Association of human papillomavirus infection with carcinoma of the cervix uteri and its precursor lesions: theoretical and practical implications.
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Association of human papillomavirus infection with carcinoma of the cervix uteri and its precursor lesions: theoretical and practical implications. / Milde-Langosch, K; Riethdorf, S; Löning, T.
in: VIRCHOWS ARCH, Jahrgang 437, Nr. 3, 3, 09.2000, S. 227-233.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Association of human papillomavirus infection with carcinoma of the cervix uteri and its precursor lesions: theoretical and practical implications.
AU - Milde-Langosch, K
AU - Riethdorf, S
AU - Löning, T
PY - 2000/9
Y1 - 2000/9
N2 - Human papillomaviruses (HPVs) are the major aetiological agents of cervical carcinoma. In this review, epidemiological and molecular data are combined to present a model for HPV-induced cervical carcinogenesis. The impact of current knowledge regarding diagnostic and therapeutic approaches is shown, i.e. the use of HPV tests in cervical cancer screening, in the management of atypical smears of uncertain diagnosis and in smears indicative of mild dysplasias, as well as in follow-up examinations during and after therapy. In addition, the value of the two most frequently used HPV detection systems, polymerase-chain reaction (PCR) and hybrid capture (HC) analysis, is discussed.
AB - Human papillomaviruses (HPVs) are the major aetiological agents of cervical carcinoma. In this review, epidemiological and molecular data are combined to present a model for HPV-induced cervical carcinogenesis. The impact of current knowledge regarding diagnostic and therapeutic approaches is shown, i.e. the use of HPV tests in cervical cancer screening, in the management of atypical smears of uncertain diagnosis and in smears indicative of mild dysplasias, as well as in follow-up examinations during and after therapy. In addition, the value of the two most frequently used HPV detection systems, polymerase-chain reaction (PCR) and hybrid capture (HC) analysis, is discussed.
KW - Cervical Intraepithelial Neoplasia
KW - Female
KW - Humans
KW - Papillomaviridae
KW - Papillomavirus Infections
KW - Precancerous Conditions
KW - Tumor Virus Infections
KW - Uterine Cervical Neoplasms
U2 - 10.1007/s004280000234
DO - 10.1007/s004280000234
M3 - SCORING: Journal article
C2 - 11037341
VL - 437
SP - 227
EP - 233
JO - VIRCHOWS ARCH
JF - VIRCHOWS ARCH
SN - 0945-6317
IS - 3
M1 - 3
ER -