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Analysis of Risk Factors for Allograft Outcome Comparing 2 Kidneys From the Same Donor in Separate Recipients

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Analysis of Risk Factors for Allograft Outcome Comparing 2 Kidneys From the Same Donor in Separate Recipients. / Radtke, J; Scheidat, S; Achilles, E G; Li, J; Fischer, L; Herden, U; Thaiss, F; Wenzel, U; Nashan, B; Koch, M.

In: TRANSPL P, Vol. 50, No. 10, 12.2018, p. 3211-3215.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Radtke, J, Scheidat, S, Achilles, EG, Li, J, Fischer, L, Herden, U, Thaiss, F, Wenzel, U, Nashan, B & Koch, M 2018, 'Analysis of Risk Factors for Allograft Outcome Comparing 2 Kidneys From the Same Donor in Separate Recipients', TRANSPL P, vol. 50, no. 10, pp. 3211-3215. https://doi.org/10.1016/j.transproceed.2018.08.059

APA

Radtke, J., Scheidat, S., Achilles, E. G., Li, J., Fischer, L., Herden, U., Thaiss, F., Wenzel, U., Nashan, B., & Koch, M. (2018). Analysis of Risk Factors for Allograft Outcome Comparing 2 Kidneys From the Same Donor in Separate Recipients. TRANSPL P, 50(10), 3211-3215. https://doi.org/10.1016/j.transproceed.2018.08.059

Vancouver

Radtke J, Scheidat S, Achilles EG, Li J, Fischer L, Herden U et al. Analysis of Risk Factors for Allograft Outcome Comparing 2 Kidneys From the Same Donor in Separate Recipients. TRANSPL P. 2018 Dec;50(10):3211-3215. https://doi.org/10.1016/j.transproceed.2018.08.059

Bibtex

@article{4a483c629d0d41b9afa59c71e2369b96,
title = "Analysis of Risk Factors for Allograft Outcome Comparing 2 Kidneys From the Same Donor in Separate Recipients",
abstract = "BACKGROUND: An analysis of 2 kidney transplants from the same donor at the same center enables us to analyze the influence of risk factors on the outcome of the grafts in different recipients.METHODS: We retrospectively analyzed 88 kidneys from 44 donors that were implanted in 88 recipients at our institution between 2007-2016. We defined unsatisfactory outcome as glomerular filtration rate <30 mL/min/1.73 m2 allograft loss or recipient death within the first year after transplantation. Fifty-three kidneys were allocated and age-matched to donors above the age of 65 years (via Eurotransplant Senior Program or center offer). We compared kidney pairs with satisfactory outcome in both recipients (group A) to pairs with divergent outcome (group B) and unsatisfactory outcome in both recipients (group C).RESULTS: Thirty-four grafts (17 donors) had a satisfactory outcome for both recipients (group A), and 16 grafts (8 donors) had an unsatisfactory outcome for both recipients (group C). Donor age was significantly higher in group C vs group A (67.5 ± 6.7 vs 56.4 ± 16.0 years, P = .010). The 19 donors donating 1 kidney with satisfactory and the other with unsatisfactory outcome were 67.4 ± 10.7 years old (group B). A severe surgical complication occurred more often in recipients with an unsatisfactory outcome in comparison to patients with a satisfactory outcome.CONCLUSION: Donor age is an important risk factor for an unsatisfactory outcome, either in one or both kidneys of the same donor.",
keywords = "Journal Article",
author = "J Radtke and S Scheidat and Achilles, {E G} and J Li and L Fischer and U Herden and F Thaiss and U Wenzel and B Nashan and M Koch",
note = "Copyright {\textcopyright} 2018 Elsevier Inc. All rights reserved.",
year = "2018",
month = dec,
doi = "10.1016/j.transproceed.2018.08.059",
language = "English",
volume = "50",
pages = "3211--3215",
journal = "TRANSPL P",
issn = "0041-1345",
publisher = "Elsevier USA",
number = "10",

}

RIS

TY - JOUR

T1 - Analysis of Risk Factors for Allograft Outcome Comparing 2 Kidneys From the Same Donor in Separate Recipients

AU - Radtke, J

AU - Scheidat, S

AU - Achilles, E G

AU - Li, J

AU - Fischer, L

AU - Herden, U

AU - Thaiss, F

AU - Wenzel, U

AU - Nashan, B

AU - Koch, M

N1 - Copyright © 2018 Elsevier Inc. All rights reserved.

PY - 2018/12

Y1 - 2018/12

N2 - BACKGROUND: An analysis of 2 kidney transplants from the same donor at the same center enables us to analyze the influence of risk factors on the outcome of the grafts in different recipients.METHODS: We retrospectively analyzed 88 kidneys from 44 donors that were implanted in 88 recipients at our institution between 2007-2016. We defined unsatisfactory outcome as glomerular filtration rate <30 mL/min/1.73 m2 allograft loss or recipient death within the first year after transplantation. Fifty-three kidneys were allocated and age-matched to donors above the age of 65 years (via Eurotransplant Senior Program or center offer). We compared kidney pairs with satisfactory outcome in both recipients (group A) to pairs with divergent outcome (group B) and unsatisfactory outcome in both recipients (group C).RESULTS: Thirty-four grafts (17 donors) had a satisfactory outcome for both recipients (group A), and 16 grafts (8 donors) had an unsatisfactory outcome for both recipients (group C). Donor age was significantly higher in group C vs group A (67.5 ± 6.7 vs 56.4 ± 16.0 years, P = .010). The 19 donors donating 1 kidney with satisfactory and the other with unsatisfactory outcome were 67.4 ± 10.7 years old (group B). A severe surgical complication occurred more often in recipients with an unsatisfactory outcome in comparison to patients with a satisfactory outcome.CONCLUSION: Donor age is an important risk factor for an unsatisfactory outcome, either in one or both kidneys of the same donor.

AB - BACKGROUND: An analysis of 2 kidney transplants from the same donor at the same center enables us to analyze the influence of risk factors on the outcome of the grafts in different recipients.METHODS: We retrospectively analyzed 88 kidneys from 44 donors that were implanted in 88 recipients at our institution between 2007-2016. We defined unsatisfactory outcome as glomerular filtration rate <30 mL/min/1.73 m2 allograft loss or recipient death within the first year after transplantation. Fifty-three kidneys were allocated and age-matched to donors above the age of 65 years (via Eurotransplant Senior Program or center offer). We compared kidney pairs with satisfactory outcome in both recipients (group A) to pairs with divergent outcome (group B) and unsatisfactory outcome in both recipients (group C).RESULTS: Thirty-four grafts (17 donors) had a satisfactory outcome for both recipients (group A), and 16 grafts (8 donors) had an unsatisfactory outcome for both recipients (group C). Donor age was significantly higher in group C vs group A (67.5 ± 6.7 vs 56.4 ± 16.0 years, P = .010). The 19 donors donating 1 kidney with satisfactory and the other with unsatisfactory outcome were 67.4 ± 10.7 years old (group B). A severe surgical complication occurred more often in recipients with an unsatisfactory outcome in comparison to patients with a satisfactory outcome.CONCLUSION: Donor age is an important risk factor for an unsatisfactory outcome, either in one or both kidneys of the same donor.

KW - Journal Article

U2 - 10.1016/j.transproceed.2018.08.059

DO - 10.1016/j.transproceed.2018.08.059

M3 - SCORING: Journal article

C2 - 30577187

VL - 50

SP - 3211

EP - 3215

JO - TRANSPL P

JF - TRANSPL P

SN - 0041-1345

IS - 10

ER -