Apoptosis-related deregulation of proteolytic activities and high serum levels of circulating nucleosomes and DNA in blood correlate with breast cancer progression.
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Apoptosis-related deregulation of proteolytic activities and high serum levels of circulating nucleosomes and DNA in blood correlate with breast cancer progression. / Roth, Carina; Pantel, Klaus; Müller, Volkmar; Rack, Brigitte; Kasimir-Bauer, Sabine; Janni, Wolfgang; Schwarzenbach, Heidi.
In: BMC CANCER, Vol. 11, 2011, p. 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Apoptosis-related deregulation of proteolytic activities and high serum levels of circulating nucleosomes and DNA in blood correlate with breast cancer progression.
AU - Roth, Carina
AU - Pantel, Klaus
AU - Müller, Volkmar
AU - Rack, Brigitte
AU - Kasimir-Bauer, Sabine
AU - Janni, Wolfgang
AU - Schwarzenbach, Heidi
PY - 2011
Y1 - 2011
N2 - As cell-free circulating DNA exists predominantly as mono- and oligonucleosomes, the focus of the current study was to examine the interplay of circulating nucleosomes, DNA, proteases and caspases in blood of patients with benign and malignant breast diseases.
AB - As cell-free circulating DNA exists predominantly as mono- and oligonucleosomes, the focus of the current study was to examine the interplay of circulating nucleosomes, DNA, proteases and caspases in blood of patients with benign and malignant breast diseases.
KW - Adult
KW - Humans
KW - Aged
KW - Female
KW - Middle Aged
KW - Aged, 80 and over
KW - Adolescent
KW - Young Adult
KW - Disease Progression
KW - Enzyme-Linked Immunosorbent Assay
KW - DNA, Neoplasm/blood
KW - Apoptosis
KW - Breast Neoplasms/blood/pathology
KW - Caspase 3/blood/metabolism
KW - Caspase 7/blood/metabolism
KW - Nucleosomes/metabolism
KW - Peptide Hydrolases/blood/metabolism
KW - Adult
KW - Humans
KW - Aged
KW - Female
KW - Middle Aged
KW - Aged, 80 and over
KW - Adolescent
KW - Young Adult
KW - Disease Progression
KW - Enzyme-Linked Immunosorbent Assay
KW - DNA, Neoplasm/blood
KW - Apoptosis
KW - Breast Neoplasms/blood/pathology
KW - Caspase 3/blood/metabolism
KW - Caspase 7/blood/metabolism
KW - Nucleosomes/metabolism
KW - Peptide Hydrolases/blood/metabolism
U2 - 10.1186/1471-2407-11-4
DO - 10.1186/1471-2407-11-4
M3 - SCORING: Journal article
VL - 11
SP - 4
JO - BMC CANCER
JF - BMC CANCER
SN - 1471-2407
ER -