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Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex

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Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex. / Linke, Stephan J; Ceyrowski, Tim; Steinberg, Johannes; Kuhnhardt, Krister; Richard, Gisbert; Katz, Toam.

In: CORNEA, Vol. 32, No. 5, 01.05.2013, p. e127-35.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Linke, SJ, Ceyrowski, T, Steinberg, J, Kuhnhardt, K, Richard, G & Katz, T 2013, 'Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex', CORNEA, vol. 32, no. 5, pp. e127-35. https://doi.org/10.1097/ICO.0b013e3182772d29

APA

Linke, S. J., Ceyrowski, T., Steinberg, J., Kuhnhardt, K., Richard, G., & Katz, T. (2013). Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex. CORNEA, 32(5), e127-35. https://doi.org/10.1097/ICO.0b013e3182772d29

Vancouver

Linke SJ, Ceyrowski T, Steinberg J, Kuhnhardt K, Richard G, Katz T. Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex. CORNEA. 2013 May 1;32(5):e127-35. https://doi.org/10.1097/ICO.0b013e3182772d29

Bibtex

@article{5169141c55364c29ad4e1849b28615b4,
title = "Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex",
abstract = "PURPOSE: To quantify the difference in corneal thickness between the central and thinnest point (ΔCCT-TPCT) and the distance between the center of the cornea and its thinnest point (TPCT vector length) and to explore the impact of ocular side, refractive state, age, and sex.METHODS: Multicenter, retrospective, cross-sectional study. Medical records of 8054 eyes of 4027 refractive surgery candidates were reviewed. The correlation between ΔCCT-TPCT and TPCT vector length (Pentacam) and the variables refractive state, age, and sex were assessed. Spearman correlations, t tests, analysis of variance, analysis of covariance, and multiple regression models were used.RESULTS: ΔCCT-TPCT was higher in the left eyes of myopic (3.03 ± 2.29 µm) and hyperopic (4.97 ± 3.19 µm) subjects compared with myopic (2.39 ± 2.28 µm) and hyperopic (4.77 ± 3.97 µm; P < 0.05) right eyes. ΔCCT-TPCT was higher in hyperopic than in myopic (P < 0.001) eyes. TPCT vector length was 0.62 ± 0.28 mm for the right eye and 0.69 ± 0.24 mm for the left eye (P < 0.001). TPCT vector length tended to increase with advancing age. Age had the strongest independent effect on TPCT vector length in myopic (η = 0.018; P < 0.001) and hyperopic (η = 0.028; P = 0.006) right eyes. No difference was observed between male and female subjects. The correlations between ΔCCT-TPCT and TPCT vector length were strong (r > 0.8; P < 0.001).CONCLUSIONS: As a result of the significant differences found, normative data on ocular side, refractive state, and age should ideally be incorporated into ΔCCT-TPCT and TPCT vector length reference values.",
keywords = "Adult, Age Factors, Cornea, Corneal Pachymetry, Cross-Sectional Studies, Female, Humans, Hyperopia, Male, Middle Aged, Myopia, Refraction, Ocular, Retrospective Studies, Sex Factors, Visual Acuity",
author = "Linke, {Stephan J} and Tim Ceyrowski and Johannes Steinberg and Krister Kuhnhardt and Gisbert Richard and Toam Katz",
year = "2013",
month = may,
day = "1",
doi = "10.1097/ICO.0b013e3182772d29",
language = "English",
volume = "32",
pages = "e127--35",
journal = "CORNEA",
issn = "0277-3740",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

