulva and lymphatics was declined. 3 years later, she subsequently developed lung and cerebral metastases.CONCLUSION: The course of metastatic disease in VSCC is poorly understood. Further knowledge of the metastatic patterns in vulvar cancer is required for guidance of future therapeutic interventions.",
author = "Anna Jaeger and Maxine Biermann and Katharina Prieske and Donata Grimm and Astrid Grottke and Johannes Salamon and Cordula Petersen and Volkmar Mueller and Barbara Schmalfeldt and Linn Woelber",
year = "2020",
month = feb,
doi = "10.1007/s00404-019-05403-6",
language = "English",
volume = "301",
pages = "327--332",
journal = "ARCH GYNECOL OBSTET",
issn = "0932-0067",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Cerebral metastasis in recurrent squamous cell carcinoma of the vulva: case report and review of the literature

AU - Jaeger, Anna

AU - Biermann, Maxine

AU - Prieske, Katharina

AU - Grimm, Donata

AU - Grottke, Astrid

AU - Salamon, Johannes

AU - Petersen, Cordula

AU - Mueller, Volkmar

AU - Schmalfeldt, Barbara

AU - Woelber, Linn

PY - 2020/2

Y1 - 2020/2

N2 - BACKGROUND: Distant metastases from squamous cell cancer of the vulva (VSCC) are encountered rarely and are associated with a poor prognosis. Cerebral metastases have only been described anecdotally.CASE HISTORY: A 51-year old woman was diagnosed with hepatic metastases due to VSCC. Initial therapy comprised wide local excision of the primary tumor with inguino-femoral lymphadenectomy (LAE) followed by stereotactic radiation of the singular hepatic metastasis while adjuvant chemoradiation of the vulva and lymphatics was declined. 3 years later, she subsequently developed lung and cerebral metastases.CONCLUSION: The course of metastatic disease in VSCC is poorly understood. Further knowledge of the metastatic patterns in vulvar cancer is required for guidance of future therapeutic interventions.

AB - BACKGROUND: Distant metastases from squamous cell cancer of the vulva (VSCC) are encountered rarely and are associated with a poor prognosis. Cerebral metastases have only been described anecdotally.CASE HISTORY: A 51-year old woman was diagnosed with hepatic metastases due to VSCC. Initial therapy comprised wide local excision of the primary tumor with inguino-femoral lymphadenectomy (LAE) followed by stereotactic radiation of the singular hepatic metastasis while adjuvant chemoradiation of the vulva and lymphatics was declined. 3 years later, she subsequently developed lung and cerebral metastases.CONCLUSION: The course of metastatic disease in VSCC is poorly understood. Further knowledge of the metastatic patterns in vulvar cancer is required for guidance of future therapeutic interventions.

U2 - 10.1007/s00404-019-05403-6

DO - 10.1007/s00404-019-05403-6

M3 - SCORING: Review article

C2 - 31823036

VL - 301

SP - 327

EP - 332

JO - ARCH GYNECOL OBSTET

JF - ARCH GYNECOL OBSTET

SN - 0932-0067

IS - 2

ER -