Association of Alcohol and Tobacco Consumption with Depression Severity in the Oldest Old. Results from the Age Different Old Age Cohort Platform
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Association of Alcohol and Tobacco Consumption with Depression Severity in the Oldest Old. Results from the Age Different Old Age Cohort Platform. / Quittschalle, Janine; Pabst, Alexander; Löbner, Margrit; Luppa, Melanie; Heser, Kathrin; Wagner, Michael E.; Bussche van den, Hendrik; Hajek, Andre; König, Hans-Helmut; Wiese, Birgitt; Angermeyer, Matthias; Maier, Wolfgang; Scherer, Martin; Riedel-Heller, Steffi G.
In: INT J ENV RES PUB HE, Vol. 18, No. 15, 28.07.2021, p. 7959.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Association of Alcohol and Tobacco Consumption with Depression Severity in the Oldest Old. Results from the Age Different Old Age Cohort Platform
AU - Quittschalle, Janine
AU - Pabst, Alexander
AU - Löbner, Margrit
AU - Luppa, Melanie
AU - Heser, Kathrin
AU - Wagner, Michael E.
AU - Bussche van den, Hendrik
AU - Hajek, Andre
AU - König, Hans-Helmut
AU - Wiese, Birgitt
AU - Angermeyer, Matthias
AU - Maier, Wolfgang
AU - Scherer, Martin
AU - Riedel-Heller, Steffi G
PY - 2021/7/28
Y1 - 2021/7/28
N2 - This study aimed to examine the association of alcohol and tobacco use with severity of depression in older age. Analyses were performed on a pooled data set (n = 3724) from two German old-age cohort studies (LEILA 75+, 6 follow-ups and AgeCoDe/AgeQualiDe, 9 follow-ups). Depressive symptoms were assessed via two screening scales for depression (CES-D and GDS-15) which were harmonized for pooled analysis. A mixed-effects linear regression model for the total sample and additional stratified models for men and women were used. Smoking at baseline was significantly associated with a higher level of depression severity (β = 0.142, 95% CI: 0.051-0.233, p = 0.002), whereas drinking was significantly associated with a decreased level of depression (β = -0.069, 95% CI: -0.119--0.021, p = 0.005). Concurrent substance use at baseline increased longitudinal depression severity (β = 0.193, 95% CI: 0.011-0.375, p = 0.037). Analyses stratified by gender showed a significant inverse association between drinking and depressive symptoms in men (β = -0.138, 95% CI: -0.231--0.045, p = 0.004), but not in women (β = -0.060, 95% CI: -0.120-0.001, p = 0.052). Given the burden of major depression, it is important that health care providers, especially primary care physicians, assess and monitor lifestyle factors, even at older ages.
AB - This study aimed to examine the association of alcohol and tobacco use with severity of depression in older age. Analyses were performed on a pooled data set (n = 3724) from two German old-age cohort studies (LEILA 75+, 6 follow-ups and AgeCoDe/AgeQualiDe, 9 follow-ups). Depressive symptoms were assessed via two screening scales for depression (CES-D and GDS-15) which were harmonized for pooled analysis. A mixed-effects linear regression model for the total sample and additional stratified models for men and women were used. Smoking at baseline was significantly associated with a higher level of depression severity (β = 0.142, 95% CI: 0.051-0.233, p = 0.002), whereas drinking was significantly associated with a decreased level of depression (β = -0.069, 95% CI: -0.119--0.021, p = 0.005). Concurrent substance use at baseline increased longitudinal depression severity (β = 0.193, 95% CI: 0.011-0.375, p = 0.037). Analyses stratified by gender showed a significant inverse association between drinking and depressive symptoms in men (β = -0.138, 95% CI: -0.231--0.045, p = 0.004), but not in women (β = -0.060, 95% CI: -0.120-0.001, p = 0.052). Given the burden of major depression, it is important that health care providers, especially primary care physicians, assess and monitor lifestyle factors, even at older ages.
U2 - 10.3390/ijerph18157959
DO - 10.3390/ijerph18157959
M3 - SCORING: Journal article
VL - 18
SP - 7959
JO - INT J ENV RES PUB HE
JF - INT J ENV RES PUB HE
SN - 1660-4601
IS - 15
ER -