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Anesthesia with Propofol versus Sevoflurane

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Anesthesia with Propofol versus Sevoflurane : Does the Longer Neuromuscular Block under Sevoflurane Anesthesia Reduce Laryngeal Injuries? / Mencke, Thomas; Zitzmann, Amelie; Machmueller, Susann; Boettcher, Arne; Sauer, Martin; Pau, Hans Wilhelm; Noeldge-Schomburg, Gabriele; Dommerich, Steffen.

In: ANESTHESIOL RES PRAC, Vol. 2013, 2013, p. 723168.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Mencke, T, Zitzmann, A, Machmueller, S, Boettcher, A, Sauer, M, Pau, HW, Noeldge-Schomburg, G & Dommerich, S 2013, 'Anesthesia with Propofol versus Sevoflurane: Does the Longer Neuromuscular Block under Sevoflurane Anesthesia Reduce Laryngeal Injuries?', ANESTHESIOL RES PRAC, vol. 2013, pp. 723168. https://doi.org/10.1155/2013/723168

APA

Mencke, T., Zitzmann, A., Machmueller, S., Boettcher, A., Sauer, M., Pau, H. W., Noeldge-Schomburg, G., & Dommerich, S. (2013). Anesthesia with Propofol versus Sevoflurane: Does the Longer Neuromuscular Block under Sevoflurane Anesthesia Reduce Laryngeal Injuries? ANESTHESIOL RES PRAC, 2013, 723168. https://doi.org/10.1155/2013/723168

Vancouver

Mencke T, Zitzmann A, Machmueller S, Boettcher A, Sauer M, Pau HW et al. Anesthesia with Propofol versus Sevoflurane: Does the Longer Neuromuscular Block under Sevoflurane Anesthesia Reduce Laryngeal Injuries? ANESTHESIOL RES PRAC. 2013;2013:723168. https://doi.org/10.1155/2013/723168

Bibtex

@article{4236104b3b8e418f8d596aeb7e3627db,
title = "Anesthesia with Propofol versus Sevoflurane: Does the Longer Neuromuscular Block under Sevoflurane Anesthesia Reduce Laryngeal Injuries?",
abstract = "Anesthesia can be maintained with propofol or sevoflurane. Volatile anesthetics increase neuromuscular block of muscle relaxants. We tested the hypothesis, that sevoflurane would cause less vocal cord injuries than an intravenous anesthesia with propofol. In this prospective trial, 65 patients were randomized in 2 groups: SEVO group, anesthesia with sevoflurane, and TIVA group, total intravenous anesthesia with propofol. Intubating and extubating conditions were evaluated. Vocal cord injuries were examined by stroboscopy before and 24 and 72 h after surgery; hoarseness and sore throat were assessed up to 72 h after surgery. Hoarseness and sore throat were comparable between both groups (not significant). Similar findings were observed for vocal cord injuries: 9 (SEVO) versus 5 (TIVA) patients; P = 0.36; the overall incidence was 24%. Type of vocal cord injuries: 9 erythema and 5 edema of the vocal folds. Neuromuscular block was significantly longer in the SEVO group compared with the TIVA group: 71 (range: 38-148) min versus 52 (range: 21-74) min; P < 0.001. Five patients (TIVA group) versus 11 patients (SEVO group) needed neostigmine to achieve a TOF ratio of 1.0 (P = 0.14). Under anesthesia with propofol laryngeal injuries were not increased; the risk for residual curarization, however, was lower compared with sevoflurane.",
keywords = "Journal Article",
author = "Thomas Mencke and Amelie Zitzmann and Susann Machmueller and Arne Boettcher and Martin Sauer and Pau, {Hans Wilhelm} and Gabriele Noeldge-Schomburg and Steffen Dommerich",
year = "2013",
doi = "10.1155/2013/723168",
language = "English",
volume = "2013",
pages = "723168",
journal = "ANESTHESIOL RES PRAC",
issn = "1687-6962",
publisher = "Hindawi Publishing Corporation",

}

RIS

TY - JOUR

T1 - Anesthesia with Propofol versus Sevoflurane

T2 - Does the Longer Neuromuscular Block under Sevoflurane Anesthesia Reduce Laryngeal Injuries?

AU - Mencke, Thomas

AU - Zitzmann, Amelie

AU - Machmueller, Susann

AU - Boettcher, Arne

AU - Sauer, Martin

AU - Pau, Hans Wilhelm

AU - Noeldge-Schomburg, Gabriele

AU - Dommerich, Steffen

PY - 2013

Y1 - 2013

N2 - Anesthesia can be maintained with propofol or sevoflurane. Volatile anesthetics increase neuromuscular block of muscle relaxants. We tested the hypothesis, that sevoflurane would cause less vocal cord injuries than an intravenous anesthesia with propofol. In this prospective trial, 65 patients were randomized in 2 groups: SEVO group, anesthesia with sevoflurane, and TIVA group, total intravenous anesthesia with propofol. Intubating and extubating conditions were evaluated. Vocal cord injuries were examined by stroboscopy before and 24 and 72 h after surgery; hoarseness and sore throat were assessed up to 72 h after surgery. Hoarseness and sore throat were comparable between both groups (not significant). Similar findings were observed for vocal cord injuries: 9 (SEVO) versus 5 (TIVA) patients; P = 0.36; the overall incidence was 24%. Type of vocal cord injuries: 9 erythema and 5 edema of the vocal folds. Neuromuscular block was significantly longer in the SEVO group compared with the TIVA group: 71 (range: 38-148) min versus 52 (range: 21-74) min; P < 0.001. Five patients (TIVA group) versus 11 patients (SEVO group) needed neostigmine to achieve a TOF ratio of 1.0 (P = 0.14). Under anesthesia with propofol laryngeal injuries were not increased; the risk for residual curarization, however, was lower compared with sevoflurane.

AB - Anesthesia can be maintained with propofol or sevoflurane. Volatile anesthetics increase neuromuscular block of muscle relaxants. We tested the hypothesis, that sevoflurane would cause less vocal cord injuries than an intravenous anesthesia with propofol. In this prospective trial, 65 patients were randomized in 2 groups: SEVO group, anesthesia with sevoflurane, and TIVA group, total intravenous anesthesia with propofol. Intubating and extubating conditions were evaluated. Vocal cord injuries were examined by stroboscopy before and 24 and 72 h after surgery; hoarseness and sore throat were assessed up to 72 h after surgery. Hoarseness and sore throat were comparable between both groups (not significant). Similar findings were observed for vocal cord injuries: 9 (SEVO) versus 5 (TIVA) patients; P = 0.36; the overall incidence was 24%. Type of vocal cord injuries: 9 erythema and 5 edema of the vocal folds. Neuromuscular block was significantly longer in the SEVO group compared with the TIVA group: 71 (range: 38-148) min versus 52 (range: 21-74) min; P < 0.001. Five patients (TIVA group) versus 11 patients (SEVO group) needed neostigmine to achieve a TOF ratio of 1.0 (P = 0.14). Under anesthesia with propofol laryngeal injuries were not increased; the risk for residual curarization, however, was lower compared with sevoflurane.

KW - Journal Article

U2 - 10.1155/2013/723168

DO - 10.1155/2013/723168

M3 - SCORING: Journal article

C2 - 23533393

VL - 2013

SP - 723168

JO - ANESTHESIOL RES PRAC

JF - ANESTHESIOL RES PRAC

SN - 1687-6962

ER -