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Benign course of central pontine myelinolysis in a patient with anorexia nervosa

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Benign course of central pontine myelinolysis in a patient with anorexia nervosa. / Lilje, Christian G; Heinen, Florian; Laubenberger, Jörg; Krug, Isolde; Brandis, Matthias.

In: PEDIATR NEUROL, Vol. 27, No. 2, 08.2002, p. 132-5.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Lilje, CG, Heinen, F, Laubenberger, J, Krug, I & Brandis, M 2002, 'Benign course of central pontine myelinolysis in a patient with anorexia nervosa', PEDIATR NEUROL, vol. 27, no. 2, pp. 132-5. https://doi.org/10.1016/s0887-8994(02)00411-3

APA

Lilje, C. G., Heinen, F., Laubenberger, J., Krug, I., & Brandis, M. (2002). Benign course of central pontine myelinolysis in a patient with anorexia nervosa. PEDIATR NEUROL, 27(2), 132-5. https://doi.org/10.1016/s0887-8994(02)00411-3

Vancouver

Lilje CG, Heinen F, Laubenberger J, Krug I, Brandis M. Benign course of central pontine myelinolysis in a patient with anorexia nervosa. PEDIATR NEUROL. 2002 Aug;27(2):132-5. https://doi.org/10.1016/s0887-8994(02)00411-3

Bibtex

@article{1e7b611060e648b39a6ab6611de3b943,
title = "Benign course of central pontine myelinolysis in a patient with anorexia nervosa",
abstract = "Central pontine myelinolysis is a rare neurologic disorder defined by symmetric demyelination of the central base of the pons. Until recently its outcome was considered invariably poor if not fatal. We report a 15-year-old female patient with severe anorexia nervosa who acutely developed a locked-in syndrome. Magnetic resonance imaging revealed a central pontine lesion. There was no serum sodium abnormality. The corticospinal and corticonuclear tracts were intact, as assessed by serial neurophysiologic studies. Finally, the patient recovered completely both clinically and radiologically. This article discusses these observations in the light of recent reports on similar benign outcomes of central pontine myelinolysis. Although electrolyte imbalances could be overestimated and the clinical significance of the radiologic lesion is uncertain, the functional assessment of the corticospinal and corticonuclear fibers might have prognostic value.",
keywords = "Adolescent, Anorexia Nervosa/complications, Brain/pathology, Evoked Potentials, Auditory, Brain Stem/physiology, Evoked Potentials, Motor/physiology, Evoked Potentials, Visual/physiology, Female, Humans, Magnetic Resonance Imaging, Myelinolysis, Central Pontine/etiology, Severity of Illness Index, Water-Electrolyte Balance",
author = "Lilje, {Christian G} and Florian Heinen and J{\"o}rg Laubenberger and Isolde Krug and Matthias Brandis",
year = "2002",
month = aug,
doi = "10.1016/s0887-8994(02)00411-3",
language = "English",
volume = "27",
pages = "132--5",
journal = "PEDIATR NEUROL",
issn = "0887-8994",
publisher = "Elsevier Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Benign course of central pontine myelinolysis in a patient with anorexia nervosa

AU - Lilje, Christian G

AU - Heinen, Florian

AU - Laubenberger, Jörg

AU - Krug, Isolde

AU - Brandis, Matthias

PY - 2002/8

Y1 - 2002/8

N2 - Central pontine myelinolysis is a rare neurologic disorder defined by symmetric demyelination of the central base of the pons. Until recently its outcome was considered invariably poor if not fatal. We report a 15-year-old female patient with severe anorexia nervosa who acutely developed a locked-in syndrome. Magnetic resonance imaging revealed a central pontine lesion. There was no serum sodium abnormality. The corticospinal and corticonuclear tracts were intact, as assessed by serial neurophysiologic studies. Finally, the patient recovered completely both clinically and radiologically. This article discusses these observations in the light of recent reports on similar benign outcomes of central pontine myelinolysis. Although electrolyte imbalances could be overestimated and the clinical significance of the radiologic lesion is uncertain, the functional assessment of the corticospinal and corticonuclear fibers might have prognostic value.

AB - Central pontine myelinolysis is a rare neurologic disorder defined by symmetric demyelination of the central base of the pons. Until recently its outcome was considered invariably poor if not fatal. We report a 15-year-old female patient with severe anorexia nervosa who acutely developed a locked-in syndrome. Magnetic resonance imaging revealed a central pontine lesion. There was no serum sodium abnormality. The corticospinal and corticonuclear tracts were intact, as assessed by serial neurophysiologic studies. Finally, the patient recovered completely both clinically and radiologically. This article discusses these observations in the light of recent reports on similar benign outcomes of central pontine myelinolysis. Although electrolyte imbalances could be overestimated and the clinical significance of the radiologic lesion is uncertain, the functional assessment of the corticospinal and corticonuclear fibers might have prognostic value.

KW - Adolescent

KW - Anorexia Nervosa/complications

KW - Brain/pathology

KW - Evoked Potentials, Auditory, Brain Stem/physiology

KW - Evoked Potentials, Motor/physiology

KW - Evoked Potentials, Visual/physiology

KW - Female

KW - Humans

KW - Magnetic Resonance Imaging

KW - Myelinolysis, Central Pontine/etiology

KW - Severity of Illness Index

KW - Water-Electrolyte Balance

U2 - 10.1016/s0887-8994(02)00411-3

DO - 10.1016/s0887-8994(02)00411-3

M3 - SCORING: Journal article

C2 - 12213614

VL - 27

SP - 132

EP - 135

JO - PEDIATR NEUROL

JF - PEDIATR NEUROL

SN - 0887-8994

IS - 2

ER -