[Autoimmune liver diseases].

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[Autoimmune liver diseases]. / Pannicke, Nadine; Schramm, Christoph; Lohse, Ansgar W.

In: INTERNIST, Vol. 53, No. 8, 8, 2012, p. 943-946.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{e6b37e5ff3a04458bd754a475e54f36f,
title = "[Autoimmune liver diseases].",
abstract = "Autoimmune liver diseases are divided into autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). They play an important role in the differential diagnosis of acute and chronic liver diseases. Diagnostic criteria consist of biochemical parameters (liver function tests, immunoglobulins, autoantibodies), imaging (ultrasound, MRCP, ERCP) and histopathologic characteristics. The treatment of choice in AIH is a combined immunosuppressive therapy of prednisolone and azathioprine. Ursodeoxycholic acid is the treatment of choice for PBC and improves liver biochemistry and prolongs transplant-free survival by slowing histological progression in the majority of patients. To date, there is no effective medical treatment option for patients with PSC.",
keywords = "Diagnosis, Differential, Humans, Autoimmune Diseases/complications/*diagnosis/*therapy, Liver Diseases/complications/*diagnosis/*therapy, Diagnosis, Differential, Humans, Autoimmune Diseases/complications/*diagnosis/*therapy, Liver Diseases/complications/*diagnosis/*therapy",
author = "Nadine Pannicke and Christoph Schramm and Lohse, {Ansgar W.}",
year = "2012",
language = "Deutsch",
volume = "53",
pages = "943--946",
journal = "INTERNIST",
issn = "0020-9554",
publisher = "Springer",
number = "8",

}

RIS

TY - JOUR

T1 - [Autoimmune liver diseases].

AU - Pannicke, Nadine

AU - Schramm, Christoph

AU - Lohse, Ansgar W.

PY - 2012

Y1 - 2012

N2 - Autoimmune liver diseases are divided into autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). They play an important role in the differential diagnosis of acute and chronic liver diseases. Diagnostic criteria consist of biochemical parameters (liver function tests, immunoglobulins, autoantibodies), imaging (ultrasound, MRCP, ERCP) and histopathologic characteristics. The treatment of choice in AIH is a combined immunosuppressive therapy of prednisolone and azathioprine. Ursodeoxycholic acid is the treatment of choice for PBC and improves liver biochemistry and prolongs transplant-free survival by slowing histological progression in the majority of patients. To date, there is no effective medical treatment option for patients with PSC.

AB - Autoimmune liver diseases are divided into autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). They play an important role in the differential diagnosis of acute and chronic liver diseases. Diagnostic criteria consist of biochemical parameters (liver function tests, immunoglobulins, autoantibodies), imaging (ultrasound, MRCP, ERCP) and histopathologic characteristics. The treatment of choice in AIH is a combined immunosuppressive therapy of prednisolone and azathioprine. Ursodeoxycholic acid is the treatment of choice for PBC and improves liver biochemistry and prolongs transplant-free survival by slowing histological progression in the majority of patients. To date, there is no effective medical treatment option for patients with PSC.

KW - Diagnosis, Differential

KW - Humans

KW - Autoimmune Diseases/complications/diagnosis/therapy

KW - Liver Diseases/complications/diagnosis/therapy

KW - Diagnosis, Differential

KW - Humans

KW - Autoimmune Diseases/complications/diagnosis/therapy

KW - Liver Diseases/complications/diagnosis/therapy

M3 - SCORING: Zeitschriftenaufsatz

VL - 53

SP - 943

EP - 946

JO - INTERNIST

JF - INTERNIST

SN - 0020-9554

IS - 8

M1 - 8

ER -