Autoimmune Lebererkrankungen

Standard

Autoimmune Lebererkrankungen : Diagnostik und Therapie. / Bayer, E M; Schramm, C; Kanzler, S; Lohse, A W.

In: Z GASTROENTEROL, Vol. 42, No. 1, 01.2004, p. 19-30.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

Harvard

APA

Vancouver

Bibtex

@article{d3e87968742d4538b0c4a48b16121a62,
title = "Autoimmune Lebererkrankungen: Diagnostik und Therapie",
abstract = "Autoimmune Hepatitis (AIH), primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC) and overlap syndromes of these three disease entities are regarded as autoimmune liver diseases. These conditions are important differential diagnoses of elevated liver function tests as about 10 % of liver transplantations in Europe and North America are for these indications. The diagnosis is often difficult but can be facilitated by sequential measurement of relevant autoantibodies, exclusion of other liver disease, ultrasound, ERCP and liver histology. In AIH immunosuppressive therapy has been shown to prevent or stop the development of cirrhosis and improve the prognosis of the patients decisively. In other autoimmune liver diseases this evidence is missing making individual therapeutic decisions necessary. Ursodesoxycholic acid (UDCA) seems to slow disease progression in particular in early stages of PBC.",
keywords = "Adult, Autoantibodies, Autoimmune Diseases, Azathioprine, Biopsy, Child, Cholagogues and Choleretics, Cholangiopancreatography, Endoscopic Retrograde, Cholangitis, Sclerosing, Diagnosis, Differential, Enzyme-Linked Immunosorbent Assay, Female, Hepatitis, Autoimmune, Humans, Immunoassay, Immunosuppression, Immunosuppressive Agents, Liver, Liver Cirrhosis, Biliary, Liver Diseases, Liver Function Tests, Liver Transplantation, Male, Middle Aged, Mycophenolic Acid, Prognosis, Ultrasonography, Ursodeoxycholic Acid, Comparative Study, Journal Article, Review",
author = "Bayer, {E M} and C Schramm and S Kanzler and Lohse, {A W}",
year = "2004",
month = jan,
doi = "10.1055/s-2004-812686",
language = "Deutsch",
volume = "42",
pages = "19--30",
journal = "Z GASTROENTEROL",
issn = "0044-2771",
publisher = "Karl Demeter Verlag GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - Autoimmune Lebererkrankungen

T2 - Diagnostik und Therapie

AU - Bayer, E M

AU - Schramm, C

AU - Kanzler, S

AU - Lohse, A W

PY - 2004/1

Y1 - 2004/1

N2 - Autoimmune Hepatitis (AIH), primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC) and overlap syndromes of these three disease entities are regarded as autoimmune liver diseases. These conditions are important differential diagnoses of elevated liver function tests as about 10 % of liver transplantations in Europe and North America are for these indications. The diagnosis is often difficult but can be facilitated by sequential measurement of relevant autoantibodies, exclusion of other liver disease, ultrasound, ERCP and liver histology. In AIH immunosuppressive therapy has been shown to prevent or stop the development of cirrhosis and improve the prognosis of the patients decisively. In other autoimmune liver diseases this evidence is missing making individual therapeutic decisions necessary. Ursodesoxycholic acid (UDCA) seems to slow disease progression in particular in early stages of PBC.

AB - Autoimmune Hepatitis (AIH), primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC) and overlap syndromes of these three disease entities are regarded as autoimmune liver diseases. These conditions are important differential diagnoses of elevated liver function tests as about 10 % of liver transplantations in Europe and North America are for these indications. The diagnosis is often difficult but can be facilitated by sequential measurement of relevant autoantibodies, exclusion of other liver disease, ultrasound, ERCP and liver histology. In AIH immunosuppressive therapy has been shown to prevent or stop the development of cirrhosis and improve the prognosis of the patients decisively. In other autoimmune liver diseases this evidence is missing making individual therapeutic decisions necessary. Ursodesoxycholic acid (UDCA) seems to slow disease progression in particular in early stages of PBC.

KW - Adult

KW - Autoantibodies

KW - Autoimmune Diseases

KW - Azathioprine

KW - Biopsy

KW - Child

KW - Cholagogues and Choleretics

KW - Cholangiopancreatography, Endoscopic Retrograde

KW - Cholangitis, Sclerosing

KW - Diagnosis, Differential

KW - Enzyme-Linked Immunosorbent Assay

KW - Female

KW - Hepatitis, Autoimmune

KW - Humans

KW - Immunoassay

KW - Immunosuppression

KW - Immunosuppressive Agents

KW - Liver

KW - Liver Cirrhosis, Biliary

KW - Liver Diseases

KW - Liver Function Tests

KW - Liver Transplantation

KW - Male

KW - Middle Aged

KW - Mycophenolic Acid

KW - Prognosis

KW - Ultrasonography

KW - Ursodeoxycholic Acid

KW - Comparative Study

KW - Journal Article

KW - Review

U2 - 10.1055/s-2004-812686

DO - 10.1055/s-2004-812686

M3 - SCORING: Review

C2 - 14997400

VL - 42

SP - 19

EP - 30

JO - Z GASTROENTEROL

JF - Z GASTROENTEROL

SN - 0044-2771

IS - 1

ER -