Cerebral metastasis in recurrent squamous cell carcinoma of the vulva: case report and review of the literature
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Cerebral metastasis in recurrent squamous cell carcinoma of the vulva: case report and review of the literature. / Jaeger, Anna; Biermann, Maxine; Prieske, Katharina; Grimm, Donata; Grottke, Astrid; Salamon, Johannes; Petersen, Cordula; Mueller, Volkmar; Schmalfeldt, Barbara; Woelber, Linn.
in: ARCH GYNECOL OBSTET, Jahrgang 301, Nr. 2, 02.2020, S. 327-332.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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T1 - Cerebral metastasis in recurrent squamous cell carcinoma of the vulva: case report and review of the literature
AU - Jaeger, Anna
AU - Biermann, Maxine
AU - Prieske, Katharina
AU - Grimm, Donata
AU - Grottke, Astrid
AU - Salamon, Johannes
AU - Petersen, Cordula
AU - Mueller, Volkmar
AU - Schmalfeldt, Barbara
AU - Woelber, Linn
PY - 2020/2
Y1 - 2020/2
N2 - BACKGROUND: Distant metastases from squamous cell cancer of the vulva (VSCC) are encountered rarely and are associated with a poor prognosis. Cerebral metastases have only been described anecdotally.CASE HISTORY: A 51-year old woman was diagnosed with hepatic metastases due to VSCC. Initial therapy comprised wide local excision of the primary tumor with inguino-femoral lymphadenectomy (LAE) followed by stereotactic radiation of the singular hepatic metastasis while adjuvant chemoradiation of the vulva and lymphatics was declined. 3 years later, she subsequently developed lung and cerebral metastases.CONCLUSION: The course of metastatic disease in VSCC is poorly understood. Further knowledge of the metastatic patterns in vulvar cancer is required for guidance of future therapeutic interventions.
AB - BACKGROUND: Distant metastases from squamous cell cancer of the vulva (VSCC) are encountered rarely and are associated with a poor prognosis. Cerebral metastases have only been described anecdotally.CASE HISTORY: A 51-year old woman was diagnosed with hepatic metastases due to VSCC. Initial therapy comprised wide local excision of the primary tumor with inguino-femoral lymphadenectomy (LAE) followed by stereotactic radiation of the singular hepatic metastasis while adjuvant chemoradiation of the vulva and lymphatics was declined. 3 years later, she subsequently developed lung and cerebral metastases.CONCLUSION: The course of metastatic disease in VSCC is poorly understood. Further knowledge of the metastatic patterns in vulvar cancer is required for guidance of future therapeutic interventions.
U2 - 10.1007/s00404-019-05403-6
DO - 10.1007/s00404-019-05403-6
M3 - SCORING: Review article
C2 - 31823036
VL - 301
SP - 327
EP - 332
JO - ARCH GYNECOL OBSTET
JF - ARCH GYNECOL OBSTET
SN - 0932-0067
IS - 2
ER -