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An optimized protocol for a standardized, femoral osteotomy model to study fracture healing in mice

Standard

An optimized protocol for a standardized, femoral osteotomy model to study fracture healing in mice. / Jiang, Shan; Knapstein, Paul; Donat, Antonia; Tsitsilonis, Serafeim; Keller, Johannes.

In: STAR PROTOC, Vol. 2, No. 3, 17.09.2021, p. 100798.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Jiang, S, Knapstein, P, Donat, A, Tsitsilonis, S & Keller, J 2021, 'An optimized protocol for a standardized, femoral osteotomy model to study fracture healing in mice', STAR PROTOC, vol. 2, no. 3, pp. 100798. https://doi.org/10.1016/j.xpro.2021.100798

APA

Jiang, S., Knapstein, P., Donat, A., Tsitsilonis, S., & Keller, J. (2021). An optimized protocol for a standardized, femoral osteotomy model to study fracture healing in mice. STAR PROTOC, 2(3), 100798. https://doi.org/10.1016/j.xpro.2021.100798

Vancouver

Jiang S, Knapstein P, Donat A, Tsitsilonis S, Keller J. An optimized protocol for a standardized, femoral osteotomy model to study fracture healing in mice. STAR PROTOC. 2021 Sep 17;2(3):100798. https://doi.org/10.1016/j.xpro.2021.100798

Bibtex

@article{1191f7cc7f3a4c80a7bbadd9f40959da,
title = "An optimized protocol for a standardized, femoral osteotomy model to study fracture healing in mice",
abstract = "Fracture healing represents a dynamic and complex process which depends on the balanced activities of a broad array of different cell types and signaling pathways. Here, we describe a femoral osteotomy protocol for mice, using an external fixator to stabilize the fractured bone. Depending on experimental requirements, the size of the osteotomy gap can be adjusted. Taken together, this protocol describes a highly standardized and reproducible murine model for morphologic and biomolecular assessment of the fracture healing process. For complete details on the use and execution of this protocol, please refer to Appelt et al. (2020).",
author = "Shan Jiang and Paul Knapstein and Antonia Donat and Serafeim Tsitsilonis and Johannes Keller",
note = "{\textcopyright} 2021 The Author(s).",
year = "2021",
month = sep,
day = "17",
doi = "10.1016/j.xpro.2021.100798",
language = "English",
volume = "2",
pages = "100798",
journal = "STAR PROTOC",
issn = "2666-1667",
publisher = "Cell Press",
number = "3",

}

RIS

TY - JOUR

T1 - An optimized protocol for a standardized, femoral osteotomy model to study fracture healing in mice

AU - Jiang, Shan

AU - Knapstein, Paul

AU - Donat, Antonia

AU - Tsitsilonis, Serafeim

AU - Keller, Johannes

N1 - © 2021 The Author(s).

PY - 2021/9/17

Y1 - 2021/9/17

N2 - Fracture healing represents a dynamic and complex process which depends on the balanced activities of a broad array of different cell types and signaling pathways. Here, we describe a femoral osteotomy protocol for mice, using an external fixator to stabilize the fractured bone. Depending on experimental requirements, the size of the osteotomy gap can be adjusted. Taken together, this protocol describes a highly standardized and reproducible murine model for morphologic and biomolecular assessment of the fracture healing process. For complete details on the use and execution of this protocol, please refer to Appelt et al. (2020).

AB - Fracture healing represents a dynamic and complex process which depends on the balanced activities of a broad array of different cell types and signaling pathways. Here, we describe a femoral osteotomy protocol for mice, using an external fixator to stabilize the fractured bone. Depending on experimental requirements, the size of the osteotomy gap can be adjusted. Taken together, this protocol describes a highly standardized and reproducible murine model for morphologic and biomolecular assessment of the fracture healing process. For complete details on the use and execution of this protocol, please refer to Appelt et al. (2020).

U2 - 10.1016/j.xpro.2021.100798

DO - 10.1016/j.xpro.2021.100798

M3 - SCORING: Journal article

C2 - 34527955

VL - 2

SP - 100798

JO - STAR PROTOC

JF - STAR PROTOC

SN - 2666-1667

IS - 3

ER -