Candidate biomarkers in heart failure with reduced and preserved ejection fraction

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Candidate biomarkers in heart failure with reduced and preserved ejection fraction. / Sinning, Christoph; Zengin, Elvin; Zeller, Tanja; Schnabel, Renate B; Blankenberg, Stefan; Westermann, Dirk.

In: BIOMARKERS, Vol. 20, No. 4, 2015, p. 258-265.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{ed3b07f988e443318569255bf72667e8,
title = "Candidate biomarkers in heart failure with reduced and preserved ejection fraction",
abstract = "CONTEXT: Patients presenting with heart failure symptoms are categorized into heart failure (HF) with reduced and preserved ejection fraction.OBJECTIVE: Aim is to investigate the additional use of candidate biomarkers to characterize patients with either sub-type of HF.METHODS: Literature search was conducted in the electronic databases MEDLINE and Cochrane Central Register of Controlled Trials from inception through November 2014.RESULTS: The results of 47 diseased and general population cohorts were included.CONCLUSION: Current studies could outline the additional use of candidate biomarkers especially GDF-15, MR-proADM and high-sensitive determined troponin, although major outcome studies are still missing.",
keywords = "Adrenomedullin/analysis, Biomarkers/analysis, Growth Differentiation Factor 15/analysis, Heart Failure/diagnosis, Humans, Peptide Fragments/analysis, Prognosis, Protein Precursors/analysis, Sensitivity and Specificity, Stroke Volume",
author = "Christoph Sinning and Elvin Zengin and Tanja Zeller and Schnabel, {Renate B} and Stefan Blankenberg and Dirk Westermann",
year = "2015",
doi = "10.3109/1354750X.2015.1068856",
language = "English",
volume = "20",
pages = "258--265",
journal = "BIOMARKERS",
issn = "1354-750X",
publisher = "informa healthcare",
number = "4",

}

RIS

TY - JOUR

T1 - Candidate biomarkers in heart failure with reduced and preserved ejection fraction

AU - Sinning, Christoph

AU - Zengin, Elvin

AU - Zeller, Tanja

AU - Schnabel, Renate B

AU - Blankenberg, Stefan

AU - Westermann, Dirk

PY - 2015

Y1 - 2015

N2 - CONTEXT: Patients presenting with heart failure symptoms are categorized into heart failure (HF) with reduced and preserved ejection fraction.OBJECTIVE: Aim is to investigate the additional use of candidate biomarkers to characterize patients with either sub-type of HF.METHODS: Literature search was conducted in the electronic databases MEDLINE and Cochrane Central Register of Controlled Trials from inception through November 2014.RESULTS: The results of 47 diseased and general population cohorts were included.CONCLUSION: Current studies could outline the additional use of candidate biomarkers especially GDF-15, MR-proADM and high-sensitive determined troponin, although major outcome studies are still missing.

AB - CONTEXT: Patients presenting with heart failure symptoms are categorized into heart failure (HF) with reduced and preserved ejection fraction.OBJECTIVE: Aim is to investigate the additional use of candidate biomarkers to characterize patients with either sub-type of HF.METHODS: Literature search was conducted in the electronic databases MEDLINE and Cochrane Central Register of Controlled Trials from inception through November 2014.RESULTS: The results of 47 diseased and general population cohorts were included.CONCLUSION: Current studies could outline the additional use of candidate biomarkers especially GDF-15, MR-proADM and high-sensitive determined troponin, although major outcome studies are still missing.

KW - Adrenomedullin/analysis

KW - Biomarkers/analysis

KW - Growth Differentiation Factor 15/analysis

KW - Heart Failure/diagnosis

KW - Humans

KW - Peptide Fragments/analysis

KW - Prognosis

KW - Protein Precursors/analysis

KW - Sensitivity and Specificity

KW - Stroke Volume

U2 - 10.3109/1354750X.2015.1068856

DO - 10.3109/1354750X.2015.1068856

M3 - SCORING: Review article

C2 - 26301884

VL - 20

SP - 258

EP - 265

JO - BIOMARKERS

JF - BIOMARKERS

SN - 1354-750X

IS - 4

ER -