Research ExplorerPublicationsAre cortical spreading depression and headache in migraine c...

Are cortical spreading depression and headache in migraine causally linked?

Standard

Are cortical spreading depression and headache in migraine causally linked? / Wolthausen, J; Sternberg, S; Gerloff, Christian; May, Arne.

In: CEPHALALGIA, Vol. 29, No. 2, 2, 2009, p. 244-249.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Wolthausen, J, Sternberg, S, Gerloff, C & May, A 2009, 'Are cortical spreading depression and headache in migraine causally linked?', CEPHALALGIA, vol. 29, no. 2, 2, pp. 244-249. <http://www.ncbi.nlm.nih.gov/pubmed/19025548?dopt=Citation>

APA

Wolthausen, J., Sternberg, S., Gerloff, C., & May, A. (2009). Are cortical spreading depression and headache in migraine causally linked? CEPHALALGIA, 29(2), 244-249. [2]. http://www.ncbi.nlm.nih.gov/pubmed/19025548?dopt=Citation

Vancouver

Wolthausen J, Sternberg S, Gerloff C, May A. Are cortical spreading depression and headache in migraine causally linked? CEPHALALGIA. 2009;29(2):244-249. 2.

Bibtex

@article{8c0001adff7a4dbdaf7f777de7d26c2a,
title = "Are cortical spreading depression and headache in migraine causally linked?",
abstract = "During the past few decades, much controversy has surrounded the pathophysiology of migraine. Cortical spreading depression (CSD) is widely accepted as the neuronal process underlying visual auras. It has been proposed that CSD can also cause the headaches, at least in migraine with aura. We describe three patients, each fulfilling the International Headache Society criteria for migraine with aura, who suffered from headaches 6-10 days per month. Two patients were treated with flunarizine and the third patient with topiramate for the duration of 4 months. All patients reported that aura symptoms resolved completely, whereas the migraine headache attacks persisted or even increased. These observations question the theory that CSD (silent or not) is a prerequisite for migraine headaches.",
author = "J Wolthausen and S Sternberg and Christian Gerloff and Arne May",
year = "2009",
language = "Deutsch",
volume = "29",
pages = "244--249",
journal = "CEPHALALGIA",
issn = "0333-1024",
publisher = "SAGE Publications",
number = "2",

}

RIS

TY - JOUR

T1 - Are cortical spreading depression and headache in migraine causally linked?

AU - Wolthausen, J

AU - Sternberg, S

AU - Gerloff, Christian

AU - May, Arne

PY - 2009

Y1 - 2009

N2 - During the past few decades, much controversy has surrounded the pathophysiology of migraine. Cortical spreading depression (CSD) is widely accepted as the neuronal process underlying visual auras. It has been proposed that CSD can also cause the headaches, at least in migraine with aura. We describe three patients, each fulfilling the International Headache Society criteria for migraine with aura, who suffered from headaches 6-10 days per month. Two patients were treated with flunarizine and the third patient with topiramate for the duration of 4 months. All patients reported that aura symptoms resolved completely, whereas the migraine headache attacks persisted or even increased. These observations question the theory that CSD (silent or not) is a prerequisite for migraine headaches.

AB - During the past few decades, much controversy has surrounded the pathophysiology of migraine. Cortical spreading depression (CSD) is widely accepted as the neuronal process underlying visual auras. It has been proposed that CSD can also cause the headaches, at least in migraine with aura. We describe three patients, each fulfilling the International Headache Society criteria for migraine with aura, who suffered from headaches 6-10 days per month. Two patients were treated with flunarizine and the third patient with topiramate for the duration of 4 months. All patients reported that aura symptoms resolved completely, whereas the migraine headache attacks persisted or even increased. These observations question the theory that CSD (silent or not) is a prerequisite for migraine headaches.

M3 - SCORING: Zeitschriftenaufsatz

VL - 29

SP - 244

EP - 249

JO - CEPHALALGIA

JF - CEPHALALGIA

SN - 0333-1024

IS - 2

M1 - 2

ER -