Cerebellocerebral diaschisis is the likely mechanism of postsurgical posterior fossa syndrome in pediatric patients with midline cerebellar tumors.

Standard

Cerebellocerebral diaschisis is the likely mechanism of postsurgical posterior fossa syndrome in pediatric patients with midline cerebellar tumors. / Miller, N G; Reddick, W E; Kocak, M; Glass, J O; Löbel, Ulrike; Morris, B; Gajjar, A; Patay, Z.

In: AM J NEURORADIOL, Vol. 31, No. 2, 2, 2010, p. 288-294.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

APA

Vancouver

Bibtex

@article{39115b6e26524a68bf784b6dacca8048,
title = "Cerebellocerebral diaschisis is the likely mechanism of postsurgical posterior fossa syndrome in pediatric patients with midline cerebellar tumors.",
abstract = "PFS occurs in approximately 25% of pediatric patients receiving surgery for midline posterior fossa tumors. Increasing evidence suggests that PFS represents a complex supratentorial cortical dysfunction related to surgery-induced disruption of critical cerebellocerebral connections. The purpose of this study was to determine whether a consistent surgical damage pattern may be identified in patients with PFS by early postoperative anatomic imaging analysis of the pECP and to test whether DSC can detect corresponding changes in cerebral cortical perfusion to indicate a secondary, remote functional disturbance, which could suggest a diaschisis-like pathomechanism.",
keywords = "Humans, Male, Female, Child, Logistic Models, Child, Preschool, Retrospective Studies, Magnetic Resonance Imaging, Cerebellum pathology, Cerebral Cortex pathology, Syndrome, Cognition Disorders etiology, Cerebellar Neoplasms pathology, Cranial Fossa, Posterior pathology, Neural Pathways pathology, Postoperative Complications etiology, Humans, Male, Female, Child, Logistic Models, Child, Preschool, Retrospective Studies, Magnetic Resonance Imaging, Cerebellum pathology, Cerebral Cortex pathology, Syndrome, Cognition Disorders etiology, Cerebellar Neoplasms pathology, Cranial Fossa, Posterior pathology, Neural Pathways pathology, Postoperative Complications etiology",
author = "Miller, {N G} and Reddick, {W E} and M Kocak and Glass, {J O} and Ulrike L{\"o}bel and B Morris and A Gajjar and Z Patay",
year = "2010",
language = "Deutsch",
volume = "31",
pages = "288--294",
journal = "AM J NEURORADIOL",
issn = "0195-6108",
publisher = "American Society of Neuroradiology",
number = "2",

}

RIS

TY - JOUR

T1 - Cerebellocerebral diaschisis is the likely mechanism of postsurgical posterior fossa syndrome in pediatric patients with midline cerebellar tumors.

AU - Miller, N G

AU - Reddick, W E

AU - Kocak, M

AU - Glass, J O

AU - Löbel, Ulrike

AU - Morris, B

AU - Gajjar, A

AU - Patay, Z

PY - 2010

Y1 - 2010

N2 - PFS occurs in approximately 25% of pediatric patients receiving surgery for midline posterior fossa tumors. Increasing evidence suggests that PFS represents a complex supratentorial cortical dysfunction related to surgery-induced disruption of critical cerebellocerebral connections. The purpose of this study was to determine whether a consistent surgical damage pattern may be identified in patients with PFS by early postoperative anatomic imaging analysis of the pECP and to test whether DSC can detect corresponding changes in cerebral cortical perfusion to indicate a secondary, remote functional disturbance, which could suggest a diaschisis-like pathomechanism.

AB - PFS occurs in approximately 25% of pediatric patients receiving surgery for midline posterior fossa tumors. Increasing evidence suggests that PFS represents a complex supratentorial cortical dysfunction related to surgery-induced disruption of critical cerebellocerebral connections. The purpose of this study was to determine whether a consistent surgical damage pattern may be identified in patients with PFS by early postoperative anatomic imaging analysis of the pECP and to test whether DSC can detect corresponding changes in cerebral cortical perfusion to indicate a secondary, remote functional disturbance, which could suggest a diaschisis-like pathomechanism.

KW - Humans

KW - Male

KW - Female

KW - Child

KW - Logistic Models

KW - Child, Preschool

KW - Retrospective Studies

KW - Magnetic Resonance Imaging

KW - Cerebellum pathology

KW - Cerebral Cortex pathology

KW - Syndrome

KW - Cognition Disorders etiology

KW - Cerebellar Neoplasms pathology

KW - Cranial Fossa, Posterior pathology

KW - Neural Pathways pathology

KW - Postoperative Complications etiology

KW - Humans

KW - Male

KW - Female

KW - Child

KW - Logistic Models

KW - Child, Preschool

KW - Retrospective Studies

KW - Magnetic Resonance Imaging

KW - Cerebellum pathology

KW - Cerebral Cortex pathology

KW - Syndrome

KW - Cognition Disorders etiology

KW - Cerebellar Neoplasms pathology

KW - Cranial Fossa, Posterior pathology

KW - Neural Pathways pathology

KW - Postoperative Complications etiology

M3 - SCORING: Zeitschriftenaufsatz

VL - 31

SP - 288

EP - 294

JO - AM J NEURORADIOL

JF - AM J NEURORADIOL

SN - 0195-6108

IS - 2

M1 - 2

ER -