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CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia.

Standard

CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia. / Haferlach, Claudia; Bacher, Ulrike; Kohlmann, Alexander; Schindela, Sonja; Alpermann, Tamara; Kern, Wolfgang; Schnittger, Susanne; Haferlach, Torsten.

In: HAEMATOLOGICA, Vol. 96, No. 6, 6, 2011, p. 829-836.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Haferlach, C, Bacher, U, Kohlmann, A, Schindela, S, Alpermann, T, Kern, W, Schnittger, S & Haferlach, T 2011, 'CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia.', HAEMATOLOGICA, vol. 96, no. 6, 6, pp. 829-836. https://doi.org/10.3324/haematol.2010.035584

APA

Haferlach, C., Bacher, U., Kohlmann, A., Schindela, S., Alpermann, T., Kern, W., Schnittger, S., & Haferlach, T. (2011). CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia. HAEMATOLOGICA, 96(6), 829-836. [6]. https://doi.org/10.3324/haematol.2010.035584

Vancouver

Haferlach C, Bacher U, Kohlmann A, Schindela S, Alpermann T, Kern W et al. CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia. HAEMATOLOGICA. 2011;96(6):829-836. 6. https://doi.org/10.3324/haematol.2010.035584

Bibtex

@article{d7d82e30d4554778a0abd57b568d2e13,
title = "CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia.",
abstract = "Alterations of the short arm of chromosome 12 (12p) occur in various hematologic malignancies and ETV6 and CDKN1B, which are located on 12p, have been implicated as leukemogenic genes of interest.",
keywords = "Adult, Humans, Male, Aged, Female, Middle Aged, Aged, 80 and over, Prognosis, Survival Analysis, Chromosome Deletion, Gene Expression Profiling, Outcome Assessment (Health Care), In Situ Hybridization, Fluorescence, *Gene Expression Regulation, Neoplastic, Polymorphism, Single Nucleotide/genetics, RNA, Messenger/metabolism, Karyotyping, Chromosomes, Human, Pair 12/genetics, Cyclin-Dependent Kinase Inhibitor p27/*genetics, Leukemia, Myeloid, Acute/*diagnosis/genetics/mortality, Proto-Oncogene Proteins c-ets/genetics/metabolism, Repressor Proteins/genetics/metabolism, Tumor Markers, Biological/*genetics, Adult, Humans, Male, Aged, Female, Middle Aged, Aged, 80 and over, Prognosis, Survival Analysis, Chromosome Deletion, Gene Expression Profiling, Outcome Assessment (Health Care), In Situ Hybridization, Fluorescence, *Gene Expression Regulation, Neoplastic, Polymorphism, Single Nucleotide/genetics, RNA, Messenger/metabolism, Karyotyping, Chromosomes, Human, Pair 12/genetics, Cyclin-Dependent Kinase Inhibitor p27/*genetics, Leukemia, Myeloid, Acute/*diagnosis/genetics/mortality, Proto-Oncogene Proteins c-ets/genetics/metabolism, Repressor Proteins/genetics/metabolism, Tumor Markers, Biological/*genetics",
author = "Claudia Haferlach and Ulrike Bacher and Alexander Kohlmann and Sonja Schindela and Tamara Alpermann and Wolfgang Kern and Susanne Schnittger and Torsten Haferlach",
year = "2011",
doi = "10.3324/haematol.2010.035584",
language = "English",
volume = "96",
pages = "829--836",
journal = "HAEMATOLOGICA",
issn = "0390-6078",
publisher = "Ferrata Storti Foundation",
number = "6",

}

RIS

TY - JOUR

T1 - CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia.

AU - Haferlach, Claudia

AU - Bacher, Ulrike

AU - Kohlmann, Alexander

AU - Schindela, Sonja

AU - Alpermann, Tamara

AU - Kern, Wolfgang

AU - Schnittger, Susanne

AU - Haferlach, Torsten

PY - 2011

Y1 - 2011

N2 - Alterations of the short arm of chromosome 12 (12p) occur in various hematologic malignancies and ETV6 and CDKN1B, which are located on 12p, have been implicated as leukemogenic genes of interest.

AB - Alterations of the short arm of chromosome 12 (12p) occur in various hematologic malignancies and ETV6 and CDKN1B, which are located on 12p, have been implicated as leukemogenic genes of interest.

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Aged, 80 and over

KW - Prognosis

KW - Survival Analysis

KW - Chromosome Deletion

KW - Gene Expression Profiling

KW - Outcome Assessment (Health Care)

KW - In Situ Hybridization, Fluorescence

KW - Gene Expression Regulation, Neoplastic

KW - Polymorphism, Single Nucleotide/genetics

KW - RNA, Messenger/metabolism

KW - Karyotyping

KW - Chromosomes, Human, Pair 12/genetics

KW - Cyclin-Dependent Kinase Inhibitor p27/genetics

KW - Leukemia, Myeloid, Acute/diagnosis/genetics/mortality

KW - Proto-Oncogene Proteins c-ets/genetics/metabolism

KW - Repressor Proteins/genetics/metabolism

KW - Tumor Markers, Biological/genetics

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Aged, 80 and over

KW - Prognosis

KW - Survival Analysis

KW - Chromosome Deletion

KW - Gene Expression Profiling

KW - Outcome Assessment (Health Care)

KW - In Situ Hybridization, Fluorescence

KW - Gene Expression Regulation, Neoplastic

KW - Polymorphism, Single Nucleotide/genetics

KW - RNA, Messenger/metabolism

KW - Karyotyping

KW - Chromosomes, Human, Pair 12/genetics

KW - Cyclin-Dependent Kinase Inhibitor p27/genetics

KW - Leukemia, Myeloid, Acute/diagnosis/genetics/mortality

KW - Proto-Oncogene Proteins c-ets/genetics/metabolism

KW - Repressor Proteins/genetics/metabolism

KW - Tumor Markers, Biological/genetics

U2 - 10.3324/haematol.2010.035584

DO - 10.3324/haematol.2010.035584

M3 - SCORING: Journal article

VL - 96

SP - 829

EP - 836

JO - HAEMATOLOGICA

JF - HAEMATOLOGICA

SN - 0390-6078

IS - 6

M1 - 6

ER -