Anesthesia with Propofol versus Sevoflurane
Standard
Anesthesia with Propofol versus Sevoflurane : Does the Longer Neuromuscular Block under Sevoflurane Anesthesia Reduce Laryngeal Injuries? / Mencke, Thomas; Zitzmann, Amelie; Machmueller, Susann; Boettcher, Arne; Sauer, Martin; Pau, Hans Wilhelm; Noeldge-Schomburg, Gabriele; Dommerich, Steffen.
in: ANESTHESIOL RES PRAC, Jahrgang 2013, 2013, S. 723168.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Anesthesia with Propofol versus Sevoflurane
T2 - Does the Longer Neuromuscular Block under Sevoflurane Anesthesia Reduce Laryngeal Injuries?
AU - Mencke, Thomas
AU - Zitzmann, Amelie
AU - Machmueller, Susann
AU - Boettcher, Arne
AU - Sauer, Martin
AU - Pau, Hans Wilhelm
AU - Noeldge-Schomburg, Gabriele
AU - Dommerich, Steffen
PY - 2013
Y1 - 2013
N2 - Anesthesia can be maintained with propofol or sevoflurane. Volatile anesthetics increase neuromuscular block of muscle relaxants. We tested the hypothesis, that sevoflurane would cause less vocal cord injuries than an intravenous anesthesia with propofol. In this prospective trial, 65 patients were randomized in 2 groups: SEVO group, anesthesia with sevoflurane, and TIVA group, total intravenous anesthesia with propofol. Intubating and extubating conditions were evaluated. Vocal cord injuries were examined by stroboscopy before and 24 and 72 h after surgery; hoarseness and sore throat were assessed up to 72 h after surgery. Hoarseness and sore throat were comparable between both groups (not significant). Similar findings were observed for vocal cord injuries: 9 (SEVO) versus 5 (TIVA) patients; P = 0.36; the overall incidence was 24%. Type of vocal cord injuries: 9 erythema and 5 edema of the vocal folds. Neuromuscular block was significantly longer in the SEVO group compared with the TIVA group: 71 (range: 38-148) min versus 52 (range: 21-74) min; P < 0.001. Five patients (TIVA group) versus 11 patients (SEVO group) needed neostigmine to achieve a TOF ratio of 1.0 (P = 0.14). Under anesthesia with propofol laryngeal injuries were not increased; the risk for residual curarization, however, was lower compared with sevoflurane.
AB - Anesthesia can be maintained with propofol or sevoflurane. Volatile anesthetics increase neuromuscular block of muscle relaxants. We tested the hypothesis, that sevoflurane would cause less vocal cord injuries than an intravenous anesthesia with propofol. In this prospective trial, 65 patients were randomized in 2 groups: SEVO group, anesthesia with sevoflurane, and TIVA group, total intravenous anesthesia with propofol. Intubating and extubating conditions were evaluated. Vocal cord injuries were examined by stroboscopy before and 24 and 72 h after surgery; hoarseness and sore throat were assessed up to 72 h after surgery. Hoarseness and sore throat were comparable between both groups (not significant). Similar findings were observed for vocal cord injuries: 9 (SEVO) versus 5 (TIVA) patients; P = 0.36; the overall incidence was 24%. Type of vocal cord injuries: 9 erythema and 5 edema of the vocal folds. Neuromuscular block was significantly longer in the SEVO group compared with the TIVA group: 71 (range: 38-148) min versus 52 (range: 21-74) min; P < 0.001. Five patients (TIVA group) versus 11 patients (SEVO group) needed neostigmine to achieve a TOF ratio of 1.0 (P = 0.14). Under anesthesia with propofol laryngeal injuries were not increased; the risk for residual curarization, however, was lower compared with sevoflurane.
KW - Journal Article
U2 - 10.1155/2013/723168
DO - 10.1155/2013/723168
M3 - SCORING: Journal article
C2 - 23533393
VL - 2013
SP - 723168
JO - ANESTHESIOL RES PRAC
JF - ANESTHESIOL RES PRAC
SN - 1687-6962
ER -