Association of human papillomavirus infection with carcinoma of the cervix uteri and its precursor lesions: theoretical and practical implications.

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Association of human papillomavirus infection with carcinoma of the cervix uteri and its precursor lesions: theoretical and practical implications. / Milde-Langosch, K; Riethdorf, S; Löning, T.

In: VIRCHOWS ARCH, Vol. 437, No. 3, 3, 09.2000, p. 227-233.

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@article{3f410f2744f441eb89bd0d2aec3a88cc,
title = "Association of human papillomavirus infection with carcinoma of the cervix uteri and its precursor lesions: theoretical and practical implications.",
abstract = "Human papillomaviruses (HPVs) are the major aetiological agents of cervical carcinoma. In this review, epidemiological and molecular data are combined to present a model for HPV-induced cervical carcinogenesis. The impact of current knowledge regarding diagnostic and therapeutic approaches is shown, i.e. the use of HPV tests in cervical cancer screening, in the management of atypical smears of uncertain diagnosis and in smears indicative of mild dysplasias, as well as in follow-up examinations during and after therapy. In addition, the value of the two most frequently used HPV detection systems, polymerase-chain reaction (PCR) and hybrid capture (HC) analysis, is discussed.",
keywords = "Cervical Intraepithelial Neoplasia, Female, Humans, Papillomaviridae, Papillomavirus Infections, Precancerous Conditions, Tumor Virus Infections, Uterine Cervical Neoplasms",
author = "K Milde-Langosch and S Riethdorf and T L{\"o}ning",
year = "2000",
month = sep,
doi = "10.1007/s004280000234",
language = "English",
volume = "437",
pages = "227--233",
journal = "VIRCHOWS ARCH",
issn = "0945-6317",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - Association of human papillomavirus infection with carcinoma of the cervix uteri and its precursor lesions: theoretical and practical implications.

AU - Milde-Langosch, K

AU - Riethdorf, S

AU - Löning, T

PY - 2000/9

Y1 - 2000/9

N2 - Human papillomaviruses (HPVs) are the major aetiological agents of cervical carcinoma. In this review, epidemiological and molecular data are combined to present a model for HPV-induced cervical carcinogenesis. The impact of current knowledge regarding diagnostic and therapeutic approaches is shown, i.e. the use of HPV tests in cervical cancer screening, in the management of atypical smears of uncertain diagnosis and in smears indicative of mild dysplasias, as well as in follow-up examinations during and after therapy. In addition, the value of the two most frequently used HPV detection systems, polymerase-chain reaction (PCR) and hybrid capture (HC) analysis, is discussed.

AB - Human papillomaviruses (HPVs) are the major aetiological agents of cervical carcinoma. In this review, epidemiological and molecular data are combined to present a model for HPV-induced cervical carcinogenesis. The impact of current knowledge regarding diagnostic and therapeutic approaches is shown, i.e. the use of HPV tests in cervical cancer screening, in the management of atypical smears of uncertain diagnosis and in smears indicative of mild dysplasias, as well as in follow-up examinations during and after therapy. In addition, the value of the two most frequently used HPV detection systems, polymerase-chain reaction (PCR) and hybrid capture (HC) analysis, is discussed.

KW - Cervical Intraepithelial Neoplasia

KW - Female

KW - Humans

KW - Papillomaviridae

KW - Papillomavirus Infections

KW - Precancerous Conditions

KW - Tumor Virus Infections

KW - Uterine Cervical Neoplasms

U2 - 10.1007/s004280000234

DO - 10.1007/s004280000234

M3 - SCORING: Journal article

C2 - 11037341

VL - 437

SP - 227

EP - 233

JO - VIRCHOWS ARCH

JF - VIRCHOWS ARCH

SN - 0945-6317

IS - 3

M1 - 3

ER -