Cell cycle dependent G2 delay and killing of L929 cells after exposure to 241Am alpha particles.

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Cell cycle dependent G2 delay and killing of L929 cells after exposure to 241Am alpha particles. / Lücke-Huhle, C; Hieber, L; Beck-Bornholdt, Hans-Peter.

In: RADIAT RES, Vol. 100, No. 3, 3, 1984, p. 576-584.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Lücke-Huhle, C, Hieber, L & Beck-Bornholdt, H-P 1984, 'Cell cycle dependent G2 delay and killing of L929 cells after exposure to 241Am alpha particles.', RADIAT RES, vol. 100, no. 3, 3, pp. 576-584. <http://www.ncbi.nlm.nih.gov/pubmed/6505145?dopt=Citation>

APA

Vancouver

Lücke-Huhle C, Hieber L, Beck-Bornholdt H-P. Cell cycle dependent G2 delay and killing of L929 cells after exposure to 241Am alpha particles. RADIAT RES. 1984;100(3):576-584. 3.

Bibtex

@article{9507583709de4087a680505303aa848f,
title = "Cell cycle dependent G2 delay and killing of L929 cells after exposure to 241Am alpha particles.",
abstract = "Survival and G2 delay of L929 mouse fibroblasts exposed to 3.4-MeV alpha particles depend on the cell age at the time of irradiation. Greatest sensitivity for both endpoints has been found at the G1/S transition: The surviving fraction of G1/S cells is reduced to 0.11 following 1 Gy of alpha particles compared to 0.31 for early G1 cells. The G2 + M transit time rises from 3 hr for control cells to 22 and 30 hr for cells irradiated with 0.3 Gy in G2 or at the G1/S boundary, respectively. Cells irradiated in early G1 do not show increased G2 + M transit times. Growth delay as calculated for the entire population increases linearly with dose by 23 hr/Gy of alpha particles.",
author = "C L{\"u}cke-Huhle and L Hieber and Hans-Peter Beck-Bornholdt",
year = "1984",
language = "Deutsch",
volume = "100",
pages = "576--584",
number = "3",

}

RIS

TY - JOUR

T1 - Cell cycle dependent G2 delay and killing of L929 cells after exposure to 241Am alpha particles.

AU - Lücke-Huhle, C

AU - Hieber, L

AU - Beck-Bornholdt, Hans-Peter

PY - 1984

Y1 - 1984

N2 - Survival and G2 delay of L929 mouse fibroblasts exposed to 3.4-MeV alpha particles depend on the cell age at the time of irradiation. Greatest sensitivity for both endpoints has been found at the G1/S transition: The surviving fraction of G1/S cells is reduced to 0.11 following 1 Gy of alpha particles compared to 0.31 for early G1 cells. The G2 + M transit time rises from 3 hr for control cells to 22 and 30 hr for cells irradiated with 0.3 Gy in G2 or at the G1/S boundary, respectively. Cells irradiated in early G1 do not show increased G2 + M transit times. Growth delay as calculated for the entire population increases linearly with dose by 23 hr/Gy of alpha particles.

AB - Survival and G2 delay of L929 mouse fibroblasts exposed to 3.4-MeV alpha particles depend on the cell age at the time of irradiation. Greatest sensitivity for both endpoints has been found at the G1/S transition: The surviving fraction of G1/S cells is reduced to 0.11 following 1 Gy of alpha particles compared to 0.31 for early G1 cells. The G2 + M transit time rises from 3 hr for control cells to 22 and 30 hr for cells irradiated with 0.3 Gy in G2 or at the G1/S boundary, respectively. Cells irradiated in early G1 do not show increased G2 + M transit times. Growth delay as calculated for the entire population increases linearly with dose by 23 hr/Gy of alpha particles.

M3 - SCORING: Zeitschriftenaufsatz

VL - 100

SP - 576

EP - 584

IS - 3

M1 - 3

ER -