Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex
Standard
Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex. / Linke, Stephan J; Ceyrowski, Tim; Steinberg, Johannes; Kuhnhardt, Krister; Richard, Gisbert; Katz, Toam.
in: CORNEA, Jahrgang 32, Nr. 5, 01.05.2013, S. e127-35.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex
AU - Linke, Stephan J
AU - Ceyrowski, Tim
AU - Steinberg, Johannes
AU - Kuhnhardt, Krister
AU - Richard, Gisbert
AU - Katz, Toam
PY - 2013/5/1
Y1 - 2013/5/1
N2 - PURPOSE: To quantify the difference in corneal thickness between the central and thinnest point (ΔCCT-TPCT) and the distance between the center of the cornea and its thinnest point (TPCT vector length) and to explore the impact of ocular side, refractive state, age, and sex.METHODS: Multicenter, retrospective, cross-sectional study. Medical records of 8054 eyes of 4027 refractive surgery candidates were reviewed. The correlation between ΔCCT-TPCT and TPCT vector length (Pentacam) and the variables refractive state, age, and sex were assessed. Spearman correlations, t tests, analysis of variance, analysis of covariance, and multiple regression models were used.RESULTS: ΔCCT-TPCT was higher in the left eyes of myopic (3.03 ± 2.29 µm) and hyperopic (4.97 ± 3.19 µm) subjects compared with myopic (2.39 ± 2.28 µm) and hyperopic (4.77 ± 3.97 µm; P < 0.05) right eyes. ΔCCT-TPCT was higher in hyperopic than in myopic (P < 0.001) eyes. TPCT vector length was 0.62 ± 0.28 mm for the right eye and 0.69 ± 0.24 mm for the left eye (P < 0.001). TPCT vector length tended to increase with advancing age. Age had the strongest independent effect on TPCT vector length in myopic (η = 0.018; P < 0.001) and hyperopic (η = 0.028; P = 0.006) right eyes. No difference was observed between male and female subjects. The correlations between ΔCCT-TPCT and TPCT vector length were strong (r > 0.8; P < 0.001).CONCLUSIONS: As a result of the significant differences found, normative data on ocular side, refractive state, and age should ideally be incorporated into ΔCCT-TPCT and TPCT vector length reference values.
AB - PURPOSE: To quantify the difference in corneal thickness between the central and thinnest point (ΔCCT-TPCT) and the distance between the center of the cornea and its thinnest point (TPCT vector length) and to explore the impact of ocular side, refractive state, age, and sex.METHODS: Multicenter, retrospective, cross-sectional study. Medical records of 8054 eyes of 4027 refractive surgery candidates were reviewed. The correlation between ΔCCT-TPCT and TPCT vector length (Pentacam) and the variables refractive state, age, and sex were assessed. Spearman correlations, t tests, analysis of variance, analysis of covariance, and multiple regression models were used.RESULTS: ΔCCT-TPCT was higher in the left eyes of myopic (3.03 ± 2.29 µm) and hyperopic (4.97 ± 3.19 µm) subjects compared with myopic (2.39 ± 2.28 µm) and hyperopic (4.77 ± 3.97 µm; P < 0.05) right eyes. ΔCCT-TPCT was higher in hyperopic than in myopic (P < 0.001) eyes. TPCT vector length was 0.62 ± 0.28 mm for the right eye and 0.69 ± 0.24 mm for the left eye (P < 0.001). TPCT vector length tended to increase with advancing age. Age had the strongest independent effect on TPCT vector length in myopic (η = 0.018; P < 0.001) and hyperopic (η = 0.028; P = 0.006) right eyes. No difference was observed between male and female subjects. The correlations between ΔCCT-TPCT and TPCT vector length were strong (r > 0.8; P < 0.001).CONCLUSIONS: As a result of the significant differences found, normative data on ocular side, refractive state, and age should ideally be incorporated into ΔCCT-TPCT and TPCT vector length reference values.
KW - Adult
KW - Age Factors
KW - Cornea
KW - Corneal Pachymetry
KW - Cross-Sectional Studies
KW - Female
KW - Humans
KW - Hyperopia
KW - Male
KW - Middle Aged
KW - Myopia
KW - Refraction, Ocular
KW - Retrospective Studies
KW - Sex Factors
KW - Visual Acuity
U2 - 10.1097/ICO.0b013e3182772d29
DO - 10.1097/ICO.0b013e3182772d29
M3 - SCORING: Journal article
C2 - 23238394
VL - 32
SP - e127-35
JO - CORNEA
JF - CORNEA
SN - 0277-3740
IS - 5
ER -