RIS

TY - JOUR

T1 - Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex

AU - Linke, Stephan J

AU - Ceyrowski, Tim

AU - Steinberg, Johannes

AU - Kuhnhardt, Krister

AU - Richard, Gisbert

AU - Katz, Toam

PY - 2013/5/1

Y1 - 2013/5/1

N2 - PURPOSE: To quantify the difference in corneal thickness between the central and thinnest point (ΔCCT-TPCT) and the distance between the center of the cornea and its thinnest point (TPCT vector length) and to explore the impact of ocular side, refractive state, age, and sex.METHODS: Multicenter, retrospective, cross-sectional study. Medical records of 8054 eyes of 4027 refractive surgery candidates were reviewed. The correlation between ΔCCT-TPCT and TPCT vector length (Pentacam) and the variables refractive state, age, and sex were assessed. Spearman correlations, t tests, analysis of variance, analysis of covariance, and multiple regression models were used.RESULTS: ΔCCT-TPCT was higher in the left eyes of myopic (3.03 ± 2.29 µm) and hyperopic (4.97 ± 3.19 µm) subjects compared with myopic (2.39 ± 2.28 µm) and hyperopic (4.77 ± 3.97 µm; P < 0.05) right eyes. ΔCCT-TPCT was higher in hyperopic than in myopic (P < 0.001) eyes. TPCT vector length was 0.62 ± 0.28 mm for the right eye and 0.69 ± 0.24 mm for the left eye (P < 0.001). TPCT vector length tended to increase with advancing age. Age had the strongest independent effect on TPCT vector length in myopic (η = 0.018; P < 0.001) and hyperopic (η = 0.028; P = 0.006) right eyes. No difference was observed between male and female subjects. The correlations between ΔCCT-TPCT and TPCT vector length were strong (r > 0.8; P < 0.001).CONCLUSIONS: As a result of the significant differences found, normative data on ocular side, refractive state, and age should ideally be incorporated into ΔCCT-TPCT and TPCT vector length reference values.

AB - PURPOSE: To quantify the difference in corneal thickness between the central and thinnest point (ΔCCT-TPCT) and the distance between the center of the cornea and its thinnest point (TPCT vector length) and to explore the impact of ocular side, refractive state, age, and sex.METHODS: Multicenter, retrospective, cross-sectional study. Medical records of 8054 eyes of 4027 refractive surgery candidates were reviewed. The correlation between ΔCCT-TPCT and TPCT vector length (Pentacam) and the variables refractive state, age, and sex were assessed. Spearman correlations, t tests, analysis of variance, analysis of covariance, and multiple regression models were used.RESULTS: ΔCCT-TPCT was higher in the left eyes of myopic (3.03 ± 2.29 µm) and hyperopic (4.97 ± 3.19 µm) subjects compared with myopic (2.39 ± 2.28 µm) and hyperopic (4.77 ± 3.97 µm; P < 0.05) right eyes. ΔCCT-TPCT was higher in hyperopic than in myopic (P < 0.001) eyes. TPCT vector length was 0.62 ± 0.28 mm for the right eye and 0.69 ± 0.24 mm for the left eye (P < 0.001). TPCT vector length tended to increase with advancing age. Age had the strongest independent effect on TPCT vector length in myopic (η = 0.018; P < 0.001) and hyperopic (η = 0.028; P = 0.006) right eyes. No difference was observed between male and female subjects. The correlations between ΔCCT-TPCT and TPCT vector length were strong (r > 0.8; P < 0.001).CONCLUSIONS: As a result of the significant differences found, normative data on ocular side, refractive state, and age should ideally be incorporated into ΔCCT-TPCT and TPCT vector length reference values.

KW - Adult

KW - Age Factors

KW - Cornea

KW - Corneal Pachymetry

KW - Cross-Sectional Studies

KW - Female

KW - Humans

KW - Hyperopia

KW - Male

KW - Middle Aged

KW - Myopia

KW - Refraction, Ocular

KW - Retrospective Studies

KW - Sex Factors

KW - Visual Acuity

U2 - 10.1097/ICO.0b013e3182772d29

DO - 10.1097/ICO.0b013e3182772d29

M3 - SCORING: Journal article

C2 - 23238394

VL - 32

SP - e127-35

JO - CORNEA

JF - CORNEA

SN - 0277-3740

IS - 5

ER -