Arp2/3:Not Absolutely Required After All?

Abstract

The Arp2/3 complex nucleates branched actin networks and is thought to be essential for macrophage migration and phagocytosis. In this issue of Developmental Cell, Rotty et al. (2017) show that there is only a surprisingly specific requirement for Arp2/3 in integrin-dependent macrophage functions, including CR3 phagocytosis and haptotaxis on fibronectin.

Bibliographical data

Original languageEnglish
ISSN1534-5807
DOIs
Publication statusPublished - 11.09.2017

Comment Deanary

Editorial Material

PubMed 28898673